Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira
Autor(a) principal: | |
---|---|
Data de Publicação: | 2008 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S0004-27302008000100007 http://repositorio.unifesp.br/handle/11600/4240 |
Resumo: | High prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged >30 years. Hypercholesterolemia was defined as serum cholesterol > 240 mg/dL, hypertriglyceridemia as values > 150 mg/dL and low-HDL-C as values <40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7±196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1- 26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total / HDL-cholesterol ratio was lower in women (4.23 ± 0.68 vs. 4.40 ± 0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health. |
id |
UFSP_421d87019784bd8d0930d998e300c188 |
---|---|
oai_identifier_str |
oai:repositorio.unifesp.br/:11600/4240 |
network_acronym_str |
UFSP |
network_name_str |
Repositório Institucional da UNIFESP |
repository_id_str |
3465 |
spelling |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileiraLipid profile disturbances are highly prevalent in Japanese-BraziliansDyslipidemiasJapanese-BraziliansDiabetesCardiometabolic riskDislipidemiasNipo-brasileirosDiabetesRisco cardiometabólicoHigh prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged >30 years. Hypercholesterolemia was defined as serum cholesterol > 240 mg/dL, hypertriglyceridemia as values > 150 mg/dL and low-HDL-C as values <40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7±196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1- 26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total / HDL-cholesterol ratio was lower in women (4.23 ± 0.68 vs. 4.40 ± 0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health.Alta prevalência de diabetes em população nipo-brasileira de Bauru/SP foi previamente relatada. Visando a complementar a avaliação do risco cardiometabólico, este estudo analisou distúrbios no perfil lipídico de 1.330 nipo-brasileiros (46% homens) > 30 anos. Definiu-se hipercolesterolemia por níveis de colesterol total > 240 mg/dL; hipertrigliceridemia por valores > 150 mg/dL e HDL-colesterol baixo por valores < 40 mg/dL e < 50 mg/dL para homens e mulheres, respectivamente. A prevalência desses distúrbios foi comparada pelo qui-quadrado, estratificando-se por sexos e categorias glicêmicas. As médias dos lipídeos e lipoproteínas foram comparadas entre sexos pelo teste t de Student. A prevalência de hipertrigliceridemia foi de 66,0% (IC95%:63,5 - 68,5%), sendo mais comum em homens e aumentando com a piora da categoria glicêmica; a trigliceridemia média foi 235,7 ± 196,3 mg/dL. A prevalência de hipercolesterolemia foi 24,4% (IC95%:22,1 - 26,7%); HDL-C baixo foi observado em 43,0% (IC95%:39,4 - 46,6%] das mulheres e 17,5% (IC95%:14,5 - 20,5%) dos homens, porém a razão colesterol total/HDL-C foi menor em mulheres (4,23 ± 0,68 vs. 4,40 ± 0,73; p < 0,001). Em nipo-brasileiros, a hipertrigliceridemia é a anormalidade lipídica mais comum, em concordância com a elevada prevalência de diabetes. Os homens apresentaram pior perfil lipídico que as mulheres. Sugere-se que hábitos de vida ocidental possam estar deteriorando a saúde desses indivíduos.Universidade Federal de São Paulo (UNIFESP) EPM Departamento de MedicinaUniversidade Federal de São Paulo (UNIFESP) EPM Departamento de Medicina PreventivaUniversidade de São Paulo Faculdade de Saúde Pública Departamento de NutriçãoJapanese-Brazilian Diabetes Study GroupUNIFESP, EPM, Depto. de MedicinaUNIFESP, EPM, Depto. de Medicina PreventivaSciELOFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Sociedade Brasileira de Endocrinologia e MetabologiaUniversidade Federal de São Paulo (UNIFESP)Universidade de São Paulo (USP)Japanese-Brazilian Diabetes Study GroupSiqueira, Antonela F. A. [UNIFESP]Harima, Helena A. [UNIFESP]Osiro, Katsumi [UNIFESP]Hirai, Amélia Toyomi [UNIFESP]Gimeno, Suely Godoy Agostinho [UNIFESP]Ferreira, Sandra Roberta Gouvea [UNIFESP]2015-06-14T13:38:24Z2015-06-14T13:38:24Z2008-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion40-46application/pdfhttp://dx.doi.org/10.1590/S0004-27302008000100007Arquivos Brasileiros de Endocrinologia & Metabologia. Sociedade Brasileira de Endocrinologia e Metabologia, v. 52, n. 1, p. 40-46, 2008.10.1590/S0004-27302008000100007S0004-27302008000100007.pdf0004-2730S0004-27302008000100007http://repositorio.unifesp.br/handle/11600/4240porArquivos Brasileiros de Endocrinologia & Metabologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T09:58:26Zoai:repositorio.unifesp.br/:11600/4240Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T09:58:26Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira Lipid profile disturbances are highly prevalent in Japanese-Brazilians |
