Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination

Detalhes bibliográficos
Autor(a) principal: Lafer, Manuel Mindlin [UNIFESP]
Data de Publicação: 2005
Outros Autores: De Moraes-Pinto, Maria Isabel [UNIFESP], Weckx, Lily Yin [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0036-46652005000300004
http://repositorio.unifesp.br/handle/11600/2552
Resumo: The purpose of the study was to estimate the prevalence of IgG antibodies against varicella zoster virus (VZV) in the two most populated indigenous ethnic groups from Xingu Indigenous National Park, in Brazil, prior to the introduction of vaccination against the disease, and to determine the positive and the negative predictive values of a history of varicella infection. In 2001, 589 inhabitants of two Kuikuro villages and three Kaiabi villages were evaluated and provided information concerning previous varicella infection. An indirect immunosorbent assay (ELISA) to detect IgG anti-VZV antibodies was performed in 224 blood samples - volunteer selection had no interference of anamnesis. IgG prevalence was 80.8% (95% Confidence Interval: 76% - 86%). The seroepidemiology of varicella in Xingu National Park prior to varicella vaccine introduction was comparable to the Brazilian national seroprevalence described in the literature, and so were the positive (98%) and the negative predictive value (41%) of the referred history.
id UFSP_493cc95f3c5ea8c2123b2a4c30fd66ec
oai_identifier_str oai:repositorio.unifesp.br/:11600/2552
network_acronym_str UFSP
network_name_str Repositório Institucional da UNIFESP
repository_id_str 3465
spelling Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccinationPrevalência de anticorpos IgG contra o vírus varicela zoster nas aldeias indígenas Kuikuro e Kaiabi do Parque Nacional do Xingu, Brasil, antes da vacinação contra varicelaVaricella ZosterAntibodiesBrazilian native IndiansThe purpose of the study was to estimate the prevalence of IgG antibodies against varicella zoster virus (VZV) in the two most populated indigenous ethnic groups from Xingu Indigenous National Park, in Brazil, prior to the introduction of vaccination against the disease, and to determine the positive and the negative predictive values of a history of varicella infection. In 2001, 589 inhabitants of two Kuikuro villages and three Kaiabi villages were evaluated and provided information concerning previous varicella infection. An indirect immunosorbent assay (ELISA) to detect IgG anti-VZV antibodies was performed in 224 blood samples - volunteer selection had no interference of anamnesis. IgG prevalence was 80.8% (95% Confidence Interval: 76% - 86%). The seroepidemiology of varicella in Xingu National Park prior to varicella vaccine introduction was comparable to the Brazilian national seroprevalence described in the literature, and so were the positive (98%) and the negative predictive value (41%) of the referred history.O objetivo do estudo foi aferir a prevalência de anticorpos IgG contra o Vírus Varicela-Zoster (VVZ) nos dois grupos étnicos indígenas mais povoados do Parque Nacional Indígena do Xingu, Brasil, antes da introdução da vacinação contra a doença, e determinar os valores preditivos positivo e negativo da história de infecção de varicela. Em 2001, 589 habitantes de duas aldeias Kuikuro e três aldeias Kaiabi foram avaliados e forneceram dados referentes à infecção prévia por varicela. Um ensaio imunoenzimático indireto (ELISA) foi realizado em 224 amostras de sangue para detectar anticorpos IgG anti-VVZ - a seleção de voluntários não teve interferência da anamnese. A prevalência de IgG foi de 80,8% (Intervalo de Confiança de 95%: 76% - 86%). A soroepidemiologia de varicela no Parque Nacional do Xingu antes da introdução da vacina foi comparável à soroprevalência nacional descrita na literatura, assim como os valores preditivos positivo (98%) e negativo (41%) da história referida.Federal University of São Paulo Division of Pediatric Infectious DiseasesUNIFESP, Division of Pediatric Infectious DiseasesSciELOInstituto de Medicina TropicalUniversidade Federal de São Paulo (UNIFESP)Lafer, Manuel Mindlin [UNIFESP]De Moraes-Pinto, Maria Isabel [UNIFESP]Weckx, Lily Yin [UNIFESP]2015-06-14T13:31:37Z2015-06-14T13:31:37Z2005-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion139-142application/pdfhttp://dx.doi.org/10.1590/S0036-46652005000300004Revista do Instituto de Medicina Tropical de São Paulo. Instituto de Medicina Tropical, v. 47, n. 3, p. 139-142, 2005.10.1590/S0036-46652005000300004S0036-46652005000300004.pdf0036-4665S0036-46652005000300004http://repositorio.unifesp.br/handle/11600/2552engRevista do Instituto de Medicina Tropical de São Pauloinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T14:35:34Zoai:repositorio.unifesp.br/:11600/2552Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-29T14:35:34Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination
Prevalência de anticorpos IgG contra o vírus varicela zoster nas aldeias indígenas Kuikuro e Kaiabi do Parque Nacional do Xingu, Brasil, antes da vacinação contra varicela
title Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination
spellingShingle Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination
Lafer, Manuel Mindlin [UNIFESP]
Varicella Zoster
Antibodies
Brazilian native Indians
title_short Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination
title_full Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination
title_fullStr Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination
title_full_unstemmed Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination
title_sort Prevalence of IgG varicella zoster virus antibodies in the Kuikuro and Kaiabi indigenous communities in Xingu National Park, Brazil, before varicella vaccination
author Lafer, Manuel Mindlin [UNIFESP]
author_facet Lafer, Manuel Mindlin [UNIFESP]
De Moraes-Pinto, Maria Isabel [UNIFESP]
Weckx, Lily Yin [UNIFESP]
author_role author
author2 De Moraes-Pinto, Maria Isabel [UNIFESP]
Weckx, Lily Yin [UNIFESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Lafer, Manuel Mindlin [UNIFESP]
De Moraes-Pinto, Maria Isabel [UNIFESP]
Weckx, Lily Yin [UNIFESP]
dc.subject.por.fl_str_mv Varicella Zoster
Antibodies
Brazilian native Indians
topic Varicella Zoster
Antibodies
Brazilian native Indians
description The purpose of the study was to estimate the prevalence of IgG antibodies against varicella zoster virus (VZV) in the two most populated indigenous ethnic groups from Xingu Indigenous National Park, in Brazil, prior to the introduction of vaccination against the disease, and to determine the positive and the negative predictive values of a history of varicella infection. In 2001, 589 inhabitants of two Kuikuro villages and three Kaiabi villages were evaluated and provided information concerning previous varicella infection. An indirect immunosorbent assay (ELISA) to detect IgG anti-VZV antibodies was performed in 224 blood samples - volunteer selection had no interference of anamnesis. IgG prevalence was 80.8% (95% Confidence Interval: 76% - 86%). The seroepidemiology of varicella in Xingu National Park prior to varicella vaccine introduction was comparable to the Brazilian national seroprevalence described in the literature, and so were the positive (98%) and the negative predictive value (41%) of the referred history.
publishDate 2005
dc.date.none.fl_str_mv 2005-06-01
2015-06-14T13:31:37Z
2015-06-14T13:31:37Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0036-46652005000300004
Revista do Instituto de Medicina Tropical de São Paulo. Instituto de Medicina Tropical, v. 47, n. 3, p. 139-142, 2005.
10.1590/S0036-46652005000300004
S0036-46652005000300004.pdf
0036-4665
S0036-46652005000300004
http://repositorio.unifesp.br/handle/11600/2552
url http://dx.doi.org/10.1590/S0036-46652005000300004
http://repositorio.unifesp.br/handle/11600/2552
identifier_str_mv Revista do Instituto de Medicina Tropical de São Paulo. Instituto de Medicina Tropical, v. 47, n. 3, p. 139-142, 2005.
10.1590/S0036-46652005000300004
S0036-46652005000300004.pdf
0036-4665
S0036-46652005000300004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista do Instituto de Medicina Tropical de São Paulo
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 139-142
application/pdf
dc.publisher.none.fl_str_mv Instituto de Medicina Tropical
publisher.none.fl_str_mv Instituto de Medicina Tropical
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268341996486656