Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?

Detalhes bibliográficos
Autor(a) principal: Oliveira, Pedro A. L.
Data de Publicação: 2006
Outros Autores: Garzon, Eliana [UNIFESP], Caboclo, Luís Otávio Sales Ferreira [UNIFESP], Sousa, Patricia da Silva [UNIFESP], Carrete Junior, Henrique [UNIFESP], Centeno, Ricardo Silva [UNIFESP], Costa, José Maria P., Machado, Helio Rubens, Yacubian, Elza Márcia Targas [UNIFESP], Bianchin, Marino Muxfeldt, Sakamoto, Américo Ceiki [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1016/j.seizure.2006.06.009
http://repositorio.unifesp.br/handle/11600/29162
Resumo: Introduction: Intraoperative electrocorticography (ECoG) can be performed in cases of temporal lobe epilepsy due to hippocampal sclerosis (TLE-HS). However, its significance and correlation with surgical outcome are still controversial.Objectives: To analyze the electrophysiological characteristics of temporal lobe structures during ECoG of patients with TLE-HS, with emphasis on the comparison between pre- and post-resection recordings and surgical outcome.Patients and methods: Seventeen patients with refractory TLE-HS submitted to corticoamigdalohipocampectomy were included in the study. Clinical variables included age at the onset, duration of epilepsy and seizure outcome. the postoperative follow-up ranged from 24 to 36 months. According to outcome subjects were divided in two subgroups: (A) individuals free of seizures (Engel 1A), and (B) individuals not-free of seizures (Engel 1B-IV). Four patterns of ECoG findings were identified: isolated discharges; high frequency spikes (HFS); continuous discharges; combination of isolated discharges and HFS. According to predominant topography ECoG was classified as mediobasal, lateral (or neocortical), mediobasal and lateral.Results: the progressive removal of the temporal pole and the hippocampus was associated with significant decrease of neocortical spikes. No correlation between clinical variables and seizure outcome was observed. Patients who only had isolated spikes on intraoperative ECoG presented a statistical trend for excellent surgical control. Patients who presented temporal pole blurring on MRI also had better post-surgical seizure outcome.Conclusions: This study showed that out of diverse clinical and laboratory variables, only isolated discharges on intraoperative ECoG and temporal pole blurring on MRI predicted excellent post-surgicat seizure outcome. However, other studies with larger number of patients are stilt necessary to confirm these findings. (C) 2006 British Epilepsy Association. Published by Elsevier B.V. All rights reserved.
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spelling Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?electrocorticographytemporal lobe epilepsyhippocampus sclerosisIntroduction: Intraoperative electrocorticography (ECoG) can be performed in cases of temporal lobe epilepsy due to hippocampal sclerosis (TLE-HS). However, its significance and correlation with surgical outcome are still controversial.Objectives: To analyze the electrophysiological characteristics of temporal lobe structures during ECoG of patients with TLE-HS, with emphasis on the comparison between pre- and post-resection recordings and surgical outcome.Patients and methods: Seventeen patients with refractory TLE-HS submitted to corticoamigdalohipocampectomy were included in the study. Clinical variables included age at the onset, duration of epilepsy and seizure outcome. the postoperative follow-up ranged from 24 to 36 months. According to outcome subjects were divided in two subgroups: (A) individuals free of seizures (Engel 1A), and (B) individuals not-free of seizures (Engel 1B-IV). Four patterns of ECoG findings were identified: isolated discharges; high frequency spikes (HFS); continuous discharges; combination of isolated discharges and HFS. According to predominant topography ECoG was classified as mediobasal, lateral (or neocortical), mediobasal and lateral.Results: the progressive removal of the temporal pole and the hippocampus was associated with significant decrease of neocortical spikes. No correlation between clinical variables and seizure outcome was observed. Patients who only had isolated spikes on intraoperative ECoG presented a statistical trend for excellent surgical control. Patients who presented temporal pole blurring on MRI also had better post-surgical seizure outcome.Conclusions: This study showed that out of diverse clinical and laboratory variables, only isolated discharges on intraoperative ECoG and temporal pole blurring on MRI predicted excellent post-surgicat seizure outcome. However, other studies with larger number of patients are stilt necessary to confirm these findings. (C) 2006 British Epilepsy Association. Published by Elsevier B.V. All rights reserved.Universidade Federal de São Paulo, Dept Neurol & Neurosurg, Div Neurol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Radiol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Neurol & Neurosurg, Div Neurosurg, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Anesthesiol, São Paulo, BrazilUniv São Paulo, Ribeirao Preto Med Sch, Dept Surg, Div Neurosurg, São Paulo, BrazilUniv São Paulo, Ribeirao Preto Med Sch, Dept Neurol Psychiat & Clin Psychol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Neurol & Neurosurg, Div Neurol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Radiol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Neurol & Neurosurg, Div Neurosurg, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Anesthesiol, São Paulo, BrazilWeb of ScienceW B Saunders Co LtdUniversidade Federal de São Paulo (UNIFESP)Universidade de São Paulo (USP)Oliveira, Pedro A. L.Garzon, Eliana [UNIFESP]Caboclo, Luís Otávio Sales Ferreira [UNIFESP]Sousa, Patricia da Silva [UNIFESP]Carrete Junior, Henrique [UNIFESP]Centeno, Ricardo Silva [UNIFESP]Costa, José Maria P.Machado, Helio RubensYacubian, Elza Márcia Targas [UNIFESP]Bianchin, Marino MuxfeldtSakamoto, Américo Ceiki [UNIFESP]2016-01-24T12:41:29Z2016-01-24T12:41:29Z2006-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion541-551application/pdfhttp://dx.doi.org/10.1016/j.seizure.2006.06.009Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 15, n. 7, p. 541-551, 2006.10.1016/j.seizure.2006.06.009WOS000240864700010.pdf1059-1311http://repositorio.unifesp.br/handle/11600/29162WOS:000240864700010engSeizure-european Journal of Epilepsyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-31T03:58:31Zoai:repositorio.unifesp.br/:11600/29162Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-31T03:58:31Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?
title Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?
spellingShingle Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?
