Reference values for lung function tests: I. Static volumes

Detalhes bibliográficos
Autor(a) principal: Neder, Jose Alberto [UNIFESP]
Data de Publicação: 1999
Outros Autores: Andreoni, Solange [UNIFESP], Castelo Filho, Adauto [UNIFESP], Nery, Luiz Eduardo [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0100-879X1999000600006
http://repositorio.unifesp.br/handle/11600/792
Resumo: Static lung volume (LV) measurements have a number of clinical and research applications; however, no previous studies have provided reference values for such tests using a healthy sample of the adult Brazilian population. With this as our main purpose, we prospectively evaluated 100 non-smoking subjects (50 males and 50 females), 20 to 80 years old, randomly selected from more than 8,000 individuals. Gender-specific linear prediction equations were developed by multiple regression analysis with total lung capacity (TLC), functional residual capacity (FRC), residual volume (RV), RV/TLC ratio and inspiratory capacity (IC) as dependent variables, and with age, height, weight, lean body mass and indexes of physical fitness as independent ones. Simpler demographic and anthropometric variables were as useful as more complex measurements in predicting LV values, independent of gender and age (R2 values ranging from 0.49 to 0.78, P<0.001). Interestingly, prediction equations from North American and European studies overestimated the LV at low volumes and underestimated them at high volumes (P<0.05). Our results, therefore, provide a more appropriate frame of reference to evaluate the normalcy of static lung volume values in Brazilian males and females aged 20 to 80 years.
id UFSP_12d2be414f74c683804d40d5a7261d19
oai_identifier_str oai:repositorio.unifesp.br/:11600/792
network_acronym_str UFSP
network_name_str Repositório Institucional da UNIFESP
repository_id_str 3465
spelling Reference values for lung function tests: I. Static volumeslung volumespulmonary function testspulmonary diseasesStatic lung volume (LV) measurements have a number of clinical and research applications; however, no previous studies have provided reference values for such tests using a healthy sample of the adult Brazilian population. With this as our main purpose, we prospectively evaluated 100 non-smoking subjects (50 males and 50 females), 20 to 80 years old, randomly selected from more than 8,000 individuals. Gender-specific linear prediction equations were developed by multiple regression analysis with total lung capacity (TLC), functional residual capacity (FRC), residual volume (RV), RV/TLC ratio and inspiratory capacity (IC) as dependent variables, and with age, height, weight, lean body mass and indexes of physical fitness as independent ones. Simpler demographic and anthropometric variables were as useful as more complex measurements in predicting LV values, independent of gender and age (R2 values ranging from 0.49 to 0.78, P<0.001). Interestingly, prediction equations from North American and European studies overestimated the LV at low volumes and underestimated them at high volumes (P<0.05). Our results, therefore, provide a more appropriate frame of reference to evaluate the normalcy of static lung volume values in Brazilian males and females aged 20 to 80 years.University of LondonUniversidade Federal de São Paulo (UNIFESP)Univesidade Federal de São PauloUNIFESP, EPM, Sao Paulo, BrazilSciELOAssociação Brasileira de Divulgação CientíficaUniversity of LondonUniversidade Federal de São Paulo (UNIFESP)Univesidade Federal de São PauloNeder, Jose Alberto [UNIFESP]Andreoni, Solange [UNIFESP]Castelo Filho, Adauto [UNIFESP]Nery, Luiz Eduardo [UNIFESP]2015-06-14T13:24:53Z2015-06-14T13:24:53Z1999-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion703-717application/pdfhttp://dx.doi.org/10.1590/S0100-879X1999000600006Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 32, n. 6, p. 703-717, 1999.10.1590/S0100-879X1999000600006S0100-879X1999000600006.pdf0100-879XS0100-879X1999000600006http://repositorio.unifesp.br/handle/11600/792WOS:000080896000006engBrazilian Journal of Medical and Biological Researchinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-10-10T10:58:55Zoai:repositorio.unifesp.br/:11600/792Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-10-10T10:58:55Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Reference values for lung function tests: I. Static volumes
title Reference values for lung function tests: I. Static volumes
spellingShingle Reference values for lung function tests: I. Static volumes
Neder, Jose Alberto [UNIFESP]
lung volumes
pulmonary function tests
pulmonary diseases
title_short Reference values for lung function tests: I. Static volumes
title_full Reference values for lung function tests: I. Static volumes
title_fullStr Reference values for lung function tests: I. Static volumes
title_full_unstemmed Reference values for lung function tests: I. Static volumes
title_sort Reference values for lung function tests: I. Static volumes
author Neder, Jose Alberto [UNIFESP]
author_facet Neder, Jose Alberto [UNIFESP]
Andreoni, Solange [UNIFESP]
Castelo Filho, Adauto [UNIFESP]
Nery, Luiz Eduardo [UNIFESP]
author_role author
author2 Andreoni, Solange [UNIFESP]
Castelo Filho, Adauto [UNIFESP]
Nery, Luiz Eduardo [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv University of London
Universidade Federal de São Paulo (UNIFESP)
Univesidade Federal de São Paulo
dc.contributor.author.fl_str_mv Neder, Jose Alberto [UNIFESP]
Andreoni, Solange [UNIFESP]
Castelo Filho, Adauto [UNIFESP]
Nery, Luiz Eduardo [UNIFESP]
dc.subject.por.fl_str_mv lung volumes
pulmonary function tests
pulmonary diseases
topic lung volumes
pulmonary function tests
pulmonary diseases
description Static lung volume (LV) measurements have a number of clinical and research applications; however, no previous studies have provided reference values for such tests using a healthy sample of the adult Brazilian population. With this as our main purpose, we prospectively evaluated 100 non-smoking subjects (50 males and 50 females), 20 to 80 years old, randomly selected from more than 8,000 individuals. Gender-specific linear prediction equations were developed by multiple regression analysis with total lung capacity (TLC), functional residual capacity (FRC), residual volume (RV), RV/TLC ratio and inspiratory capacity (IC) as dependent variables, and with age, height, weight, lean body mass and indexes of physical fitness as independent ones. Simpler demographic and anthropometric variables were as useful as more complex measurements in predicting LV values, independent of gender and age (R2 values ranging from 0.49 to 0.78, P<0.001). Interestingly, prediction equations from North American and European studies overestimated the LV at low volumes and underestimated them at high volumes (P<0.05). Our results, therefore, provide a more appropriate frame of reference to evaluate the normalcy of static lung volume values in Brazilian males and females aged 20 to 80 years.
publishDate 1999
dc.date.none.fl_str_mv 1999-06-01
2015-06-14T13:24:53Z
2015-06-14T13:24:53Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0100-879X1999000600006
Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 32, n. 6, p. 703-717, 1999.
10.1590/S0100-879X1999000600006
S0100-879X1999000600006.pdf
0100-879X
S0100-879X1999000600006
http://repositorio.unifesp.br/handle/11600/792
WOS:000080896000006
url http://dx.doi.org/10.1590/S0100-879X1999000600006
http://repositorio.unifesp.br/handle/11600/792
identifier_str_mv Brazilian Journal of Medical and Biological Research. Associação Brasileira de Divulgação Científica, v. 32, n. 6, p. 703-717, 1999.
10.1590/S0100-879X1999000600006
S0100-879X1999000600006.pdf
0100-879X
S0100-879X1999000600006
WOS:000080896000006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Brazilian Journal of Medical and Biological Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 703-717
application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268448910344192