Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements
Autor(a) principal: | |
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Data de Publicação: | 2004 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/27811 http://dx.doi.org/10.1167/iovs.04-0155 |
Resumo: | PURPOSE. To investigate the automatic delineation of the outer limits of the macular neural retina, by using the optical coherence tomography (OCT)-3 built-in software, and to determine its influence in assessing retinal thickness in the normal macula.METHODS. Retrospective analysis of the OCT3 data at a tertiary-care referral center was performed to study the automatic delineation of the outer neural retina boundary generated by the OCT built-in software. in parallel, a cross-sectional study was designed to compare retinal thickness measurements obtained at specific macular regions of nine normal eyes by the automatic measurement tool with those obtained using a manual-caliper-assisted technique.RESULTS. OCT data from 121 eyes were evaluated. Two parallel, linear highly reflective layers (HRL) were visible at the level of the outer retinal boundary in normal macular regions. Disappearance of the inner and maintenance of the outer HRL was noted in the presence of eye conditions affecting the external retinal layers. the automated software delineation for the outer retinal border was primarily guided by the presence of the inner HRL, whereas the correlation of the OCT findings with the expected clinical and angiographic features on eyes presenting specific macular conditions pointed toward a deeper retinal pigment epithelium-retina interface occurring at the level of the outer HRL. There was a statistically significant difference between the retinal thickness in specific normal macular regions obtained by the automatic measurement tool and the caliper-assisted technique in which the outer retinal border delineation was based on the outer HRL (P = 0.008, Wilcoxon signed rank test).CONCLUSIONS. Incorrect delineation of the outer neural retina boundary is occurring with the automated retinal thickness measurement tool of the OCT3 software. At specific regions of the normal macula, retinal thicknesses were significantly underestimated due to such misalignment. |
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Costa, R. A.Calucci, D.Skaf, M.Cardillo, J. A.Castro, J. C.Melo Jr, Luiz Alberto Soares de [UNIFESP]Martins, Maria Cristina [UNIFESP]Kaiser, P. K.Hosp Olhos AraraquaraUniversidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)Cleveland Clin Fdn2016-01-24T12:37:14Z2016-01-24T12:37:14Z2004-07-01Investigative Ophthalmology & Visual Science. Rockville: Assoc Research Vision Ophthalmology Inc, v. 45, n. 7, p. 2399-2406, 2004.0146-0404http://repositorio.unifesp.br/handle/11600/27811http://dx.doi.org/10.1167/iovs.04-015510.1167/iovs.04-0155WOS:000222367900048PURPOSE. To investigate the automatic delineation of the outer limits of the macular neural retina, by using the optical coherence tomography (OCT)-3 built-in software, and to determine its influence in assessing retinal thickness in the normal macula.METHODS. Retrospective analysis of the OCT3 data at a tertiary-care referral center was performed to study the automatic delineation of the outer neural retina boundary generated by the OCT built-in software. in parallel, a cross-sectional study was designed to compare retinal thickness measurements obtained at specific macular regions of nine normal eyes by the automatic measurement tool with those obtained using a manual-caliper-assisted technique.RESULTS. OCT data from 121 eyes were evaluated. Two parallel, linear highly reflective layers (HRL) were visible at the level of the outer retinal boundary in normal macular regions. Disappearance of the inner and maintenance of the outer HRL was noted in the presence of eye conditions affecting the external retinal layers. the automated software delineation for the outer retinal border was primarily guided by the presence of the inner HRL, whereas the correlation of the OCT findings with the expected clinical and angiographic features on eyes presenting specific macular conditions pointed toward a deeper retinal pigment epithelium-retina interface occurring at the level of the outer HRL. There was a statistically significant difference between the retinal thickness in specific normal macular regions obtained by the automatic measurement tool and the caliper-assisted technique in which the outer retinal border delineation was based on the outer HRL (P = 0.008, Wilcoxon signed rank test).CONCLUSIONS. Incorrect delineation of the outer neural retina boundary is occurring with the automated retinal thickness measurement tool of the OCT3 software. At specific regions of the normal macula, retinal thicknesses were significantly underestimated due to such misalignment.Hosp Olhos Araraquara, Retinal Diagnost & Treatment Div, BR-14801350 Araraquara, SP, BrazilHosp Olhos Araraquara, Glaucoma Sect, BR-14801350 Araraquara, SP, BrazilUSP, Inst Fis Sao Carlos, Sao Carlos, SP, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilCleveland Clin Fdn, Cole Eye Inst, Div Ophthalmol, Cleveland, OH 44195 USAUniversidade Federal de São Paulo, EPM, São Paulo, BrazilWeb of Science2399-2406engAssoc Research Vision Ophthalmology IncInvestigative Ophthalmology & Visual ScienceOptical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurementsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/278112022-09-27 10:00:00.262metadata only accessoai:repositorio.unifesp.br:11600/27811Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:24:07.009995Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements |
