Esophageal ulcer and alendronate

Detalhes bibliográficos
Autor(a) principal: Ferrari, Angelo Paulo [UNIFESP]
Data de Publicação: 1998
Outros Autores: Domingues, Sérgio Hernani Stuhr [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S1516-31801998000600010
http://repositorio.unifesp.br/handle/11600/687
Resumo: OBJECTIVE: To describe a case of esophageal ulcer associated with the use of alendronate.CASE REPORT: This is the fifth case ever described in the literature according to our bibliographic review. In our patient, the association between the drug and the esophageal lesions was masked by the presence of a hiatal hernia, potentially a cause of the esophageal lesion. The persistence of the lesions despite high doses of anti-reflux therapy called attention to the possibility of the relationship. The esophageal lesion healed soon after suspension of alendronate.DISCUSSION: The authors present a review of the literature and point to the need for diagnostic investigation, to suspend such a drug from patients who experience dyspeptic symptoms while using it.
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spelling Esophageal ulcer and alendronateEndoscopyAlendronateEsophageal ulcerOBJECTIVE: To describe a case of esophageal ulcer associated with the use of alendronate.CASE REPORT: This is the fifth case ever described in the literature according to our bibliographic review. In our patient, the association between the drug and the esophageal lesions was masked by the presence of a hiatal hernia, potentially a cause of the esophageal lesion. The persistence of the lesions despite high doses of anti-reflux therapy called attention to the possibility of the relationship. The esophageal lesion healed soon after suspension of alendronate.DISCUSSION: The authors present a review of the literature and point to the need for diagnostic investigation, to suspend such a drug from patients who experience dyspeptic symptoms while using it.OBJETIVO: Descrever um caso de úlcera esofágica associada ao uso de alendronato. RELATO DE CASO: Este, segundo nossa pesquisa bibliográfica, é o quinto caso descrito na literatura. Em nossa paciente, a associação entre a droga e a lesão esofágica foi mascarada pela presença de hérnia de hiato, potencialmente causadora de lesão de esôfago. A persistência da lesão apesar de doses elevadas de medicação anti-refluxo gastro-esofágica alertou para a possível associação. A lesão esofágica cicatrizou logo após a retirada do alendronato. DISCUSSÃO: Os autores fazem uma revisão da literatura e alertam para a necessidade de investigação diagnóstica e retirada da droga, em pacientes em uso de alendronato e que desenvolvem queixas dispépticas.Universidade Federal de São Paulo (UNIFESP)UNIFESPSciELOAssociação Paulista de Medicina - APMUniversidade Federal de São Paulo (UNIFESP)Ferrari, Angelo Paulo [UNIFESP]Domingues, Sérgio Hernani Stuhr [UNIFESP]2015-06-14T13:24:47Z2015-06-14T13:24:47Z1998-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1882-1884application/pdfhttp://dx.doi.org/10.1590/S1516-31801998000600010São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 116, n. 6, p. 1882-1884, 1998.10.1590/S1516-31801998000600010S1516-31801998000600010.pdf1516-3180S1516-31801998000600010http://repositorio.unifesp.br/handle/11600/687engSão Paulo Medical Journalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T06:19:55Zoai:repositorio.unifesp.br/:11600/687Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T06:19:55Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Esophageal ulcer and alendronate
title Esophageal ulcer and alendronate
spellingShingle Esophageal ulcer and alendronate
Ferrari, Angelo Paulo [UNIFESP]
Endoscopy
Alendronate
Esophageal ulcer
title_short Esophageal ulcer and alendronate
title_full Esophageal ulcer and alendronate
title_fullStr Esophageal ulcer and alendronate
title_full_unstemmed Esophageal ulcer and alendronate
title_sort Esophageal ulcer and alendronate
author Ferrari, Angelo Paulo [UNIFESP]
author_facet Ferrari, Angelo Paulo [UNIFESP]
Domingues, Sérgio Hernani Stuhr [UNIFESP]
author_role author
author2 Domingues, Sérgio Hernani Stuhr [UNIFESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Ferrari, Angelo Paulo [UNIFESP]
Domingues, Sérgio Hernani Stuhr [UNIFESP]
dc.subject.por.fl_str_mv Endoscopy
Alendronate
Esophageal ulcer
topic Endoscopy
Alendronate
Esophageal ulcer
description OBJECTIVE: To describe a case of esophageal ulcer associated with the use of alendronate.CASE REPORT: This is the fifth case ever described in the literature according to our bibliographic review. In our patient, the association between the drug and the esophageal lesions was masked by the presence of a hiatal hernia, potentially a cause of the esophageal lesion. The persistence of the lesions despite high doses of anti-reflux therapy called attention to the possibility of the relationship. The esophageal lesion healed soon after suspension of alendronate.DISCUSSION: The authors present a review of the literature and point to the need for diagnostic investigation, to suspend such a drug from patients who experience dyspeptic symptoms while using it.
publishDate 1998
dc.date.none.fl_str_mv 1998-11-01
2015-06-14T13:24:47Z
2015-06-14T13:24:47Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1516-31801998000600010
São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 116, n. 6, p. 1882-1884, 1998.
10.1590/S1516-31801998000600010
S1516-31801998000600010.pdf
1516-3180
S1516-31801998000600010
http://repositorio.unifesp.br/handle/11600/687
url http://dx.doi.org/10.1590/S1516-31801998000600010
http://repositorio.unifesp.br/handle/11600/687
identifier_str_mv São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 116, n. 6, p. 1882-1884, 1998.
10.1590/S1516-31801998000600010
S1516-31801998000600010.pdf
1516-3180
S1516-31801998000600010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv São Paulo Medical Journal
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1882-1884
application/pdf
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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