Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
Autor(a) principal: | |
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Data de Publicação: | 1997 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S1516-31801997000100003 http://repositorio.unifesp.br/handle/11600/464 |
Resumo: | INTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men. |
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Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirusPeniscopypapillomavirusHPVcolposcopyINTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men.INTRODUÇÃO: A infecção genital masculina pelo papilomavírus humano tem especial importância, pois é, freqüentemente, assintomática. Na maioria dos casos, o indivíduo não apresenta lesão clínica. Por isso, os homens passam a ser encarados como importante reservatório do vírus, exercendo papel especial na transmissão e perpetuação da doença. PACIENTES E MÉTODOS: No presente estudo clínico do tipo prospectivo, foram avaliados 190 parceiros de mulheres com infecção genital por papilomavírus humano, associada ou não à neoplasia intra-epitelial cervical. Todos os pacientes desconheciam ou negavam a presença de lesão genital. RESULTADOS: A citologia uretral exibiu coilocitose em nove casos (4,7%) e três (1,6%) na coroa da glande e prepúcio distal. A peniscopia, após a aplicação de ácido acético a 5%, revelou lesões brancas em 97,9% dos pacientes. A solução do azul de toluidina corou a maior parte das lesões observadas, Pelo menos um fragmento revelou coilocitose quando do estudo histopatológico em 97 casos (51,05%). CONCLUSÃO: Os três métodos se complementam, permitindo diagnóstico mais preciso dessa infecção no homem.Escola Paulista de Medicina Department of Obstetrics and GynecologyEscola Paulista de Medicina Department of Pathological AnatomyUNIFESP, EPM, Department of Obstetrics and GynecologyEscola Paulista de Medicina Department of Pathological AnatomySciELOAssociação Paulista de Medicina - APMUniversidade Federal de São Paulo (UNIFESP)Nicolau, Sergio Mancini [UNIFESP]Martins, Nelson Valente [UNIFESP]Ferraz, Paulo Eduardo [UNIFESP]Stávale, João Norberto [UNIFESP]Goncalves, Wagner Jose [UNIFESP]Baracat, Edmund Chada [UNIFESP]Lima, Geraldo Rodrigues de [UNIFESP]2015-06-14T13:24:34Z2015-06-14T13:24:34Z1997-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1330-1335application/pdfhttp://dx.doi.org/10.1590/S1516-31801997000100003São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 1, p. 1330-1335, 1997.10.1590/S1516-31801997000100003S1516-31801997000100003.pdf1516-3180S1516-31801997000100003http://repositorio.unifesp.br/handle/11600/464engSão Paulo Medical Journalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T06:35:27Zoai:repositorio.unifesp.br/:11600/464Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T06:35:27Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus |
title |
Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus |
spellingShingle |
Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus Nicolau, Sergio Mancini [UNIFESP] Peniscopy papillomavirus HPV colposcopy |
title_short |
Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus |
title_full |
Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus |
title_fullStr |
Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus |
title_full_unstemmed |
Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus |
title_sort |
Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus |
author |
Nicolau, Sergio Mancini [UNIFESP] |
author_facet |
Nicolau, Sergio Mancini [UNIFESP] Martins, Nelson Valente [UNIFESP] Ferraz, Paulo Eduardo [UNIFESP] Stávale, João Norberto [UNIFESP] Goncalves, Wagner Jose [UNIFESP] Baracat, Edmund Chada [UNIFESP] Lima, Geraldo Rodrigues de [UNIFESP] |
author_role |
author |
author2 |
Martins, Nelson Valente [UNIFESP] Ferraz, Paulo Eduardo [UNIFESP] Stávale, João Norberto [UNIFESP] Goncalves, Wagner Jose [UNIFESP] Baracat, Edmund Chada [UNIFESP] Lima, Geraldo Rodrigues de [UNIFESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Nicolau, Sergio Mancini [UNIFESP] Martins, Nelson Valente [UNIFESP] Ferraz, Paulo Eduardo [UNIFESP] Stávale, João Norberto [UNIFESP] Goncalves, Wagner Jose [UNIFESP] Baracat, Edmund Chada [UNIFESP] Lima, Geraldo Rodrigues de [UNIFESP] |
dc.subject.por.fl_str_mv |
Peniscopy papillomavirus HPV colposcopy |
topic |
Peniscopy papillomavirus HPV colposcopy |
description |
INTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men. |
publishDate |
1997 |
dc.date.none.fl_str_mv |
1997-02-01 2015-06-14T13:24:34Z 2015-06-14T13:24:34Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1516-31801997000100003 São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 1, p. 1330-1335, 1997. 10.1590/S1516-31801997000100003 S1516-31801997000100003.pdf 1516-3180 S1516-31801997000100003 http://repositorio.unifesp.br/handle/11600/464 |
url |
http://dx.doi.org/10.1590/S1516-31801997000100003 http://repositorio.unifesp.br/handle/11600/464 |
identifier_str_mv |
São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 1, p. 1330-1335, 1997. 10.1590/S1516-31801997000100003 S1516-31801997000100003.pdf 1516-3180 S1516-31801997000100003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
São Paulo Medical Journal |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1330-1335 application/pdf |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268325288476672 |