Densidade mineral óssea de adolescentes com sobrepeso e obesidade

Detalhes bibliográficos
Autor(a) principal: Cobayashi, Fernanda [UNIFESP]
Data de Publicação: 2005
Outros Autores: Lopes, Luiz A. [UNIFESP], Taddei, Jose Augusto de Aguiar Carrazedo [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0021-75572005000500013
http://repositorio.unifesp.br/handle/11600/2607
Resumo: OBJECTIVE: to study bone density as a concomitant factor for obesity in post-pubertal adolescents, controlling for other variables that may interfere in such a relation. METHODS: Study comprising 83 overweight and obese adolescents (BMI > P85) and 89 non obese ones (P5 < BMI < P85). Cases and controls were selected out of 1,420 students (aged 14-19) from a public school in the city of São Paulo. The bone mineral density of the lumbar spine (L2-L4 in g/cm²) was assessed by dual-energy x-ray absorptiometry (LUNAR DPX-L). The variable bone density was dichotomized using 1.194 g/cm² as cutoff point. Bivariate analyses were conducted considering the prevalence of overweight and obesity followed by multivariate analysis (logistic regression) according to a hierarchical conceptual model. RESULTS: The prevalence of bone density above the median was twice more frequent among cases (69.3%) than among controls (32.1%). In the bivariate analysis such prevalence resulted in an odds ratio (OR) of 4.78. The logistic regression model showed that the association between obesity and mineral density is yet more intense with an OR of 6.65 after the control of variables related to sedentary lifestyle and intake of milk and dairy products. CONCLUSION: Obese and overweight adolescents in the final stages of sexual maturity presented higher bone mineral density in relation to their normal-weight counterparts; however, cohort studies will be necessary to evaluate the influence of such characteristic on bone resistance in adulthood and, consequently, on the incidence of osteopenia and osteoporosis at older ages.
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spelling Densidade mineral óssea de adolescentes com sobrepeso e obesidadeBone mineral density in overweight and obese adolescentsObesitybone densityadolescentosteoporosisObesidadedensidade ósseaadolescenteosteoporoseOBJECTIVE: to study bone density as a concomitant factor for obesity in post-pubertal adolescents, controlling for other variables that may interfere in such a relation. METHODS: Study comprising 83 overweight and obese adolescents (BMI > P85) and 89 non obese ones (P5 < BMI < P85). Cases and controls were selected out of 1,420 students (aged 14-19) from a public school in the city of São Paulo. The bone mineral density of the lumbar spine (L2-L4 in g/cm²) was assessed by dual-energy x-ray absorptiometry (LUNAR DPX-L). The variable bone density was dichotomized using 1.194 g/cm² as cutoff point. Bivariate analyses were conducted considering the prevalence of overweight and obesity followed by multivariate analysis (logistic regression) according to a hierarchical conceptual model. RESULTS: The prevalence of bone density above the median was twice more frequent among cases (69.3%) than among controls (32.1%). In the bivariate analysis such prevalence resulted in an odds ratio (OR) of 4.78. The logistic regression model showed that the association between obesity and mineral density is yet more intense with an OR of 6.65 after the control of variables related to sedentary lifestyle and intake of milk and dairy products. CONCLUSION: Obese and overweight adolescents in the final stages of sexual maturity presented higher bone mineral density in relation to their normal-weight counterparts; however, cohort studies will be necessary to evaluate the influence of such characteristic on bone resistance in adulthood and, consequently, on the incidence of osteopenia and osteoporosis at older ages.OBJETIVO: Estudar a densidade óssea como fator concomitante da obesidade em adolescentes pós-púberes, controlando outras variáveis que possam interferir nessa relação. MÉTODOS: Estudo com 83 sobrepesos e obesos (IMC > P85) e 89 não obesos (P5 < IMC < P85). Casos e controles foram selecionados entre 1420 estudantes (14-19 anos) de escola pública na cidade de São Paulo. A densidade mineral óssea de coluna (L2-L4 em g/cm²) foi avaliada por meio de densitometria de duplo feixe de raios X (LUNAR® DPX-L). A variável densidade óssea foi categorizada utilizando a mediana 1,194 g/cm² como ponto de corte. Foram realizadas análises bivariadas, observando-se a prevalência de sobrepeso e obesidade. Em seguida, procedeu-se à análise multivariada (regressão logística), de acordo com um modelo conceitual hierárquico. RESULTADOS: A prevalência de densidade óssea acima da mediana foi duas vezes mais freqüente entre os casos (69,3%) do que entre os controles (32,1%). Na análise bivariada, tais prevalências resultaram em odds ratio (OR) de 4,78. O modelo de regressão logística mostrou que a associação entre obesidade e densidade mineral é ainda mais intensa com OR de 6,65, após o controle das variáveis relacionadas ao sedentarismo e ao consumo de leite e derivados. CONCLUSÃO: Observou-se, neste estudo, que adolescentes com sobrepeso e obesidade nos estadios finais da maturação sexual apresentaram maior densidade mineral óssea com relação aos seus pares eutróficos. No entanto, estudos de coorte serão necessários para avaliar a influência dessa característica sobre a resistência óssea na vida adulta e, conseqüentemente, sobre a incidência de osteopenia e osteoporose em faixas etárias mais avançadas.