Interação medicamentosa no serviço de emergência

• Autor(a) principal: Okuno, Meiry Fernanda Pinto [UNIFESP]
• Data de Publicação: 2013
• Outros Autores: Cintra, Raíssa Silveira [UNIFESP], Vancini-campanharo, Cássia Regina [UNIFESP], Batista, Ruth Ester Assayag [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S1679-45082013000400010; http://repositorio.unifesp.br/handle/11600/8081
• topic: Drug interactions; Drugs incompatibility; Patient safety; Interações de medicamentos; Incompatibilidade de medicamentos; Segurança do paciente

OBJECTIVE: To identify the occurrence of potential drug interactions in prescriptions for adult patients admitted to the Emergency Department of Hospital São Paulo. METHODS: A cross-sectional and descriptive study. Its sample consisted of 200 medical prescriptions. The analysis of drug interactions was performed using the Drugs.com database, where they are classified according to severity of interaction as severe, moderate, mild and without interaction. RESULTS: The number of drugs in prescriptions ranged from 2 to 19, and the average per prescription was 4.97 drugs. A total of 526 potential drug interactions were identified in 159 prescriptions (79.5%); in that, 109 were severe, 354 moderate, 63 mild interactions, and 41 showed no interaction. CONCLUSION: This study demonstrated potential drug interactions in 79.5% of prescriptions examined in the Emergency Department. Drug interactions can occur at any time when using medications and, during this working process, the nursing staff is involved in several steps. Therefore, training the nursing staff for the rational use of drugs can increase safety of care delivered to patients.