Anaplastic Ganglioglioma of the Pineal Region - A Case Report
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNIFESP |
| Texto Completo: | http://dx.doi.org/10.1055/s-0035-1564583 http://repositorio.unifesp.br/handle/11600/51033 |
Resumo: | Introduction Gangliogliomas are tumors commonly found in the temporal lobe and related to seizures |
| id |
UFSP_4711b3cffb385f0cf480d07d9a16c23f |
|---|---|
| oai_identifier_str |
oai:repositorio.unifesp.br/:11600/51033 |
| network_acronym_str |
UFSP |
| network_name_str |
Repositório Institucional da UNIFESP |
| repository_id_str |
3465 |
| spelling |
Anaplastic Ganglioglioma of the Pineal Region - A Case Reportpineal glandbrain tumormalignant gangliogliomaIntroduction Gangliogliomas are tumors commonly found in the temporal lobe and related to seizurestheir appearance in the pineal region is rarely described. This report characterizes the first case of anaplastic ganglioglioma of the pineal region. Case Report The authors describe the case of a 32-year-old woman that developed progressive headache. AnMRI investigation revealed a pineal tumor. The patient tested negative for biomarkers and underwent surgery through supracerebellar infratentorial approach and achieved gross total resection of the tumor in a challenging location. Pathological analysis revealed a biphasic neoplasm with the following two distinct phenotypes in separate fields: an immature neuronal component with several atypical mitoses and a mature astrocytic component with bipolar cells, microcysts, and eosinophilic bodies. The Ki67/MIB1 proliferation index was 20-30% in localized hotspots. Based on the pathological findings, the tumor was defined as an anaplastic ganglioglioma World Health Organization (WHO) grade III. Discussion/Conclusion Gangliogliomas are classified as glioneural neoplasms based on the histologic findings described as a mixture of neoplastic astrocytes and neurons. Moreover, these tumors represent 0.4-1.3% of tumors of the central nervous system. Authors describe de novo anaplastic ganglioglioma as 1% of the largest series. Gross total resection and adjuvant treatment may play important role in patients' prognostic. In this case, due to the malignant anaplastic component of her tumor, the patient received treatment with temozolamide and radiotherapy after gross total resection of the lesion.Univ Fed Sao Paulo, Escola Paulista Med, Dept Neurosurg, Sao Paulo, SP, BrazilInst Ciencias Neurol, Sao Paulo, SP, BrazilFac Ciencias Med Santa Casa Sao Paulo, Dept Neuropathol, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Escola Paulista Med, Dept Neurosurg, Sao Paulo, SP, BrazilWeb of ScienceGeorg Thieme Verlag Kg2019-07-22T15:46:42Z2019-07-22T15:46:42Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion253-256http://dx.doi.org/10.1055/s-0035-1564583Brazilian Neurosurgery-Arquivos Brasileiros De Neurocirurgia. Stuttgart, v. 35, n. 3, p. 253-256, 2016.10.1055/s-0035-1564583WOS000392470000014.pdf0103-5355http://repositorio.unifesp.br/handle/11600/51033WOS:000392470000014enginfo:eu-repo/semantics/openAccessSilva da Costa, Marcos Devanir [UNIFESP]Centeno, Ricardo Silva [UNIFESP]Neto, Mateus ReghinDoria Netto, Hugo LeonardoCampos Filho, Jose MariaPaz, Daniel de Araujo [UNIFESP]Rodrigues, Thiago Pereira [UNIFESP]Telles, Bruno AugustoPenteado Lancellotti, Carmen LuciaCavalheiro, SergioChaddad-Neto, Feres [UNIFESP]reponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2022-02-08T12:11:15Zoai:repositorio.unifesp.br/:11600/51033Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652022-02-08T12:11:15Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
