Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa

Detalhes bibliográficos
Autor(a) principal: Haraguchi, Daniel Keizo de Medeiros
Data de Publicação: 2003
Outros Autores: Gomes, José Álvaro Pereira [UNIFESP], Sato, Elcio Hideo [UNIFESP], Novo, Neil Ferreira [UNIFESP], Freitas, Denise de [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0004-27492003000200002
http://repositorio.unifesp.br/handle/11600/1613
Resumo: PURPOSE: To evaluate the therapeutic effect on amniotic membrane transplantation in symptomatic bullous keratopathy. METHODS: Nine patients with symptomatic bullous keratopathy, candidates or not for penetrating keratoplasty were evaluated before, 1, 3, 6 and 12 months after amniotic membrane transplantation. During each visit, patients have been asked about pain, photophobia, and foreign body sensation and were submitted to complete ophthalmological evaluation, esthesiometry and ultrasound pachymetry. RESULTS: Comparing evaluations performed previously and after the procedure regarding pain, photophobia, foreign body sensation and esthesiometry, there was a statistical significant reduction in symptoms and corneal sensitivity. Medium pachymetry showed an increased thickness soon after the procedure and decreasing between 6 and 12 months. It was observed that after 6 months of follow-up, the transplanted amniotic membrane became partially dissolved in 3 cases (33.3%) and totally dissolved in other 3 cases (33.3%). CONCLUSION: Amniotic membrane transplantation represents an effective alternative for the treatment of symptomatic bullous keratopathy up to 12 months of follow-up.
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spelling Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosaUse of amniotic membrane transplantation to treat bullous keratopathyAmnionTransplantation, heterotopicCorneal diseasesÂmnioTransplante heterotópicoDoenças da córneaPURPOSE: To evaluate the therapeutic effect on amniotic membrane transplantation in symptomatic bullous keratopathy. METHODS: Nine patients with symptomatic bullous keratopathy, candidates or not for penetrating keratoplasty were evaluated before, 1, 3, 6 and 12 months after amniotic membrane transplantation. During each visit, patients have been asked about pain, photophobia, and foreign body sensation and were submitted to complete ophthalmological evaluation, esthesiometry and ultrasound pachymetry. RESULTS: Comparing evaluations performed previously and after the procedure regarding pain, photophobia, foreign body sensation and esthesiometry, there was a statistical significant reduction in symptoms and corneal sensitivity. Medium pachymetry showed an increased thickness soon after the procedure and decreasing between 6 and 12 months. It was observed that after 6 months of follow-up, the transplanted amniotic membrane became partially dissolved in 3 cases (33.3%) and totally dissolved in other 3 cases (33.3%). CONCLUSION: Amniotic membrane transplantation represents an effective alternative for the treatment of symptomatic bullous keratopathy up to 12 months of follow-up.OBJETIVO: Avaliar o efeito terapêutico do transplante de membrana amniótica no tratamento da ceratopatia bolhosa. MÉTODOS: Nove pacientes portadores de ceratopatia bolhosa sintomática, com baixa acuidade visual, com e sem indicação de transplante de córnea foram avaliados antes, 1, 3, 6 e 12 meses após transplante de membrana amniótica. Em cada visita, os pacientes foram questionados sobre intensidade da dor, fotofobia, sensação de corpo estranho, e submetidos a exame oftalmológico completo,estesiometria e paquimetria. RESULTADOS: As comparações realizadas entre os valores antes e após o procedimento referentes à dor, fotofobia, sensação de corpo estranho e estesiometria apresentaram diferenças estatisticamente significantes quanto à diminuição desses sintomas e da sensibilidade corneal (p<0,05). A paquimetria apresentou aumento da espessura logo após o procedimento e uma diminuição entre as avaliações de 6 e 12 meses, que foram estatisticamente significantes (p<0,05). Após o sexto mês de seguimento, observou-se reabsorção parcial da membrana amniótica em 3 casos (33,3%) e reabsorção total em outros 3 casos (33,3%). CONCLUSÃO: O transplante de membrana amniótica representa modalidade efetiva no controle dos sintomas da ceratopatia bolhosa por até 12 meses.Universidade Federal de São Paulo (UNIFESP) Departamento de Oftalmologia Setor de Córnea e Doenças ExternasUNISA Faculdade de Medicina de Santo AmaroUNIFESP, Depto. de Oftalmologia Setor de Córnea e Doenças ExternasSciELOConselho Brasileiro de OftalmologiaUniversidade