High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/51259 http://dx.doi.org/10.1016/j.bjid.2017.05.004 |
Resumo: | Brazil is a non-endemic country for hepatitis E virus (HEV) infection with seroprevalence from 1% to 4% in blood donors and the general population. However, data on seroprevalence of HEV in the country are still limited. This study evaluated the prevalence of past or present HEV infection in a group of blood donors representative of the general population of the city of Sao Paulo, Southeastern Brazil. Serum samples from 500 blood donors were tested from July to September 2014 by serological and molecular methods. Anti-HEV IgG antibodies were detected in 49 (9.8%) subjects and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Among the anti-HEV IgG positive subjects, only 1 had anti-HEV IgM while none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG than previously reported in the region. (C) 2017 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. |
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Passos-Castilho, Ana Maria [UNIFESP]Reinaldo, Monica Renata [UNIFESP]de Sena, Anne [UNIFESP]Granato, Celso F. H. [UNIFESP]2019-08-19T11:48:28Z2019-08-19T11:48:28Z2017Brazilian Journal Of Infectious Diseases. Rio De Janeiro, v. 21, n. 5, p. 535-539, 2017.1413-8670http://repositorio.unifesp.br/handle/11600/51259http://dx.doi.org/10.1016/j.bjid.2017.05.004WOS000414276300008.pdfS1413-8670201700050053510.1016/j.bjid.2017.05.004WOS:000414276300008Brazil is a non-endemic country for hepatitis E virus (HEV) infection with seroprevalence from 1% to 4% in blood donors and the general population. However, data on seroprevalence of HEV in the country are still limited. This study evaluated the prevalence of past or present HEV infection in a group of blood donors representative of the general population of the city of Sao Paulo, Southeastern Brazil. Serum samples from 500 blood donors were tested from July to September 2014 by serological and molecular methods. Anti-HEV IgG antibodies were detected in 49 (9.8%) subjects and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Among the anti-HEV IgG positive subjects, only 1 had anti-HEV IgM while none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG than previously reported in the region. (C) 2017 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Univ Fed São Paulo, Div Infect Dis, São Paulo, SP, BrazilFleury SA Grp, São Paulo, SP, BrazilUniv Fed São Paulo, Div Infect Dis, São Paulo, SP, BrazilFAPESP: 2012/22925-3FAPESP: 2013/03701-0Web of Science535-539engElsevier BrazilHepatitis E virusBlood donorsSeroprevalenceBrazilHigh prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general populationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000414276300008.pdfapplication/pdf780829${dspace.ui.url}/bitstream/11600/51259/1/WOS000414276300008.pdf5b5b4e3c7e5b5f473fc1f35d5622a604MD51open accessTEXTWOS000414276300008.pdf.txtWOS000414276300008.pdf.txtExtracted texttext/plain21432${dspace.ui.url}/bitstream/11600/51259/2/WOS000414276300008.pdf.txt89d21170bd1936998d6318413f4841ddMD52open accessTHUMBNAILWOS000414276300008.pdf.jpgWOS000414276300008.pdf.jpgIM Thumbnailimage/jpeg7081${dspace.ui.url}/bitstream/11600/51259/4/WOS000414276300008.pdf.jpg09e7d115da2e52d36897c2c3950bcdc3MD54open access11600/512592022-08-01 18:49:02.276open accessoai:repositorio.unifesp.br:11600/51259Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652022-08-01T21:49:02Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population |
title |
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population |
spellingShingle |
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population Passos-Castilho, Ana Maria [UNIFESP] Hepatitis E virus Blood donors Seroprevalence Brazil |
title_short |
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population |
title_full |
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population |
title_fullStr |
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population |
title_full_unstemmed |
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population |
title_sort |
High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population |
author |
Passos-Castilho, Ana Maria [UNIFESP] |
author_facet |
Passos-Castilho, Ana Maria [UNIFESP] Reinaldo, Monica Renata [UNIFESP] de Sena, Anne [UNIFESP] Granato, Celso F. H. [UNIFESP] |
author_role |
author |
author2 |
Reinaldo, Monica Renata [UNIFESP] de Sena, Anne [UNIFESP] Granato, Celso F. H. [UNIFESP] |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Passos-Castilho, Ana Maria [UNIFESP] Reinaldo, Monica Renata [UNIFESP] de Sena, Anne [UNIFESP] Granato, Celso F. H. [UNIFESP] |
dc.subject.eng.fl_str_mv |
Hepatitis E virus Blood donors Seroprevalence Brazil |
topic |
Hepatitis E virus Blood donors Seroprevalence Brazil |
description |
Brazil is a non-endemic country for hepatitis E virus (HEV) infection with seroprevalence from 1% to 4% in blood donors and the general population. However, data on seroprevalence of HEV in the country are still limited. This study evaluated the prevalence of past or present HEV infection in a group of blood donors representative of the general population of the city of Sao Paulo, Southeastern Brazil. Serum samples from 500 blood donors were tested from July to September 2014 by serological and molecular methods. Anti-HEV IgG antibodies were detected in 49 (9.8%) subjects and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Among the anti-HEV IgG positive subjects, only 1 had anti-HEV IgM while none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG than previously reported in the region. (C) 2017 Sociedade Brasileira de Infectologia. Published by Elsevier Editora Ltda. |
publishDate |
2017 |
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2017 |
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2019-08-19T11:48:28Z |
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2019-08-19T11:48:28Z |
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info:eu-repo/semantics/publishedVersion |
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Brazilian Journal Of Infectious Diseases. Rio De Janeiro, v. 21, n. 5, p. 535-539, 2017. |
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http://repositorio.unifesp.br/handle/11600/51259 http://dx.doi.org/10.1016/j.bjid.2017.05.004 |
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1413-8670 |
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WOS000414276300008.pdf |
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S1413-86702017000500535 |
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10.1016/j.bjid.2017.05.004 |
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WOS:000414276300008 |
identifier_str_mv |
Brazilian Journal Of Infectious Diseases. Rio De Janeiro, v. 21, n. 5, p. 535-539, 2017. 1413-8670 WOS000414276300008.pdf S1413-86702017000500535 10.1016/j.bjid.2017.05.004 WOS:000414276300008 |
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http://repositorio.unifesp.br/handle/11600/51259 http://dx.doi.org/10.1016/j.bjid.2017.05.004 |
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Elsevier Brazil |
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Elsevier Brazil |
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