Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach

Detalhes bibliográficos
Autor(a) principal: Buffolo, Enio [UNIFESP]
Data de Publicação: 2002
Outros Autores: Fonseca, José Honório Palma da [UNIFESP], Souza, José Augusto Marcondes de [UNIFESP], Alves, Claudia Maria Rodrigues [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
dARK ID: ark:/48912/001300000k0gh
DOI: 10.1016/S0003-4975(02)04138-3
Texto Completo: http://dx.doi.org/10.1016/S0003-4975(02)04138-3
http://repositorio.unifesp.br/handle/11600/27008
Resumo: Background. Acute aortic dissection is a life-threatening medical condition. It is associated with high morbidity and mortality. Type B dissections are usually managed clinically during the acute phase. Conventional surgery carries high mortality rates due to the presence of serious complications. We herein present treatment of this condition with a less invasive endovascular approach. Other clinical situations such as penetrating ulcers, intramural hematomas, and true aneurysms of descending aorta were similarly treated.Methods. From December 1996 to March 2002, 191 patients with type B dissections were treated with self-expandable, polyester-covered stents. There were 120 patients (62.8%) with type B dissections, 61 patients (31.9%) with true aneurysms, 6 patients (3.1%) with penetrating ulcers or intramural hematomas, and 4 patients (2.1%) with trauma. Patients with abdominal aneurysms (44) and stents introduced under direct vision through the aortic arch (70) were excluded. the stent graft was delivered in the catheterization laboratory under general anesthesia, with induced hypotension and heparinization. All stents used were made in Brazil (Braile Biomedics, Sao Jose do Rio Preto, SP).Results. the procedure was performed in 191 consecutive cases. the success rate was 91.1% (174/191). Success was defined as occlusion of the thoracic intimal tear, or exclusion of the aneurysm without leaks. Hospital mortality was 10.4% (20/191 patients), due to preoperative comorbidities. Six patients required conversion to surgery. No case of paraplegia was observed. An actuarial survival curve showed 87.4% +/- 29% survival in the late follow-up period.Conclusions. Stent grafts are an important development in the treatment of descending aortic aneurysms or dissections. This novel approach may replace conventional surgical treatment of these conditions, with earlier intervention and less morbidity.
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spelling Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approachBackground. Acute aortic dissection is a life-threatening medical condition. It is associated with high morbidity and mortality. Type B dissections are usually managed clinically during the acute phase. Conventional surgery carries high mortality rates due to the presence of serious complications. We herein present treatment of this condition with a less invasive endovascular approach. Other clinical situations such as penetrating ulcers, intramural hematomas, and true aneurysms of descending aorta were similarly treated.Methods. From December 1996 to March 2002, 191 patients with type B dissections were treated with self-expandable, polyester-covered stents. There were 120 patients (62.8%) with type B dissections, 61 patients (31.9%) with true aneurysms, 6 patients (3.1%) with penetrating ulcers or intramural hematomas, and 4 patients (2.1%) with trauma. Patients with abdominal aneurysms (44) and stents introduced under direct vision through the aortic arch (70) were excluded. the stent graft was delivered in the catheterization laboratory under general anesthesia, with induced hypotension and heparinization. All stents used were made in Brazil (Braile Biomedics, Sao Jose do Rio Preto, SP).Results. the procedure was performed in 191 consecutive cases. the success rate was 91.1% (174/191). Success was defined as occlusion of the thoracic intimal tear, or exclusion of the aneurysm without leaks. Hospital mortality was 10.4% (20/191 patients), due to preoperative comorbidities. Six patients required conversion to surgery. No case of paraplegia was observed. An actuarial survival curve showed 87.4% +/- 29% survival in the late follow-up period.Conclusions. Stent grafts are an important development in the treatment of descending aortic aneurysms or dissections. This novel approach may replace conventional surgical treatment of these conditions, with earlier intervention and less morbidity.Universidade Federal de São Paulo, Paulista Sch Med, São Paulo, SP, BrazilAffiliated Hosp, São Paulo, SP, BrazilUniversidade Federal de São Paulo, Paulista Sch Med, São Paulo, SP, BrazilWeb of ScienceElsevier B.V.Universidade Federal de São Paulo (UNIFESP)Affiliated HospBuffolo, Enio [UNIFESP]Fonseca, José Honório Palma da [UNIFESP]Souza, José Augusto Marcondes de [UNIFESP]Alves, Claudia Maria Rodrigues [UNIFESP]2016-01-24T12:33:33Z2016-01-24T12:33:33Z2002-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionS1815-S1817http://dx.doi.org/10.1016/S0003-4975(02)04138-3Annals of Thoracic Surgery. New York: Elsevier B.V., v. 74, n. 5, p. S1815-S1817, 2002.10.1016/S0003-4975(02)04138-30003-4975http://repositorio.unifesp.br/handle/11600/27008WOS:000179262300101ark:/48912/001300000k0ghengAnnals of Thoracic Surgeryinfo:eu-repo/semantics/openAccesshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2016-01-24T10:33:33Zoai:repositorio.unifesp.br/:11600/27008Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:22:11.404141Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
title Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
spellingShingle Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
Buffolo, Enio [UNIFESP]
Buffolo, Enio [UNIFESP]
title_short Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
title_full Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
title_fullStr Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
title_full_unstemmed Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
title_sort Revolutionary treatment of aneurysms and dissections of descending aorta: the endovascular approach
author Buffolo, Enio [UNIFESP]
author_facet Buffolo, Enio [UNIFESP]
Buffolo, Enio [UNIFESP]
Fonseca, José Honório Palma da [UNIFESP]
Souza, José Augusto Marcondes de [UNIFESP]
Alves, Claudia Maria Rodrigues [UNIFESP]
Fonseca, José Honório Palma da [UNIFESP]
Souza, José Augusto Marcondes de [UNIFESP]
Alves, Claudia Maria Rodrigues [UNIFESP]
author_role author
author2 Fonseca, José Honório Palma da [UNIFESP]
Souza, José Augusto Marcondes de [UNIFESP]
Alves, Claudia Maria Rodrigues [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Affiliated Hosp
dc.contributor.author.fl_str_mv Buffolo, Enio [UNIFESP]
Fonseca, José Honório Palma da [UNIFESP]
Souza, José Augusto Marcondes de [UNIFESP]
Alves, Claudia Maria Rodrigues [UNIFESP]
description Background. Acute aortic dissection is a life-threatening medical condition. It is associated with high morbidity and mortality. Type B dissections are usually managed clinically during the acute phase. Conventional surgery carries high mortality rates due to the presence of serious complications. We herein present treatment of this condition with a less invasive endovascular approach. Other clinical situations such as penetrating ulcers, intramural hematomas, and true aneurysms of descending aorta were similarly treated.Methods. From December 1996 to March 2002, 191 patients with type B dissections were treated with self-expandable, polyester-covered stents. There were 120 patients (62.8%) with type B dissections, 61 patients (31.9%) with true aneurysms, 6 patients (3.1%) with penetrating ulcers or intramural hematomas, and 4 patients (2.1%) with trauma. Patients with abdominal aneurysms (44) and stents introduced under direct vision through the aortic arch (70) were excluded. the stent graft was delivered in the catheterization laboratory under general anesthesia, with induced hypotension and heparinization. All stents used were made in Brazil (Braile Biomedics, Sao Jose do Rio Preto, SP).Results. the procedure was performed in 191 consecutive cases. the success rate was 91.1% (174/191). Success was defined as occlusion of the thoracic intimal tear, or exclusion of the aneurysm without leaks. Hospital mortality was 10.4% (20/191 patients), due to preoperative comorbidities. Six patients required conversion to surgery. No case of paraplegia was observed. An actuarial survival curve showed 87.4% +/- 29% survival in the late follow-up period.Conclusions. Stent grafts are an important development in the treatment of descending aortic aneurysms or dissections. This novel approach may replace conventional surgical treatment of these conditions, with earlier intervention and less morbidity.
publishDate 2002
dc.date.none.fl_str_mv 2002-11-01
2016-01-24T12:33:33Z
2016-01-24T12:33:33Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/S0003-4975(02)04138-3
Annals of Thoracic Surgery. New York: Elsevier B.V., v. 74, n. 5, p. S1815-S1817, 2002.
10.1016/S0003-4975(02)04138-3
0003-4975
http://repositorio.unifesp.br/handle/11600/27008
WOS:000179262300101
dc.identifier.dark.fl_str_mv ark:/48912/001300000k0gh
url http://dx.doi.org/10.1016/S0003-4975(02)04138-3
http://repositorio.unifesp.br/handle/11600/27008
identifier_str_mv Annals of Thoracic Surgery. New York: Elsevier B.V., v. 74, n. 5, p. S1815-S1817, 2002.
10.1016/S0003-4975(02)04138-3
0003-4975
WOS:000179262300101
ark:/48912/001300000k0gh
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Annals of Thoracic Surgery
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
eu_rights_str_mv openAccess
rights_invalid_str_mv http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.format.none.fl_str_mv S1815-S1817
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
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reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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dc.identifier.doi.none.fl_str_mv 10.1016/S0003-4975(02)04138-3