Incidence of bloodstream infection among patients on hemodialysis by central venous catheter

• Autor(a) principal: Grothe, Cibele [UNIFESP]
• Data de Publicação: 2010
• Outros Autores: Belasco, Angélica Gonçalves Silva [UNIFESP], Bittencourt, Ana Rita de Cássia [UNIFESP], Vianna, Lucila Amaral Carneiro [UNIFESP], Sesso, Ricardo de Castro Cintra [UNIFESP], Barbosa, Dulce Aparecida [UNIFESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0104-11692010000100012; http://repositorio.unifesp.br/handle/11600/5595
• topic: Catheterization; Renal Dialysis; Staphylococcus aureus; Cateterismo; Diálise Renal; Staphylococcus aureus

This study evaluated the incidence and risk factors of bloodstream infection (BSI) among patients with a double-lumen central venous catheter (CVC) for hemodialysis (HD) and identified the microorganisms isolated from the bloodstream. A follow-up included all patients (n=156) who underwent hemodialysis by double-lumen CVC at the Federal University of São Paulo - UNIFESP, Brazil, over a one-year period. From the group of patients, 94 presented BSI, of whom 39 had positive cultures at the central venous catheter insertion location. Of the 128 microorganisms isolated from the bloodstream, 53 were S. aureus, 30 were methicillin-sensitive and 23 were methicillin-resistant. Complications related to BSI included 35 cases of septicemia and 27 cases of endocarditis, of which 15 cases progressed to death. The incidence of BSI among these patients was shown to be very high, and this BSI progressed rapidly to the condition of severe infection with a high mortality rate.