Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes
Autor(a) principal: | |
---|---|
Data de Publicação: | 2004 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S0021-75572004000500013 http://repositorio.unifesp.br/handle/11600/2173 |
Resumo: | OBJECTIVE: To evaluate clinical and histological features of duodenal ulcer in children and adolescents. METHODS: Forty-three children with duodenal ulcer were prospectively and consecutively evaluated in a 6-year period (7.2 patients per year). Evaluation included clinical questionnaire focused on dyspeptic symptoms, physical examination, and digestive endoscopy with gastric biopsies for histological examination and Helicobacter pylori detection. RESULTS: Diagnostic age ranged from 4 years and 8 months to 17 years and 4 months (mean age: 12 years and 4 months). Abdominal pain was the main symptom (39/43, 90.7%), which was epigastric in 31/39, periumbilical in 7/39, and nocturnal in 27/39. Other symptoms were loss of appetite (32/43, 74.4%), vomiting (30/43, 69.8%), postprandial fullness (23/43, 53.5%), weight loss (22/43, 51.2%), and abdominal tenderness (19/43, 44.2%). Upper gastrointestinal bleeding occurred in 19/43 (44.2%), whereas anemia occurred in (21/43, 48.8%). Helicobacter pylori infection was detected in 41/43 (95.3%). All infected patients presented acute chronic gastritis in antrum, with lymphomononuclear infiltrate predominance in 92% of them. Eradication of the bacterium occurred in 68.3%. Ulcer healing occurred in all eradicated patients and in 89% of non-eradicated patients. CONCLUSION: Duodenal ulcer was associated with chronic gastritis due to Helicobacter pylori in the majority of patients. Many complications occurred, especially upper digestive bleeding. |
id |
UFSP_4a680c700643c36c45f598b46c4e45c8 |
---|---|
oai_identifier_str |
oai:repositorio.unifesp.br/:11600/2173 |
network_acronym_str |
UFSP |
network_name_str |
Repositório Institucional da UNIFESP |
repository_id_str |
3465 |
spelling |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentesClinical and histological features of duodenal ulcer in children and adolescentsPeptic ulcerdyspepsiaHelicobacter pyloriChildrenÚlcera pépticadispepsiagastriteHelicobacter pyloriOBJECTIVE: To evaluate clinical and histological features of duodenal ulcer in children and adolescents. METHODS: Forty-three children with duodenal ulcer were prospectively and consecutively evaluated in a 6-year period (7.2 patients per year). Evaluation included clinical questionnaire focused on dyspeptic symptoms, physical examination, and digestive endoscopy with gastric biopsies for histological examination and Helicobacter pylori detection. RESULTS: Diagnostic age ranged from 4 years and 8 months to 17 years and 4 months (mean age: 12 years and 4 months). Abdominal pain was the main symptom (39/43, 90.7%), which was epigastric in 31/39, periumbilical in 7/39, and nocturnal in 27/39. Other symptoms were loss of appetite (32/43, 74.4%), vomiting (30/43, 69.8%), postprandial fullness (23/43, 53.5%), weight loss (22/43, 51.2%), and abdominal tenderness (19/43, 44.2%). Upper gastrointestinal bleeding occurred in 19/43 (44.2%), whereas anemia occurred in (21/43, 48.8%). Helicobacter pylori infection was detected in 41/43 (95.3%). All infected patients presented acute chronic gastritis in antrum, with lymphomononuclear infiltrate predominance in 92% of them. Eradication of the bacterium occurred in 68.3%. Ulcer healing occurred in all eradicated patients and in 89% of non-eradicated patients. CONCLUSION: Duodenal ulcer was associated with chronic gastritis due to Helicobacter pylori in the majority of patients. Many complications occurred, especially upper digestive bleeding.OBJETIVO: Avaliar as características clínicas e histológicas de crianças e adolescentes com úlcera duodenal. MÉTODOS: Foram avaliadas prospectiva e consecutivamente 43 pacientes com úlcera duodenal ao longo de 6 anos (7,2 pacientes por ano). A avaliação consistiu de questionário clínico de sintomas dispépticos, exame físico e endoscopia digestiva com biópsias gástricas para exame histológico e detecção do Helicobacter pylori. RESULTADOS: A idade no diagnóstico variou de 4 anos e 8 meses a 17 anos e 4 meses (mediana = 12 anos e 4 meses). O sintoma mais freqüente foi dor abdominal (39/43, 90,7%): no epigástrio em 31/39, periumbilical em 7/39 e noturna em 27/39. Outros sintomas freqüentes foram: diminuição do apetite (32/43, 74,4%), vômitos (30/43, 69,8%), plenitude pós-prandial (23/43, 53,5%), perda de peso (22/43, 51,2%) e sensibilidade abdominal (19/43, 44,2%). Hemorragia digestiva alta ocorreu em 19/43 pacientes (44,2%), e anemia em 21/43 (48,8%). H. pylori foi detectado em 41/43 (95,3%), e todos esses pacientes apresentaram gastrite crônica ativa de antro, 92% deles com predomínio do infiltrado linfomononuclear. A erradicação da bactéria ocorreu em 68,3% dos pacientes infectados, mas houve cicatrização da lesão em 100% dos pacientes erradicados e em 89% dos não-erradicados. CONCLUSÃO: Úlcera duodenal foi associada à gastrite crônica por H. pylori na grande maioria dos pacientes. Houve grande freqüência de complicações, especialmente hemorragia digestiva alta.