Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira

Detalhes bibliográficos
Autor(a) principal: Siqueira, Antonela F. A. [UNIFESP]
Data de Publicação: 2008
Outros Autores: Harima, Helena A. [UNIFESP], Osiro, Katsumi [UNIFESP], Hirai, Amélia Toyomi [UNIFESP], Gimeno, Suely Godoy Agostinho [UNIFESP], Ferreira, Sandra Roberta Gouvea [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0004-27302008000100007
http://repositorio.unifesp.br/handle/11600/4240
Resumo: High prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged >30 years. Hypercholesterolemia was defined as serum cholesterol > 240 mg/dL, hypertriglyceridemia as values > 150 mg/dL and low-HDL-C as values <40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7±196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1- 26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total / HDL-cholesterol ratio was lower in women (4.23 ± 0.68 vs. 4.40 ± 0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health.
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spelling Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileiraLipid profile disturbances are highly prevalent in Japanese-BraziliansDyslipidemiasJapanese-BraziliansDiabetesCardiometabolic riskDislipidemiasNipo-brasileirosDiabetesRisco cardiometabólicoHigh prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged >30 years. Hypercholesterolemia was defined as serum cholesterol > 240 mg/dL, hypertriglyceridemia as values > 150 mg/dL and low-HDL-C as values <40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7±196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1- 26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total / HDL-cholesterol ratio was lower in women (4.23 ± 0.68 vs. 4.40 ± 0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health.Alta prevalência de diabetes em população nipo-brasileira de Bauru/SP foi previamente relatada. Visando a complementar a avaliação do risco cardiometabólico, este estudo analisou distúrbios no perfil lipídico de 1.330 nipo-brasileiros (46% homens) > 30 anos. Definiu-se hipercolesterolemia por níveis de colesterol total > 240 mg/dL; hipertrigliceridemia por valores > 150 mg/dL e HDL-colesterol baixo por valores < 40 mg/dL e < 50 mg/dL para homens e mulheres, respectivamente. A prevalência desses distúrbios foi comparada pelo qui-quadrado, estratificando-se por sexos e categorias glicêmicas. As médias dos lipídeos e lipoproteínas foram comparadas entre sexos pelo teste t de Student. A prevalência de hipertrigliceridemia foi de 66,0% (IC95%:63,5 - 68,5%), sendo mais comum em homens e aumentando com a piora da categoria glicêmica; a trigliceridemia média foi 235,7 ± 196,3 mg/dL. A prevalência de hipercolesterolemia foi 24,4% (IC95%:22,1 - 26,7%); HDL-C baixo foi observado em 43,0% (IC95%:39,4 - 46,6%] das mulheres e 17,5% (IC95%:14,5 - 20,5%) dos homens, porém a razão colesterol total/HDL-C foi menor em mulheres (4,23 ± 0,68 vs. 4,40 ± 0,73; p < 0,001). Em nipo-brasileiros, a hipertrigliceridemia é a anormalidade lipídica mais comum, em concordância com a elevada prevalência de diabetes. Os homens apresentaram pior perfil lipídico que as mulheres. Sugere-se que hábitos de vida ocidental possam estar deteriorando a saúde desses indivíduos.Universidade Federal de São Paulo (UNIFESP) EPM Departamento de MedicinaUniversidade Federal de São Paulo (UNIFESP) EPM Departamento de Medicina PreventivaUniversidade de São Paulo Faculdade de Saúde Pública Departamento de NutriçãoJapanese-Brazilian Diabetes Study GroupUNIFESP, EPM, Depto. de MedicinaUNIFESP, EPM, Depto. de Medicina PreventivaSciELOFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Sociedade Brasileira de Endocrinologia e MetabologiaUniversidade Federal de São Paulo (UNIFESP)Universidade de São Paulo (USP)Japanese-Brazilian Diabetes Study GroupSiqueira, Antonela F. A. [UNIFESP]Harima, Helena A. [UNIFESP]Osiro, Katsumi [UNIFESP]Hirai, Amélia Toyomi [UNIFESP]Gimeno, Suely Godoy Agostinho [UNIFESP]Ferreira, Sandra Roberta Gouvea [UNIFESP]2015-06-14T13:38:24Z2015-06-14T13:38:24Z2008-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion40-46application/pdfhttp://dx.doi.org/10.1590/S0004-27302008000100007Arquivos