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de PediatriaUniversidade de Santo AmaroUNIFESP-EPM Departamento de PediatriaUNIFESP, EPM, Depto. de PediatriaUNIFESP, EPM Depto. de PediatriaSciELOSociedade Brasileira de PediatriaUniversidade Federal de São Paulo (UNIFESP)Universidade de Santo AmaroCobayashi, Fernanda [UNIFESP]Lopes, Luiz A. [UNIFESP]Taddei, Jose Augusto de Aguiar Carrazedo [UNIFESP]2015-06-14T13:31:40Z2015-06-14T13:31:40Z2005-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion337-342application/pdfhttp://dx.doi.org/10.1590/S0021-75572005000500013Jornal de Pediatria. Sociedade Brasileira de Pediatria, v. 81, n. 4, p. 337-342, 2005.10.1590/S0021-75572005000500013S0021-75572005000500013.pdf0021-7557S0021-75572005000500013http://repositorio.unifesp.br/handle/11600/2607porJornal de Pediatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-03T17:26:00Zoai:repositorio.unifesp.br/:11600/2607Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-03T17:26Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Densidade mineral óssea de adolescentes com sobrepeso e obesidade
Bone mineral density in overweight and obese adolescents
title Densidade mineral óssea de adolescentes com sobrepeso e obesidade
spellingShingle Densidade mineral óssea de adolescentes com sobrepeso e obesidade
Cobayashi, Fernanda [UNIFESP]
Obesity
bone density
adolescent
osteoporosis
Obesidade
densidade óssea
adolescente
osteoporose
title_short Densidade mineral óssea de adolescentes com sobrepeso e obesidade
title_full Densidade mineral óssea de adolescentes com sobrepeso e obesidade
title_fullStr Densidade mineral óssea de adolescentes com sobrepeso e obesidade
title_full_unstemmed Densidade mineral óssea de adolescentes com sobrepeso e obesidade
title_sort Densidade mineral óssea de adolescentes com sobrepeso e obesidade
author Cobayashi, Fernanda [UNIFESP]
author_facet Cobayashi, Fernanda [UNIFESP]
Lopes, Luiz A. [UNIFESP]
Taddei, Jose Augusto de Aguiar Carrazedo [UNIFESP]
author_role author
author2 Lopes, Luiz A. [UNIFESP]
Taddei, Jose Augusto de Aguiar Carrazedo [UNIFESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Universidade de Santo Amaro
dc.contributor.author.fl_str_mv Cobayashi, Fernanda [UNIFESP]
Lopes, Luiz A. [UNIFESP]
Taddei, Jose Augusto de Aguiar Carrazedo [UNIFESP]
dc.subject.por.fl_str_mv Obesity
bone density
adolescent
osteoporosis
Obesidade
densidade óssea
adolescente
osteoporose
topic Obesity
bone density
adolescent
osteoporosis
Obesidade
densidade óssea
adolescente
osteoporose
description OBJECTIVE: to study bone density as a concomitant factor for obesity in post-pubertal adolescents, controlling for other variables that may interfere in such a relation. METHODS: Study comprising 83 overweight and obese adolescents (BMI > P85) and 89 non obese ones (P5 < BMI < P85). Cases and controls were selected out of 1,420 students (aged 14-19) from a public school in the city of São Paulo. The bone mineral density of the lumbar spine (L2-L4 in g/cm²) was assessed by dual-energy x-ray absorptiometry (LUNAR DPX-L). The variable bone density was dichotomized using 1.194 g/cm² as cutoff point. Bivariate analyses were conducted considering the prevalence of overweight and obesity followed by multivariate analysis (logistic regression) according to a hierarchical conceptual model. RESULTS: The prevalence of bone density above the median was twice more frequent among cases (69.3%) than among controls (32.1%). In the bivariate analysis such prevalence resulted in an odds ratio (OR) of 4.78. The logistic regression model showed that the association between obesity and mineral density is yet more intense with an OR of 6.65 after the control of variables related to sedentary lifestyle and intake of milk and dairy products. CONCLUSION: Obese and overweight adolescents in the final stages of sexual maturity presented higher bone mineral density in relation to their normal-weight counterparts; however, cohort studies will be necessary to evaluate the influence of such characteristic on bone resistance in adulthood and, consequently, on the incidence of osteopenia and osteoporosis at older ages.
publishDate 2005
dc.date.none.fl_str_mv 2005-08-01
2015-06-14T13:31:40Z
2015-06-14T13:31:40Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0021-75572005000500013
Jornal de Pediatria. Sociedade Brasileira de Pediatria, v. 81, n. 4, p. 337-342, 2005.
10.1590/S0021-75572005000500013
S0021-75572005000500013.pdf
0021-7557
S0021-75572005000500013
http://repositorio.unifesp.br/handle/11600/2607
url http://dx.doi.org/10.1590/S0021-75572005000500013
http://repositorio.unifesp.br/handle/11600/2607
identifier_str_mv Jornal de Pediatria. Sociedade Brasileira de Pediatria, v. 81, n. 4, p. 337-342, 2005.
10.1590/S0021-75572005000500013
S0021-75572005000500013.pdf
0021-7557
S0021-75572005000500013
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Jornal de Pediatria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 337-342
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Pediatria
publisher.none.fl_str_mv Sociedade Brasileira de Pediatria
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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