Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata
Autor(a) principal: | |
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Data de Publicação: | 1999 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/S0100-69911999000100006 http://repositorio.unifesp.br/handle/11600/732 |
Resumo: | The treatment of patients with adenocarcinoma of the prostate is based on the tumor stage and grade. For this reason the interpretation of the biopsy especimen is crucial and demands a great expertize from its examiner. ln order to define the accuracy of biopsy interpretation we settled the present study, trying to correlate the relationship between the histological grade of the biopsy especimens and the definitive pathological report read by the same pathologist. One hundred and twenty patients with localized prostate cancer stages TI - T3a submitted to radical prostatectomy were evaluated. The histological grade of the tumor was defined using the Gleason score sistem and a correlation was made between the score of biopsy and the surgical especimens. Complete agreement of the Gleason score was seen in 39 patients (32,5%) and if 1 digit discordance (± 1 Gleason score) was not considered, agreement was seen in 81 patients (67,5%). Seventy five tumors (62,5%) were undergraded and the rate of discordance was more common in patients with grade 2 to 4 tumors. According to our date, we conclude that the histological evaluation of the biopsy especimen in prostate cancer tends to underevaluate the true Gleason score of the tumor. |
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Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostataCorrelation between histologic biopsy grading and radical prostatectomy specimen in prostate cancerProstate cancerProstate biopsyGleason scoreCâncer da próstataBiópsia da próstataEscore de GleasonThe treatment of patients with adenocarcinoma of the prostate is based on the tumor stage and grade. For this reason the interpretation of the biopsy especimen is crucial and demands a great expertize from its examiner. ln order to define the accuracy of biopsy interpretation we settled the present study, trying to correlate the relationship between the histological grade of the biopsy especimens and the definitive pathological report read by the same pathologist. One hundred and twenty patients with localized prostate cancer stages TI - T3a submitted to radical prostatectomy were evaluated. The histological grade of the tumor was defined using the Gleason score sistem and a correlation was made between the score of biopsy and the surgical especimens. Complete agreement of the Gleason score was seen in 39 patients (32,5%) and if 1 digit discordance (± 1 Gleason score) was not considered, agreement was seen in 81 patients (67,5%). Seventy five tumors (62,5%) were undergraded and the rate of discordance was more common in patients with grade 2 to 4 tumors. According to our date, we conclude that the histological evaluation of the biopsy especimen in prostate cancer tends to underevaluate the true Gleason score of the tumor.Foram estudados, retrospectivamente, os prontuários de 120 pacientes com câncer localizado da próstata nos estádios clínicos T1, T2 e T3a e que foram submetidos a 1infadenectomia ilíaca e a cirurgia radical da próstata. Todos haviam sido graduados pela escala de Gleason através de biópsias da próstata guiadas pela ultra-sonografia transretal. Correlacionamos a graduação histo1ógica destas biópsias da próstata com a graduação final obtida no exame da peça cirúrgica correspondente e obtivemos exata concordância em 39 pacientes (32,50%). Ao considerarmos a concordância de ± 1unidade, observamos concordância de resultado em 81 pacientes (67,50%). A subgraduação histológica das biópsias prostáticas foi encontrada em 75 pacientes (62,50%) dos casos.UNIFESP-EPMHospital Sírio LibanêsFMUSP Departamento de PatologiaUNIFESP, EPMSciELOColégio Brasileiro de CirurgiõesUniversidade Federal de São Paulo (UNIFESP)Hospital Sírio LibanêsUniversidade de São Paulo (USP)Cury, José [UNIFESP]Srougi, Miguel [UNIFESP]Leite, Kátia Ramos Moreira [UNIFESP]Lopes, Luiz Heraldo CamaraCarneiro, Paulo Campos2015-06-14T13:24:50Z2015-06-14T13:24:50Z1999-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion21-26application/pdfhttp://dx.doi.org/10.1590/S0100-69911999000100006Revista do Colégio Brasileiro de Cirurgiões. Colégio Brasileiro de Cirurgiões, v. 26, n. 1, p. 21-26, 1999.10.1590/S0100-69911999000100006S0100-69911999000100006.pdf0100-6991S0100-69911999000100006http://repositorio.unifesp.br/handle/11600/732porRevista do Colégio Brasileiro de Cirurgiõesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T05:36:01Zoai:repositorio.unifesp.br/:11600/732Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-05T05:36:01Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata Correlation between histologic biopsy grading and radical prostatectomy specimen in prostate cancer |