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUNIFESP, EPMSciELOSociedade Brasileira de PediatriaUniversidade Federal de São Paulo (UNIFESP)Kawakami, Elisabete [UNIFESP]Machado, Rodrigo S. [UNIFESP]Fonseca, Jacqueline A. [UNIFESP]Patricio, Francy Reis da Silva [UNIFESP]2015-06-14T13:31:13Z2015-06-14T13:31:13Z2004-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion321-325application/pdfhttp://dx.doi.org/10.1590/S0021-75572004000500013Jornal de Pediatria. Sociedade Brasileira de Pediatria, v. 80, n. 4, p. 321-325, 2004.10.1590/S0021-75572004000500013S0021-75572004000500013.pdf0021-7557S0021-75572004000500013http://repositorio.unifesp.br/handle/11600/2173porJornal de Pediatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-10-14T10:59:59Zoai:repositorio.unifesp.br/:11600/2173Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-10-14T10:59:59Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes Clinical and histological features of duodenal ulcer in children and adolescents |
title |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes |
spellingShingle |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes Kawakami, Elisabete [UNIFESP] Peptic ulcer dyspepsia Helicobacter pylori Children Úlcera péptica dispepsia gastrite Helicobacter pylori |
title_short |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes |
title_full |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes |
title_fullStr |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes |
title_full_unstemmed |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes |
title_sort |
Aspectos clínicos e histológicos da úlcera duodenal em crianças e adolescentes |
author |
Kawakami, Elisabete [UNIFESP] |
author_facet |
Kawakami, Elisabete [UNIFESP] Machado, Rodrigo S. [UNIFESP] Fonseca, Jacqueline A. [UNIFESP] Patricio, Francy Reis da Silva [UNIFESP] |
author_role |
author |
author2 |
Machado, Rodrigo S. [UNIFESP] Fonseca, Jacqueline A. [UNIFESP] Patricio, Francy Reis da Silva [UNIFESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Kawakami, Elisabete [UNIFESP] Machado, Rodrigo S. [UNIFESP] Fonseca, Jacqueline A. [UNIFESP] Patricio, Francy Reis da Silva [UNIFESP] |
dc.subject.por.fl_str_mv |
Peptic ulcer dyspepsia Helicobacter pylori Children Úlcera péptica dispepsia gastrite Helicobacter pylori |
topic |
Peptic ulcer dyspepsia Helicobacter pylori Children Úlcera péptica dispepsia gastrite Helicobacter pylori |
description |
OBJECTIVE: To evaluate clinical and histological features of duodenal ulcer in children and adolescents. METHODS: Forty-three children with duodenal ulcer were prospectively and consecutively evaluated in a 6-year period (7.2 patients per year). Evaluation included clinical questionnaire focused on dyspeptic symptoms, physical examination, and digestive endoscopy with gastric biopsies for histological examination and Helicobacter pylori detection. RESULTS: Diagnostic age ranged from 4 years and 8 months to 17 years and 4 months (mean age: 12 years and 4 months). Abdominal pain was the main symptom (39/43, 90.7%), which was epigastric in 31/39, periumbilical in 7/39, and nocturnal in 27/39. Other symptoms were loss of appetite (32/43, 74.4%), vomiting (30/43, 69.8%), postprandial fullness (23/43, 53.5%), weight loss (22/43, 51.2%), and abdominal tenderness (19/43, 44.2%). Upper gastrointestinal bleeding occurred in 19/43 (44.2%), whereas anemia occurred in (21/43, 48.8%). Helicobacter pylori infection was detected in 41/43 (95.3%). All infected patients presented acute chronic gastritis in antrum, with lymphomononuclear infiltrate predominance in 92% of them. Eradication of the bacterium occurred in 68.3%. Ulcer healing occurred in all eradicated patients and in 89% of non-eradicated patients. CONCLUSION: Duodenal ulcer was associated with chronic gastritis due to Helicobacter pylori in the majority of patients. Many complications occurred, especially upper digestive bleeding. |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004-08-01 2015-06-14T13:31:13Z 2015-06-14T13:31:13Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0021-75572004000500013 Jornal de Pediatria. Sociedade Brasileira de Pediatria, v. 80, n. 4, p. 321-325, 2004. 10.1590/S0021-75572004000500013 S0021-75572004000500013.pdf 0021-7557 S0021-75572004000500013 http://repositorio.unifesp.br/handle/11600/2173 |
url |
http://dx.doi.org/10.1590/S0021-75572004000500013 http://repositorio.unifesp.br/handle/11600/2173 |
identifier_str_mv |
Jornal de Pediatria. Sociedade Brasileira de Pediatria, v. 80, n. 4, p. 321-325, 2004. 10.1590/S0021-75572004000500013 S0021-75572004000500013.pdf 0021-7557 S0021-75572004000500013 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Jornal de Pediatria |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
321-325 application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268453157076992 |