Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis
Autor(a) principal: | |
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Data de Publicação: | 2006 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
dARK ID: | ark:/48912/00130000192zg |
Texto Completo: | http://dx.doi.org/10.1590/S1413-86702006000100012 http://repositorio.unifesp.br/handle/11600/2920 |
Resumo: | Three HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes. This finding raises the question of potential mechanisms involved in the activation or loss of T-cells in disseminated tuberculosis. |
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Repositório Institucional da UNIFESP |
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Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosisMycobacterium tuberculosisdisseminated tuberculosislymphocytecellular activationThree HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes. This finding raises the question of potential mechanisms involved in the activation or loss of T-cells in disseminated tuberculosis.Federal University of São Paulo Infectious Diseases DivisionUNIFESP, Infectious Diseases DivisionSciELOBrazilian Society of Infectious DiseasesUniversidade Federal de São Paulo (UNIFESP)Rodrigues, Denise do Socorro da Silva [UNIFESP]Salomão, Reinaldo [UNIFESP]Kallas, Esper Georges [UNIFESP]2015-06-14T13:31:58Z2015-06-14T13:31:58Z2006-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion59-61application/pdfhttp://dx.doi.org/10.1590/S1413-86702006000100012Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 10, n. 1, p. 59-61, 2006.10.1590/S1413-86702006000100012S1413-86702006000100012.pdf1413-8670S1413-86702006000100012http://repositorio.unifesp.br/handle/11600/2920ark:/48912/00130000192zgengBrazilian Journal of Infectious Diseasesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-30T14:49:43Zoai:repositorio.unifesp.br/:11600/2920Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T21:04:53.182047Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis |
title |
Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis |
spellingShingle |
Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis Rodrigues, Denise do Socorro da Silva [UNIFESP] Mycobacterium tuberculosis disseminated tuberculosis lymphocyte cellular activation |
title_short |
Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis |
title_full |
Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis |
title_fullStr |
Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis |
title_full_unstemmed |
Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis |
title_sort |
Profound peripheral T-lymphocyte depletion and activation in disseminated tuberculosis |
author |
Rodrigues, Denise do Socorro da Silva [UNIFESP] |
author_facet |
Rodrigues, Denise do Socorro da Silva [UNIFESP] Salomão, Reinaldo [UNIFESP] Kallas, Esper Georges [UNIFESP] |
author_role |
author |
author2 |
Salomão, Reinaldo [UNIFESP] Kallas, Esper Georges [UNIFESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Rodrigues, Denise do Socorro da Silva [UNIFESP] Salomão, Reinaldo [UNIFESP] Kallas, Esper Georges [UNIFESP] |
dc.subject.por.fl_str_mv |
Mycobacterium tuberculosis disseminated tuberculosis lymphocyte cellular activation |
topic |
Mycobacterium tuberculosis disseminated tuberculosis lymphocyte cellular activation |
description |
Three HIV-1-seronegative patients with disseminated tuberculosis presented significant depletion of T-cell counts, in CD4+ and/or CD8+ cells, associated with increased expression of activation marker CD38 on CD8+ T-lymphocytes. This finding raises the question of potential mechanisms involved in the activation or loss of T-cells in disseminated tuberculosis. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006-02-01 2015-06-14T13:31:58Z 2015-06-14T13:31:58Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1413-86702006000100012 Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 10, n. 1, p. 59-61, 2006. 10.1590/S1413-86702006000100012 S1413-86702006000100012.pdf 1413-8670 S1413-86702006000100012 http://repositorio.unifesp.br/handle/11600/2920 |
dc.identifier.dark.fl_str_mv |
ark:/48912/00130000192zg |
url |
http://dx.doi.org/10.1590/S1413-86702006000100012 http://repositorio.unifesp.br/handle/11600/2920 |
identifier_str_mv |
Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 10, n. 1, p. 59-61, 2006. 10.1590/S1413-86702006000100012 S1413-86702006000100012.pdf 1413-8670 S1413-86702006000100012 ark:/48912/00130000192zg |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Infectious Diseases |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
59-61 application/pdf |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1818602598714834944 |