Federal de São Paulo (UNIFESP)UNISA Faculdade de Medicina de Santo AmaroHaraguchi, Daniel Keizo de MedeirosGomes, José Álvaro Pereira [UNIFESP]Sato, Elcio Hideo [UNIFESP]Novo, Neil Ferreira [UNIFESP]Freitas, Denise de [UNIFESP]2015-06-14T13:29:53Z2015-06-14T13:29:53Z2003-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion121-124application/pdfhttp://dx.doi.org/10.1590/S0004-27492003000200002Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 66, n. 2, p. 121-124, 2003.10.1590/S0004-27492003000200002S0004-27492003000200002.pdf0004-2749S0004-27492003000200002http://repositorio.unifesp.br/handle/11600/1613porArquivos Brasileiros de Oftalmologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T16:00:31Zoai:repositorio.unifesp.br/:11600/1613Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-05T16:00:31Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa
Use of amniotic membrane transplantation to treat bullous keratopathy
title Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa
spellingShingle Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa
Haraguchi, Daniel Keizo de Medeiros
Amnion
Transplantation, heterotopic
Corneal diseases
Âmnio
Transplante heterotópico
Doenças da córnea
title_short Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa
title_full Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa
title_fullStr Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa
title_full_unstemmed Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa
title_sort Uso de transplante de membrana amniótica no tratamento da ceratopatia bolhosa
author Haraguchi, Daniel Keizo de Medeiros
author_facet Haraguchi, Daniel Keizo de Medeiros
Gomes, José Álvaro Pereira [UNIFESP]
Sato, Elcio Hideo [UNIFESP]
Novo, Neil Ferreira [UNIFESP]
Freitas, Denise de [UNIFESP]
author_role author
author2 Gomes, José Álvaro Pereira [UNIFESP]
Sato, Elcio Hideo [UNIFESP]
Novo, Neil Ferreira [UNIFESP]
Freitas, Denise de [UNIFESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
UNISA Faculdade de Medicina de Santo Amaro
dc.contributor.author.fl_str_mv Haraguchi, Daniel Keizo de Medeiros
Gomes, José Álvaro Pereira [UNIFESP]
Sato, Elcio Hideo [UNIFESP]
Novo, Neil Ferreira [UNIFESP]
Freitas, Denise de [UNIFESP]
dc.subject.por.fl_str_mv Amnion
Transplantation, heterotopic
Corneal diseases
Âmnio
Transplante heterotópico
Doenças da córnea
topic Amnion
Transplantation, heterotopic
Corneal diseases
Âmnio
Transplante heterotópico
Doenças da córnea
description PURPOSE: To evaluate the therapeutic effect on amniotic membrane transplantation in symptomatic bullous keratopathy. METHODS: Nine patients with symptomatic bullous keratopathy, candidates or not for penetrating keratoplasty were evaluated before, 1, 3, 6 and 12 months after amniotic membrane transplantation. During each visit, patients have been asked about pain, photophobia, and foreign body sensation and were submitted to complete ophthalmological evaluation, esthesiometry and ultrasound pachymetry. RESULTS: Comparing evaluations performed previously and after the procedure regarding pain, photophobia, foreign body sensation and esthesiometry, there was a statistical significant reduction in symptoms and corneal sensitivity. Medium pachymetry showed an increased thickness soon after the procedure and decreasing between 6 and 12 months. It was observed that after 6 months of follow-up, the transplanted amniotic membrane became partially dissolved in 3 cases (33.3%) and totally dissolved in other 3 cases (33.3%). CONCLUSION: Amniotic membrane transplantation represents an effective alternative for the treatment of symptomatic bullous keratopathy up to 12 months of follow-up.
publishDate 2003
dc.date.none.fl_str_mv 2003-01-01
2015-06-14T13:29:53Z
2015-06-14T13:29:53Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0004-27492003000200002
Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 66, n. 2, p. 121-124, 2003.
10.1590/S0004-27492003000200002
S0004-27492003000200002.pdf
0004-2749
S0004-27492003000200002
http://repositorio.unifesp.br/handle/11600/1613
url http://dx.doi.org/10.1590/S0004-27492003000200002
http://repositorio.unifesp.br/handle/11600/1613
identifier_str_mv Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 66, n. 2, p. 121-124, 2003.
10.1590/S0004-27492003000200002
S0004-27492003000200002.pdf
0004-2749
S0004-27492003000200002
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Arquivos Brasileiros de Oftalmologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 121-124
application/pdf
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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