title |
Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata |
spellingShingle |
Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata Cury, José [UNIFESP] Prostate cancer Prostate biopsy Gleason score Câncer da próstata Biópsia da próstata Escore de Gleason |
title_short |
Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata |
title_full |
Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata |
title_fullStr |
Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata |
title_full_unstemmed |
Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata |
title_sort |
Correlação entre a graduação histológica de biópsias e do espécimen cirúrgico em câncer da prostata |
author |
Cury, José [UNIFESP] |
author_facet |
Cury, José [UNIFESP] Srougi, Miguel [UNIFESP] Leite, Kátia Ramos Moreira [UNIFESP] Lopes, Luiz Heraldo Camara Carneiro, Paulo Campos |
author_role |
author |
author2 |
Srougi, Miguel [UNIFESP] Leite, Kátia Ramos Moreira [UNIFESP] Lopes, Luiz Heraldo Camara Carneiro, Paulo Campos |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Hospital Sírio Libanês Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Cury, José [UNIFESP] Srougi, Miguel [UNIFESP] Leite, Kátia Ramos Moreira [UNIFESP] Lopes, Luiz Heraldo Camara Carneiro, Paulo Campos |
dc.subject.por.fl_str_mv |
Prostate cancer Prostate biopsy Gleason score Câncer da próstata Biópsia da próstata Escore de Gleason |
topic |
Prostate cancer Prostate biopsy Gleason score Câncer da próstata Biópsia da próstata Escore de Gleason |
description |
The treatment of patients with adenocarcinoma of the prostate is based on the tumor stage and grade. For this reason the interpretation of the biopsy especimen is crucial and demands a great expertize from its examiner. ln order to define the accuracy of biopsy interpretation we settled the present study, trying to correlate the relationship between the histological grade of the biopsy especimens and the definitive pathological report read by the same pathologist. One hundred and twenty patients with localized prostate cancer stages TI - T3a submitted to radical prostatectomy were evaluated. The histological grade of the tumor was defined using the Gleason score sistem and a correlation was made between the score of biopsy and the surgical especimens. Complete agreement of the Gleason score was seen in 39 patients (32,5%) and if 1 digit discordance (± 1 Gleason score) was not considered, agreement was seen in 81 patients (67,5%). Seventy five tumors (62,5%) were undergraded and the rate of discordance was more common in patients with grade 2 to 4 tumors. According to our date, we conclude that the histological evaluation of the biopsy especimen in prostate cancer tends to underevaluate the true Gleason score of the tumor. |
publishDate |
1999 |
dc.date.none.fl_str_mv |
1999-02-01 2015-06-14T13:24:50Z 2015-06-14T13:24:50Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0100-69911999000100006 Revista do Colégio Brasileiro de Cirurgiões. Colégio Brasileiro de Cirurgiões, v. 26, n. 1, p. 21-26, 1999. 10.1590/S0100-69911999000100006 S0100-69911999000100006.pdf 0100-6991 S0100-69911999000100006 http://repositorio.unifesp.br/handle/11600/732 |
url |
http://dx.doi.org/10.1590/S0100-69911999000100006 http://repositorio.unifesp.br/handle/11600/732 |
identifier_str_mv |
Revista do Colégio Brasileiro de Cirurgiões. Colégio Brasileiro de Cirurgiões, v. 26, n. 1, p. 21-26, 1999. 10.1590/S0100-69911999000100006 S0100-69911999000100006.pdf 0100-6991 S0100-69911999000100006 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista do Colégio Brasileiro de Cirurgiões |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
21-26 application/pdf |
dc.publisher.none.fl_str_mv |
Colégio Brasileiro de Cirurgiões |
publisher.none.fl_str_mv |
Colégio Brasileiro de Cirurgiões |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268378674626560 |