Successful birth after intrafallopian transfer of microhatched embryos

• Autor(a) principal: Castellotti, Daniella Spilborghs
• Data de Publicação: 1997
• Outros Autores: Motta, Eduardo Leme Alves da [UNIFESP], Alegretti, José Roberto, Tran, Cuong, Serafini, Paulo
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://repositorio.unifesp.br/handle/11600/25766; http://dx.doi.org/10.1016/S0015-0282(97)81531-2
• topic: assisted hatching; zygote intrafallopian transfer; microlaparoscopy; pregnancy

Objective: To present a successful transfer of microhatched embryos to the fallopian tubes via microlaparoscopy.Design: Case report.Setting: Private practice affiliated with a medical university.Patient: A 40-year-old woman with primary infertility, mildly elevated baseline FSH levels, and a history of poor ovarian response to ovulation induction. Her husband had severe oligoospermia after vasectomy reversal.Intervention(s): Late luteal leuprolide acetate to pituitary down-regulation followed by pure FSH, 300 IU, and hMG, 300 IU, daily for ovulation induction. Transvaginal oocyte retrieval, intracytoplasmic sperm injection, assisted embryo hatching, microlaparoscopic intrafallopian ET.Main Outcome Measure(s): Amniocentesis at the 14th week of gestation revealed a normal karyotype (46,XX); birth of a normal female infant (3700 g).Result(s): Establishment of a single, viable intrauterine gestation followed by a vaginal delivery at term.Conclusion(s): This case shows the possibility of using assisted-hatched embryos for laparoscopic intrafallopian tube transfer. (C) 1997 by American Society for Reproductive Medicine.