| dc.title.none.fl_str_mv |
Anaplastic Ganglioglioma of the Pineal Region - A Case Report |
| title |
Anaplastic Ganglioglioma of the Pineal Region - A Case Report |
| spellingShingle |
Anaplastic Ganglioglioma of the Pineal Region - A Case Report Silva da Costa, Marcos Devanir [UNIFESP] pineal gland brain tumor malignant ganglioglioma |
| title_short |
Anaplastic Ganglioglioma of the Pineal Region - A Case Report |
| title_full |
Anaplastic Ganglioglioma of the Pineal Region - A Case Report |
| title_fullStr |
Anaplastic Ganglioglioma of the Pineal Region - A Case Report |
| title_full_unstemmed |
Anaplastic Ganglioglioma of the Pineal Region - A Case Report |
| title_sort |
Anaplastic Ganglioglioma of the Pineal Region - A Case Report |
| author |
Silva da Costa, Marcos Devanir [UNIFESP] |
| author_facet |
Silva da Costa, Marcos Devanir [UNIFESP] Centeno, Ricardo Silva [UNIFESP] Neto, Mateus Reghin Doria Netto, Hugo Leonardo Campos Filho, Jose Maria Paz, Daniel de Araujo [UNIFESP] Rodrigues, Thiago Pereira [UNIFESP] Telles, Bruno Augusto Penteado Lancellotti, Carmen Lucia Cavalheiro, Sergio Chaddad-Neto, Feres [UNIFESP] |
| author_role |
author |
| author2 |
Centeno, Ricardo Silva [UNIFESP] Neto, Mateus Reghin Doria Netto, Hugo Leonardo Campos Filho, Jose Maria Paz, Daniel de Araujo [UNIFESP] Rodrigues, Thiago Pereira [UNIFESP] Telles, Bruno Augusto Penteado Lancellotti, Carmen Lucia Cavalheiro, Sergio Chaddad-Neto, Feres [UNIFESP] |
| author2_role |
author author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Silva da Costa, Marcos Devanir [UNIFESP] Centeno, Ricardo Silva [UNIFESP] Neto, Mateus Reghin Doria Netto, Hugo Leonardo Campos Filho, Jose Maria Paz, Daniel de Araujo [UNIFESP] Rodrigues, Thiago Pereira [UNIFESP] Telles, Bruno Augusto Penteado Lancellotti, Carmen Lucia Cavalheiro, Sergio Chaddad-Neto, Feres [UNIFESP] |
| dc.subject.por.fl_str_mv |
pineal gland brain tumor malignant ganglioglioma |
| topic |
pineal gland brain tumor malignant ganglioglioma |
| description |
Introduction Gangliogliomas are tumors commonly found in the temporal lobe and related to seizures |
| publishDate |
2016 |
| dc.date.none.fl_str_mv |
2016 2019-07-22T15:46:42Z 2019-07-22T15:46:42Z |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1055/s-0035-1564583 Brazilian Neurosurgery-Arquivos Brasileiros De Neurocirurgia. Stuttgart, v. 35, n. 3, p. 253-256, 2016. 10.1055/s-0035-1564583 WOS000392470000014.pdf 0103-5355 http://repositorio.unifesp.br/handle/11600/51033 WOS:000392470000014 |
| url |
http://dx.doi.org/10.1055/s-0035-1564583 http://repositorio.unifesp.br/handle/11600/51033 |
| identifier_str_mv |
Brazilian Neurosurgery-Arquivos Brasileiros De Neurocirurgia. Stuttgart, v. 35, n. 3, p. 253-256, 2016. 10.1055/s-0035-1564583 WOS000392470000014.pdf 0103-5355 WOS:000392470000014 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
253-256 |
| dc.publisher.none.fl_str_mv |
Georg Thieme Verlag Kg |
| publisher.none.fl_str_mv |
Georg Thieme Verlag Kg |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
| instname_str |
Universidade Federal de São Paulo (UNIFESP) |
| instacron_str |
UNIFESP |
| institution |
UNIFESP |
| reponame_str |
Repositório Institucional da UNIFESP |
| collection |
Repositório Institucional da UNIFESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
| repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
| _version_ |
1814268356078862336 |