Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus

Detalhes bibliográficos
Autor(a) principal: Nicolau, Sergio Mancini [UNIFESP]
Data de Publicação: 1997
Outros Autores: Martins, Nelson Valente [UNIFESP], Ferraz, Paulo Eduardo [UNIFESP], Stávale, João Norberto [UNIFESP], Goncalves, Wagner Jose [UNIFESP], Baracat, Edmund Chada [UNIFESP], Lima, Geraldo Rodrigues de [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S1516-31801997000100003
http://repositorio.unifesp.br/handle/11600/464
Resumo: INTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men.
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spelling Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirusPeniscopypapillomavirusHPVcolposcopyINTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men.INTRODUÇÃO: A infecção genital masculina pelo papilomavírus humano tem especial importância, pois é, freqüentemente, assintomática. Na maioria dos casos, o indivíduo não apresenta lesão clínica. Por isso, os homens passam a ser encarados como importante reservatório do vírus, exercendo papel especial na transmissão e perpetuação da doença. PACIENTES E MÉTODOS: No presente estudo clínico do tipo prospectivo, foram avaliados 190 parceiros de mulheres com infecção genital por papilomavírus humano, associada ou não à neoplasia intra-epitelial cervical. Todos os pacientes desconheciam ou negavam a presença de lesão genital. RESULTADOS: A citologia uretral exibiu coilocitose em nove casos (4,7%) e três (1,6%) na coroa da glande e prepúcio distal. A peniscopia, após a aplicação de ácido acético a 5%, revelou lesões brancas em 97,9% dos pacientes. A solução do azul de toluidina corou a maior parte das lesões observadas, Pelo menos um fragmento revelou coilocitose quando do estudo histopatológico em 97 casos (51,05%). CONCLUSÃO: Os três métodos se complementam, permitindo diagnóstico mais preciso dessa infecção no homem.Escola Paulista de Medicina Department of Obstetrics and GynecologyEscola Paulista de Medicina Department of Pathological AnatomyUNIFESP, EPM, Department of Obstetrics and GynecologyEscola Paulista de Medicina Department of Pathological AnatomySciELOAssociação Paulista de Medicina - APMUniversidade Federal de São Paulo (UNIFESP)Nicolau, Sergio Mancini [UNIFESP]Martins, Nelson Valente [UNIFESP]Ferraz, Paulo Eduardo [UNIFESP]Stávale, João Norberto [UNIFESP]Goncalves, Wagner Jose [UNIFESP]Baracat, Edmund Chada [UNIFESP]Lima, Geraldo Rodrigues de [UNIFESP]2015-06-14T13:24:34Z2015-06-14T13:24:34Z1997-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1330-1335application/pdfhttp://dx.doi.org/10.1590/S1516-31801997000100003São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 1, p. 1330-1335, 1997.10.1590/S1516-31801997000100003S1516-31801997000100003.pdf1516-3180S1516-31801997000100003http://repositorio.unifesp.br/handle/11600/464engSão Paulo Medical Journalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T06:35:27Zoai:repositorio.unifesp.br/:11600/464Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T06:35:27Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
title Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
spellingShingle Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
Nicolau, Sergio Mancini [UNIFESP]
Peniscopy
papillomavirus
HPV
colposcopy
title_short Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
title_full Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
title_fullStr Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
title_full_unstemmed Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
title_sort Importance of peniscopy, oncologic cytology and histopathology in the diagnosis of penile infection by human papillomavirus
author Nicolau, Sergio Mancini [UNIFESP]
author_facet Nicolau, Sergio Mancini [UNIFESP]
Martins, Nelson Valente [UNIFESP]
Ferraz, Paulo Eduardo [UNIFESP]
Stávale, João Norberto [UNIFESP]
Goncalves, Wagner Jose [UNIFESP]
Baracat, Edmund Chada [UNIFESP]
Lima, Geraldo Rodrigues de [UNIFESP]
author_role author
author2 Martins, Nelson Valente [UNIFESP]
Ferraz, Paulo Eduardo [UNIFESP]
Stávale, João Norberto [UNIFESP]
Goncalves, Wagner Jose [UNIFESP]
Baracat, Edmund Chada [UNIFESP]
Lima, Geraldo Rodrigues de [UNIFESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Nicolau, Sergio Mancini [UNIFESP]
Martins, Nelson Valente [UNIFESP]
Ferraz, Paulo Eduardo [UNIFESP]
Stávale, João Norberto [UNIFESP]
Goncalves, Wagner Jose [UNIFESP]
Baracat, Edmund Chada [UNIFESP]
Lima, Geraldo Rodrigues de [UNIFESP]
dc.subject.por.fl_str_mv Peniscopy
papillomavirus
HPV
colposcopy
topic Peniscopy
papillomavirus
HPV
colposcopy
description INTRODUCTION: Male genital infection by human papillomavirus is of particular importance since it is often asymptomatic. The patient generally presents no clinical lesion. Therefore, men represent an important reservoir of virus, playing a special role in the transmission and perpetuation of the disease. PATIENTS AND METHODS: In the present prospective clinical trial study, 190 sex partners of women with genital infection by human papillomavirus, associated or not with cervical intraepithelial neoplasia, were investigated. All patients were unaware of or denied the presence of a genital lesion. RESULTS: Cytologic examination revealed koilocytosis in 9 cases (4.7%) in the urethra and in 3 cases (1.6%) in the corona of the glans and the distal prepuce. Peniscopy with the previous use of 5% acetic acid revealed white lesions in 97.9% of the patients. Toluidine blue stained most of the lesions. At least one fragment revealed koilocytosis in the histopathologic study of 97 cases (51.05%). CONCLUSION: The three methods complement one another, allowing a more precise diagnosis of this infection in men.
publishDate 1997
dc.date.none.fl_str_mv 1997-02-01
2015-06-14T13:24:34Z
2015-06-14T13:24:34Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1516-31801997000100003
São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 1, p. 1330-1335, 1997.
10.1590/S1516-31801997000100003
S1516-31801997000100003.pdf
1516-3180
S1516-31801997000100003
http://repositorio.unifesp.br/handle/11600/464
url http://dx.doi.org/10.1590/S1516-31801997000100003
http://repositorio.unifesp.br/handle/11600/464
identifier_str_mv São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 1, p. 1330-1335, 1997.
10.1590/S1516-31801997000100003
S1516-31801997000100003.pdf
1516-3180
S1516-31801997000100003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv São Paulo Medical Journal
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1330-1335
application/pdf
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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