Oliveira, Pedro A. L.
electrocorticography
temporal lobe epilepsy
hippocampus sclerosis
title_short Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?
title_full Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?
title_fullStr Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?
title_full_unstemmed Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?
title_sort Can intraoperative electrocorticography patterns predict surgical outcome in patients with temporal lobe epilepsy secondary to unilateral mesial temporal sclerosis?
author Oliveira, Pedro A. L.
author_facet Oliveira, Pedro A. L.
Garzon, Eliana [UNIFESP]
Caboclo, Luís Otávio Sales Ferreira [UNIFESP]
Sousa, Patricia da Silva [UNIFESP]
Carrete Junior, Henrique [UNIFESP]
Centeno, Ricardo Silva [UNIFESP]
Costa, José Maria P.
Machado, Helio Rubens
Yacubian, Elza Márcia Targas [UNIFESP]
Bianchin, Marino Muxfeldt
Sakamoto, Américo Ceiki [UNIFESP]
author_role author
author2 Garzon, Eliana [UNIFESP]
Caboclo, Luís Otávio Sales Ferreira [UNIFESP]
Sousa, Patricia da Silva [UNIFESP]
Carrete Junior, Henrique [UNIFESP]
Centeno, Ricardo Silva [UNIFESP]
Costa, José Maria P.
Machado, Helio Rubens
Yacubian, Elza Márcia Targas [UNIFESP]
Bianchin, Marino Muxfeldt
Sakamoto, Américo Ceiki [UNIFESP]
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
dc.contributor.author.fl_str_mv Oliveira, Pedro A. L.
Garzon, Eliana [UNIFESP]
Caboclo, Luís Otávio Sales Ferreira [UNIFESP]
Sousa, Patricia da Silva [UNIFESP]
Carrete Junior, Henrique [UNIFESP]
Centeno, Ricardo Silva [UNIFESP]
Costa, José Maria P.
Machado, Helio Rubens
Yacubian, Elza Márcia Targas [UNIFESP]
Bianchin, Marino Muxfeldt
Sakamoto, Américo Ceiki [UNIFESP]
dc.subject.por.fl_str_mv electrocorticography
temporal lobe epilepsy
hippocampus sclerosis
topic electrocorticography
temporal lobe epilepsy
hippocampus sclerosis
description Introduction: Intraoperative electrocorticography (ECoG) can be performed in cases of temporal lobe epilepsy due to hippocampal sclerosis (TLE-HS). However, its significance and correlation with surgical outcome are still controversial.Objectives: To analyze the electrophysiological characteristics of temporal lobe structures during ECoG of patients with TLE-HS, with emphasis on the comparison between pre- and post-resection recordings and surgical outcome.Patients and methods: Seventeen patients with refractory TLE-HS submitted to corticoamigdalohipocampectomy were included in the study. Clinical variables included age at the onset, duration of epilepsy and seizure outcome. the postoperative follow-up ranged from 24 to 36 months. According to outcome subjects were divided in two subgroups: (A) individuals free of seizures (Engel 1A), and (B) individuals not-free of seizures (Engel 1B-IV). Four patterns of ECoG findings were identified: isolated discharges; high frequency spikes (HFS); continuous discharges; combination of isolated discharges and HFS. According to predominant topography ECoG was classified as mediobasal, lateral (or neocortical), mediobasal and lateral.Results: the progressive removal of the temporal pole and the hippocampus was associated with significant decrease of neocortical spikes. No correlation between clinical variables and seizure outcome was observed. Patients who only had isolated spikes on intraoperative ECoG presented a statistical trend for excellent surgical control. Patients who presented temporal pole blurring on MRI also had better post-surgical seizure outcome.Conclusions: This study showed that out of diverse clinical and laboratory variables, only isolated discharges on intraoperative ECoG and temporal pole blurring on MRI predicted excellent post-surgicat seizure outcome. However, other studies with larger number of patients are stilt necessary to confirm these findings. (C) 2006 British Epilepsy Association. Published by Elsevier B.V. All rights reserved.
publishDate 2006
dc.date.none.fl_str_mv 2006-10-01
2016-01-24T12:41:29Z
2016-01-24T12:41:29Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.seizure.2006.06.009
Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 15, n. 7, p. 541-551, 2006.
10.1016/j.seizure.2006.06.009
WOS000240864700010.pdf
1059-1311
http://repositorio.unifesp.br/handle/11600/29162
WOS:000240864700010
url http://dx.doi.org/10.1016/j.seizure.2006.06.009
http://repositorio.unifesp.br/handle/11600/29162
identifier_str_mv Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 15, n. 7, p. 541-551, 2006.
10.1016/j.seizure.2006.06.009
WOS000240864700010.pdf
1059-1311
WOS:000240864700010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Seizure-european Journal of Epilepsy
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 541-551
application/pdf
dc.publisher.none.fl_str_mv W B Saunders Co Ltd
publisher.none.fl_str_mv W B Saunders Co Ltd
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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