title |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira |
spellingShingle |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira Siqueira, Antonela F. A. [UNIFESP] Dyslipidemias Japanese-Brazilians Diabetes Cardiometabolic risk Dislipidemias Nipo-brasileiros Diabetes Risco cardiometabólico |
title_short |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira |
title_full |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira |
title_fullStr |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira |
title_full_unstemmed |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira |
title_sort |
Distúrbios no perfil lipídico são altamente prevalentes em população nipo-brasileira |
author |
Siqueira, Antonela F. A. [UNIFESP] |
author_facet |
Siqueira, Antonela F. A. [UNIFESP] Harima, Helena A. [UNIFESP] Osiro, Katsumi [UNIFESP] Hirai, Amélia Toyomi [UNIFESP] Gimeno, Suely Godoy Agostinho [UNIFESP] Ferreira, Sandra Roberta Gouvea [UNIFESP] |
author_role |
author |
author2 |
Harima, Helena A. [UNIFESP] Osiro, Katsumi [UNIFESP] Hirai, Amélia Toyomi [UNIFESP] Gimeno, Suely Godoy Agostinho [UNIFESP] Ferreira, Sandra Roberta Gouvea [UNIFESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Universidade de São Paulo (USP) Japanese-Brazilian Diabetes Study Group |
dc.contributor.author.fl_str_mv |
Siqueira, Antonela F. A. [UNIFESP] Harima, Helena A. [UNIFESP] Osiro, Katsumi [UNIFESP] Hirai, Amélia Toyomi [UNIFESP] Gimeno, Suely Godoy Agostinho [UNIFESP] Ferreira, Sandra Roberta Gouvea [UNIFESP] |
dc.subject.por.fl_str_mv |
Dyslipidemias Japanese-Brazilians Diabetes Cardiometabolic risk Dislipidemias Nipo-brasileiros Diabetes Risco cardiometabólico |
topic |
Dyslipidemias Japanese-Brazilians Diabetes Cardiometabolic risk Dislipidemias Nipo-brasileiros Diabetes Risco cardiometabólico |
description |
High prevalence of diabetes has been previously reported in Japanese-Brazilians. In an attempt to better estimate the cardiometabolic risk, this study evaluated lipid disorders in 1,330 Japanese-Brazilians (46% men) aged >30 years. Hypercholesterolemia was defined as serum cholesterol > 240 mg/dL, hypertriglyceridemia as values > 150 mg/dL and low-HDL-C as values <40 mg/dL and <50 mg/dl for men and women respectively. The prevalence of dyslipidemias was compared by the chi-square test between gender and glycemic category. Mean and Standard Deviation of lipids and lipoproteins were compared by the Student t-Test between gender. Hypertriglyceridemia was detected in 66.0% [95% CI: 63.5-68.5] of the population, being more common in men and increasing with deterioration of glucose metabolism. Mean level of triglycerides was 235.7±196.3 mg/dL. The prevalence of hypercholesterolemia was 24.4% [95% CI: 22.1- 26.7]. Low HDL-C was observed in 17.5% [95% CI: 14.5-20.5] of men and 43.0% [95% CI: 39.4- 46.6] of women but total / HDL-cholesterol ratio was lower in women (4.23 ± 0.68 vs. 4.40 ± 0.73, p<0.001). In Japanese-Brazilians, hypertriglyceridemia is the commonest dyslipidemia, in agreement with the high prevalence of diabetes. Men showed a worse lipid profile than women; it was suggested that the Western diet and living habits could be deteriorating their health. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-02-01 2015-06-14T13:38:24Z 2015-06-14T13:38:24Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0004-27302008000100007 Arquivos Brasileiros de Endocrinologia & Metabologia. Sociedade Brasileira de Endocrinologia e Metabologia, v. 52, n. 1, p. 40-46, 2008. 10.1590/S0004-27302008000100007 S0004-27302008000100007.pdf 0004-2730 S0004-27302008000100007 http://repositorio.unifesp.br/handle/11600/4240 |
url |
http://dx.doi.org/10.1590/S0004-27302008000100007 http://repositorio.unifesp.br/handle/11600/4240 |
identifier_str_mv |
Arquivos Brasileiros de Endocrinologia & Metabologia. Sociedade Brasileira de Endocrinologia e Metabologia, v. 52, n. 1, p. 40-46, 2008. 10.1590/S0004-27302008000100007 S0004-27302008000100007.pdf 0004-2730 S0004-27302008000100007 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Arquivos Brasileiros de Endocrinologia & Metabologia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
40-46 application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Endocrinologia e Metabologia |
publisher.none.fl_str_mv |
Sociedade Brasileira de Endocrinologia e Metabologia |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268294574637056 |