Brasileiros de Endocrinologia & Metabologia. Sociedade Brasileira de Endocrinologia e Metabologia, v. 52, n. 1, p. 40-46, 2008.10.1590/S0004-27302008000100007S0004-27302008000100007.pdf0004-2730S0004-27302008000100007http://repositorio.unifesp.br/handle/11600/4240porArquivos Brasileiros de Endocrinologia & Metabologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T09:58:26Zoai:repositorio.unifesp.br/:11600/4240Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T09:58:26Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
Lipid profile disturbances are highly prevalent in Japanese-Brazilians
title Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
spellingShingle Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
Siqueira, Antonela F. A. [UNIFESP]
Dyslipidemias
Japanese-Brazilians
Diabetes
Cardiometabolic risk
Dislipidemias
Nipo-brasileiros
Diabetes
Risco cardiometabólico
title_short Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
title_full Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
title_fullStr Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
title_full_unstemmed Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
title_sort Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
author Siqueira, Antonela F. A. [UNIFESP]
author_facet Siqueira, Antonela F. A. [UNIFESP]
Harima, Helena A. [UNIFESP]
Osiro, Katsumi [UNIFESP]
Hirai, Amélia Toyomi [UNIFESP]
Gimeno, Suely Godoy Agostinho [UNIFESP]
Ferreira, Sandra Roberta Gouvea [UNIFESP]
author_role author
author2 Harima, Helena A. [UNIFESP]
Osiro, Katsumi [UNIFESP]
Hirai, Amélia Toyomi [UNIFESP]
Gimeno, Suely Godoy Agostinho [UNIFESP]
Ferreira, Sandra Roberta Gouvea [UNIFESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Universidade de São Paulo (USP)
Japanese-Brazilian Diabetes Study Group
dc.contributor.author.fl_str_mv Siqueira, Antonela F. A. [UNIFESP]
Harima, Helena A. [UNIFESP]
Osiro, Katsumi [UNIFESP]
Hirai, Amélia Toyomi [UNIFESP]
Gimeno, Suely Godoy Agostinho [UNIFESP]
Ferreira, Sandra Roberta Gouvea [UNIFESP]
dc.subject.por.fl_str_mv Dyslipidemias
Japanese-Brazilians
Diabetes
Cardiometabolic risk
Dislipidemias
Nipo-brasileiros
Diabetes
Risco cardiometabólico
topic Dyslipidemias
Japanese-Brazilians
Diabetes
Cardiometabolic risk
Dislipidemias
Nipo-brasileiros
Diabetes
Risco cardiometabólico
description High prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged >30 years. Hypercholesterolemia was defined as serum cholesterol > 240 mg/dL, hypertriglyceridemia as values > 150 mg/dL and low-HDL-C as values <40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7±196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1- 26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total / HDL-cholesterol ratio was lower in women (4.23 ± 0.68 vs. 4.40 ± 0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health.
publishDate 2008
dc.date.none.fl_str_mv 2008-02-01
2015-06-14T13:38:24Z
2015-06-14T13:38:24Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0004-27302008000100007
Arquivos Brasileiros de Endocrinologia & Metabologia. Sociedade Brasileira de Endocrinologia e Metabologia, v. 52, n. 1, p. 40-46, 2008.
10.1590/S0004-27302008000100007
S0004-27302008000100007.pdf
0004-2730
S0004-27302008000100007
http://repositorio.unifesp.br/handle/11600/4240
url http://dx.doi.org/10.1590/S0004-27302008000100007
http://repositorio.unifesp.br/handle/11600/4240
identifier_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia. Sociedade Brasileira de Endocrinologia e Metabologia, v. 52, n. 1, p. 40-46, 2008.
10.1590/S0004-27302008000100007
S0004-27302008000100007.pdf
0004-2730
S0004-27302008000100007
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Arquivos Brasileiros de Endocrinologia & Metabologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 40-46
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
publisher.none.fl_str_mv Sociedade Brasileira de Endocrinologia e Metabologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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