title |
Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements |
spellingShingle |
Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements Costa, R. A. |
title_short |
Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements |
title_full |
Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements |
title_fullStr |
Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements |
title_full_unstemmed |
Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements |
title_sort |
Optical coherence tomography 3: Delineation of the outer neural retinal boundary and its influence on retinal thickness measurements |
author |
Costa, R. A. |
author_facet |
Costa, R. A. Calucci, D. Skaf, M. Cardillo, J. A. Castro, J. C. Melo Jr, Luiz Alberto Soares de [UNIFESP] Martins, Maria Cristina [UNIFESP] Kaiser, P. K. |
author_role |
author |
author2 |
Calucci, D. Skaf, M. Cardillo, J. A. Castro, J. C. Melo Jr, Luiz Alberto Soares de [UNIFESP] Martins, Maria Cristina [UNIFESP] Kaiser, P. K. |
author2_role |
author author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Hosp Olhos Araraquara Universidade de São Paulo (USP) Universidade Federal de São Paulo (UNIFESP) Cleveland Clin Fdn |
dc.contributor.author.fl_str_mv |
Costa, R. A. Calucci, D. Skaf, M. Cardillo, J. A. Castro, J. C. Melo Jr, Luiz Alberto Soares de [UNIFESP] Martins, Maria Cristina [UNIFESP] Kaiser, P. K. |
description |
PURPOSE. To investigate the automatic delineation of the outer limits of the macular neural retina, by using the optical coherence tomography (OCT)-3 built-in software, and to determine its influence in assessing retinal thickness in the normal macula.METHODS. Retrospective analysis of the OCT3 data at a tertiary-care referral center was performed to study the automatic delineation of the outer neural retina boundary generated by the OCT built-in software. in parallel, a cross-sectional study was designed to compare retinal thickness measurements obtained at specific macular regions of nine normal eyes by the automatic measurement tool with those obtained using a manual-caliper-assisted technique.RESULTS. OCT data from 121 eyes were evaluated. Two parallel, linear highly reflective layers (HRL) were visible at the level of the outer retinal boundary in normal macular regions. Disappearance of the inner and maintenance of the outer HRL was noted in the presence of eye conditions affecting the external retinal layers. the automated software delineation for the outer retinal border was primarily guided by the presence of the inner HRL, whereas the correlation of the OCT findings with the expected clinical and angiographic features on eyes presenting specific macular conditions pointed toward a deeper retinal pigment epithelium-retina interface occurring at the level of the outer HRL. There was a statistically significant difference between the retinal thickness in specific normal macular regions obtained by the automatic measurement tool and the caliper-assisted technique in which the outer retinal border delineation was based on the outer HRL (P = 0.008, Wilcoxon signed rank test).CONCLUSIONS. Incorrect delineation of the outer neural retina boundary is occurring with the automated retinal thickness measurement tool of the OCT3 software. At specific regions of the normal macula, retinal thicknesses were significantly underestimated due to such misalignment. |
publishDate |
2004 |
dc.date.issued.fl_str_mv |
2004-07-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T12:37:14Z |
dc.date.available.fl_str_mv |
2016-01-24T12:37:14Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Investigative Ophthalmology & Visual Science. Rockville: Assoc Research Vision Ophthalmology Inc, v. 45, n. 7, p. 2399-2406, 2004. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/27811 http://dx.doi.org/10.1167/iovs.04-0155 |
dc.identifier.issn.none.fl_str_mv |
0146-0404 |
dc.identifier.doi.none.fl_str_mv |
10.1167/iovs.04-0155 |
dc.identifier.wos.none.fl_str_mv |
WOS:000222367900048 |
identifier_str_mv |
Investigative Ophthalmology & Visual Science. Rockville: Assoc Research Vision Ophthalmology Inc, v. 45, n. 7, p. 2399-2406, 2004. 0146-0404 10.1167/iovs.04-0155 WOS:000222367900048 |
url |
http://repositorio.unifesp.br/handle/11600/27811 http://dx.doi.org/10.1167/iovs.04-0155 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Investigative Ophthalmology & Visual Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
2399-2406 |
dc.publisher.none.fl_str_mv |
Assoc Research Vision Ophthalmology Inc |
publisher.none.fl_str_mv |
Assoc Research Vision Ophthalmology Inc |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
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1783460286186913792 |