Quality of life related to surgical treatment in patients with temporal lobe epilepsy due to mesial temporal sclerosis

• Autor(a) principal: Alonso, Neide Barreira [UNIFESP]
• Data de Publicação: 2006
• Outros Autores: Silva, Tatiana Indelicato Da [UNIFESP], Westphal-guitti, Ana Carolina [UNIFESP], Azevedo, Auro Mauro [UNIFESP], Caboclo, Luís Otávio Sales Ferreira [UNIFESP], Sakamoto, Américo Ceiki [UNIFESP], Yacubian, Elza Márcia Targas [UNIFESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• dARK ID: ark:/48912/001300000cmq3
• DOI: 10.1590/S1676-26492006000700009
• Texto Completo: http://dx.doi.org/10.1590/S1676-26492006000700009; http://repositorio.unifesp.br/handle/11600/3341
• topic: temporal lobe epilepsy; surgical treatment; quality of life; Epilepsy Surgery Inventory (ESI-55); epilepsia do lobo temporal; tratamento cirúrgico; Epilepsy Surgery Inventory (ESI-55); qualidade de vida

INTRODUCTION: Surgery is widely accepted as a modality of treatment for medically intractable seizures and the main goals of surgery as reduction or elimination of seizures without significant compromise in neurological function and improving QOL. PURPOSE: To assess QOL pre- and post-surgery in a sample of patients with temporal lobe epilepsy (TLE) due to mesial temporal sclerosis (MTS). METHODS: Thirty-five consenting subjects who had undergone corticoamygdalo-hipocampetomy were included in this study. They answered the ESI-55 before and six months after surgical treatment. Analyses of Variance (ANOVA) was used to study the changes in QOL and we also determined the effect-size of the sample. RESULTS: After surgical treatment 18 (51%) subjects were seizure free, 10 (29%) had only auras and seven (20%) had partial seizures. The post-operative mean scores were higher than pre-operative scores, except for Cognitive Function and Limitation due to Cognitive Problems in the group with seizures. A significant improvement in QOL post-surgery was observed in the domains Health-Perception (1.24), Emotional-Well-being (1.32) and Energy/Fatigue (1.43). CONCLUSION: A long-term follow-up is necessary to identify meanigful changes after the surgery.