Esophageal ulcer and alendronate
Autor(a) principal: | |
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Data de Publicação: | 1998 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S1516-31801998000600010 http://repositorio.unifesp.br/handle/11600/687 |
Resumo: | OBJECTIVE: To describe a case of esophageal ulcer associated with the use of alendronate.CASE REPORT: This is the fifth case ever described in the literature according to our bibliographic review. In our patient, the association between the drug and the esophageal lesions was masked by the presence of a hiatal hernia, potentially a cause of the esophageal lesion. The persistence of the lesions despite high doses of anti-reflux therapy called attention to the possibility of the relationship. The esophageal lesion healed soon after suspension of alendronate.DISCUSSION: The authors present a review of the literature and point to the need for diagnostic investigation, to suspend such a drug from patients who experience dyspeptic symptoms while using it. |
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Esophageal ulcer and alendronateEndoscopyAlendronateEsophageal ulcerOBJECTIVE: To describe a case of esophageal ulcer associated with the use of alendronate.CASE REPORT: This is the fifth case ever described in the literature according to our bibliographic review. In our patient, the association between the drug and the esophageal lesions was masked by the presence of a hiatal hernia, potentially a cause of the esophageal lesion. The persistence of the lesions despite high doses of anti-reflux therapy called attention to the possibility of the relationship. The esophageal lesion healed soon after suspension of alendronate.DISCUSSION: The authors present a review of the literature and point to the need for diagnostic investigation, to suspend such a drug from patients who experience dyspeptic symptoms while using it.OBJETIVO: Descrever um caso de úlcera esofágica associada ao uso de alendronato. RELATO DE CASO: Este, segundo nossa pesquisa bibliográfica, é o quinto caso descrito na literatura. Em nossa paciente, a associação entre a droga e a lesão esofágica foi mascarada pela presença de hérnia de hiato, potencialmente causadora de lesão de esôfago. A persistência da lesão apesar de doses elevadas de medicação anti-refluxo gastro-esofágica alertou para a possível associação. A lesão esofágica cicatrizou logo após a retirada do alendronato. DISCUSSÃO: Os autores fazem uma revisão da literatura e alertam para a necessidade de investigação diagnóstica e retirada da droga, em pacientes em uso de alendronato e que desenvolvem queixas dispépticas.Universidade Federal de São Paulo (UNIFESP)UNIFESPSciELOAssociação Paulista de Medicina - APMUniversidade Federal de São Paulo (UNIFESP)Ferrari, Angelo Paulo [UNIFESP]Domingues, Sérgio Hernani Stuhr [UNIFESP]2015-06-14T13:24:47Z2015-06-14T13:24:47Z1998-11-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1882-1884application/pdfhttp://dx.doi.org/10.1590/S1516-31801998000600010São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 116, n. 6, p. 1882-1884, 1998.10.1590/S1516-31801998000600010S1516-31801998000600010.pdf1516-3180S1516-31801998000600010http://repositorio.unifesp.br/handle/11600/687engSão Paulo Medical Journalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T06:19:55Zoai:repositorio.unifesp.br/:11600/687Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T06:19:55Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Esophageal ulcer and alendronate |
title |
Esophageal ulcer and alendronate |
spellingShingle |
Esophageal ulcer and alendronate Ferrari, Angelo Paulo [UNIFESP] Endoscopy Alendronate Esophageal ulcer |
title_short |
Esophageal ulcer and alendronate |
title_full |
Esophageal ulcer and alendronate |
title_fullStr |
Esophageal ulcer and alendronate |
title_full_unstemmed |
Esophageal ulcer and alendronate |
title_sort |
Esophageal ulcer and alendronate |
author |
Ferrari, Angelo Paulo [UNIFESP] |
author_facet |
Ferrari, Angelo Paulo [UNIFESP] Domingues, Sérgio Hernani Stuhr [UNIFESP] |
author_role |
author |
author2 |
Domingues, Sérgio Hernani Stuhr [UNIFESP] |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Ferrari, Angelo Paulo [UNIFESP] Domingues, Sérgio Hernani Stuhr [UNIFESP] |
dc.subject.por.fl_str_mv |
Endoscopy Alendronate Esophageal ulcer |
topic |
Endoscopy Alendronate Esophageal ulcer |
description |
OBJECTIVE: To describe a case of esophageal ulcer associated with the use of alendronate.CASE REPORT: This is the fifth case ever described in the literature according to our bibliographic review. In our patient, the association between the drug and the esophageal lesions was masked by the presence of a hiatal hernia, potentially a cause of the esophageal lesion. The persistence of the lesions despite high doses of anti-reflux therapy called attention to the possibility of the relationship. The esophageal lesion healed soon after suspension of alendronate.DISCUSSION: The authors present a review of the literature and point to the need for diagnostic investigation, to suspend such a drug from patients who experience dyspeptic symptoms while using it. |
publishDate |
1998 |
dc.date.none.fl_str_mv |
1998-11-01 2015-06-14T13:24:47Z 2015-06-14T13:24:47Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1516-31801998000600010 São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 116, n. 6, p. 1882-1884, 1998. 10.1590/S1516-31801998000600010 S1516-31801998000600010.pdf 1516-3180 S1516-31801998000600010 http://repositorio.unifesp.br/handle/11600/687 |
url |
http://dx.doi.org/10.1590/S1516-31801998000600010 http://repositorio.unifesp.br/handle/11600/687 |
identifier_str_mv |
São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 116, n. 6, p. 1882-1884, 1998. 10.1590/S1516-31801998000600010 S1516-31801998000600010.pdf 1516-3180 S1516-31801998000600010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
São Paulo Medical Journal |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1882-1884 application/pdf |
dc.publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
publisher.none.fl_str_mv |
Associação Paulista de Medicina - APM |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268351308890112 |