Anaplastic meningioma: case report

Detalhes bibliográficos
Autor(a) principal: Falavigna, Asdrubal [UNIFESP]
Data de Publicação: 2001
Outros Autores: Santos, José Augusto Nasser dos [UNIFESP], Chimelli, Leila, Ferraz, Fernando Antonio Patriani [UNIFESP], Bonatelli, Antonio de Padua Furquim [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0004-282X2001000600019
http://repositorio.unifesp.br/handle/11600/1284
Resumo: Intracranial meningiomas continue to challenge our best clinical efforts to eliminate them once discovered and deemed appropriate for treatment. Malignant meningiomas constitute 10% to 15% of all meningiomas and limited information exists regarding adjuvant treatment. The external whole brain irradiation is recommended. Traditional chemotherapy has proven ineffective; thus, new chemotherapeutic agents and new methods of delivery should be developed. Immunotherapy may be considered for patients with malignant meningiomas when all others previous treatment have failed. We report a case of anaplastic papillary meningioma. A 67-year-old man presented with partial complex seizures, headache and aggressiveness. A computerized tomography and magnetic resonance image demonstrated a large left temporo-occipital mass with difuse contrast enhancement and extensive surrounding edema. A left temporo-occipital flap was performed. The tumor and the infiltrated dura were radically removed. Postoperatively, the patient remained neurologically intact. The treatment was complemented by external whole brain radiation.
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spelling Anaplastic meningioma: case reportMeningioma anaplásico: relato de casopapillary meningiomapathologyradiotherapychemotherapymeningeoma papilarpatologiaradioterapiaquimioterapiaIntracranial meningiomas continue to challenge our best clinical efforts to eliminate them once discovered and deemed appropriate for treatment. Malignant meningiomas constitute 10% to 15% of all meningiomas and limited information exists regarding adjuvant treatment. The external whole brain irradiation is recommended. Traditional chemotherapy has proven ineffective; thus, new chemotherapeutic agents and new methods of delivery should be developed. Immunotherapy may be considered for patients with malignant meningiomas when all others previous treatment have failed. We report a case of anaplastic papillary meningioma. A 67-year-old man presented with partial complex seizures, headache and aggressiveness. A computerized tomography and magnetic resonance image demonstrated a large left temporo-occipital mass with difuse contrast enhancement and extensive surrounding edema. A left temporo-occipital flap was performed. The tumor and the infiltrated dura were radically removed. Postoperatively, the patient remained neurologically intact. The treatment was complemented by external whole brain radiation.O tratamento adequado para os pacientes com meningiomas intracranianos continua sendo um desafio, principalmente o de sua variante maligna, a qual tem incidência de 10% a 15%, sem uma certeza do melhor tratamento adjuvante. É indicado o uso da radioterapia externa holocraniana. O uso da quimioterapia tradicional se mostra ineficaz, havendo necessidade de estudos para desenvolver outros agentes quimioterápicos e novos métodos de administração desses agentes no tumor cerebral. A imunoterapia pode ser considerada para os casos de refratariedade aos outros tratamentos adjuvantes. Relatamos o caso de um paciente de 67 anos, com história progressiva de cefaléia, crises convulsivas parciais complexas e agressividade. A investigação radiológica com tomografia computadorizada e ressonância magnética evidenciaram um processo expansivo na região temporoccipital esquerda com contrastação difusa e edema peritumoral importante. Foi realizada craniotomia frontoparietotemporal esquerda com remoção radical da dura-máter infiltrada e do tumor. O paciente evoluiu sem déficit neurológico no pós-operatório. O exame anatomopatológico foi compatível com meningioma maligno do tipo papilar. Foi instituído tratamento complementar com radioterapia externa holocraniana.Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM)Hospital Pró-Cardíaco e Estereolife, Neurocirurgia Estereotáxica e FuncionalFederal University of Rio de JaneiroUNIFESP, EPM, Sao Paulo, BrazilSciELOAcademia Brasileira de Neurologia - ABNEUROUniversidade Federal de São Paulo (UNIFESP)Hospital Pró-Cardíaco e Estereolife, Neurocirurgia Estereotáxica e FuncionalFederal University of Rio de JaneiroFalavigna, Asdrubal [UNIFESP]Santos, José Augusto Nasser dos [UNIFESP]Chimelli, LeilaFerraz, Fernando Antonio Patriani [UNIFESP]Bonatelli, Antonio de Padua Furquim [UNIFESP]2015-06-14T13:29:32Z2015-06-14T13:29:32Z2001-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion939-943application/pdfhttp://dx.doi.org/10.1590/S0004-282X2001000600019Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 59, n. 4, p. 939-943, 2001.10.1590/S0004-282X2001000600019S0004-282X2001000600019.pdf0004-282XS0004-282X2001000600019http://repositorio.unifesp.br/handle/11600/1284engArquivos de Neuro-Psiquiatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-10-07T15:52:26Zoai:repositorio.unifesp.br/:11600/1284Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-10-07T15:52:26Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Anaplastic meningioma: case report
Meningioma anaplásico: relato de caso
title Anaplastic meningioma: case report
spellingShingle Anaplastic meningioma: case report
Falavigna, Asdrubal [UNIFESP]
papillary meningioma
pathology
radiotherapy
chemotherapy
meningeoma papilar
patologia
radioterapia
quimioterapia
title_short Anaplastic meningioma: case report
title_full Anaplastic meningioma: case report
title_fullStr Anaplastic meningioma: case report
title_full_unstemmed Anaplastic meningioma: case report
title_sort Anaplastic meningioma: case report
author Falavigna, Asdrubal [UNIFESP]
author_facet Falavigna, Asdrubal [UNIFESP]
Santos, José Augusto Nasser dos [UNIFESP]
Chimelli, Leila
Ferraz, Fernando Antonio Patriani [UNIFESP]
Bonatelli, Antonio de Padua Furquim [UNIFESP]
author_role author
author2 Santos, José Augusto Nasser dos [UNIFESP]
Chimelli, Leila
Ferraz, Fernando Antonio Patriani [UNIFESP]
Bonatelli, Antonio de Padua Furquim [UNIFESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Hospital Pró-Cardíaco e Estereolife, Neurocirurgia Estereotáxica e Funcional
Federal University of Rio de Janeiro
dc.contributor.author.fl_str_mv Falavigna, Asdrubal [UNIFESP]
Santos, José Augusto Nasser dos [UNIFESP]
Chimelli, Leila
Ferraz, Fernando Antonio Patriani [UNIFESP]
Bonatelli, Antonio de Padua Furquim [UNIFESP]
dc.subject.por.fl_str_mv papillary meningioma
pathology
radiotherapy
chemotherapy
meningeoma papilar
patologia
radioterapia
quimioterapia
topic papillary meningioma
pathology
radiotherapy
chemotherapy
meningeoma papilar
patologia
radioterapia
quimioterapia
description Intracranial meningiomas continue to challenge our best clinical efforts to eliminate them once discovered and deemed appropriate for treatment. Malignant meningiomas constitute 10% to 15% of all meningiomas and limited information exists regarding adjuvant treatment. The external whole brain irradiation is recommended. Traditional chemotherapy has proven ineffective; thus, new chemotherapeutic agents and new methods of delivery should be developed. Immunotherapy may be considered for patients with malignant meningiomas when all others previous treatment have failed. We report a case of anaplastic papillary meningioma. A 67-year-old man presented with partial complex seizures, headache and aggressiveness. A computerized tomography and magnetic resonance image demonstrated a large left temporo-occipital mass with difuse contrast enhancement and extensive surrounding edema. A left temporo-occipital flap was performed. The tumor and the infiltrated dura were radically removed. Postoperatively, the patient remained neurologically intact. The treatment was complemented by external whole brain radiation.
publishDate 2001
dc.date.none.fl_str_mv 2001-12-01
2015-06-14T13:29:32Z
2015-06-14T13:29:32Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0004-282X2001000600019
Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 59, n. 4, p. 939-943, 2001.
10.1590/S0004-282X2001000600019
S0004-282X2001000600019.pdf
0004-282X
S0004-282X2001000600019
http://repositorio.unifesp.br/handle/11600/1284
url http://dx.doi.org/10.1590/S0004-282X2001000600019
http://repositorio.unifesp.br/handle/11600/1284
identifier_str_mv Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 59, n. 4, p. 939-943, 2001.
10.1590/S0004-282X2001000600019
S0004-282X2001000600019.pdf
0004-282X
S0004-282X2001000600019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos de Neuro-Psiquiatria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 939-943
application/pdf
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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