Sebaceous hyperplasia: systemic treatment with isotretinoin

Detalhes bibliográficos
Autor(a) principal: Tagliolatto, Sandra
Data de Publicação: 2015
Outros Autores: Alchorne, Maurício Mota de Avelar [UNIFESP], Santos Neto, Octavio de Oliveira, Enokihara, Mauro Yoshiaki [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/abd1806-4841.20153192
http://repositorio.unifesp.br/handle/11600/38800
Resumo: The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. the average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. the statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study.
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spelling Sebaceous hyperplasia: systemic treatment with isotretinoinClinical trialIsotretinoinSebaceous Gland DiseasesTherapiesinvestigationalThe study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. the average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. the statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study.Private clin, Campinas, SP, BrazilUniv Estadual Campinas UNICAMP, Campinas, SP, BrazilUniversidade Federal de São Paulo UNIFESP, São Paulo, SP, BrazilUniversidade Federal de São Paulo UNIFESP, São Paulo, SP, BrazilWeb of ScienceFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Soc Brasileira DermatologiaPrivate clinUniversidade Estadual de Campinas (UNICAMP)Universidade Federal de São Paulo (UNIFESP)Tagliolatto, SandraAlchorne, Maurício Mota de Avelar [UNIFESP]Santos Neto, Octavio de OliveiraEnokihara, Mauro Yoshiaki [UNIFESP]2016-01-24T14:40:07Z2016-01-24T14:40:07Z2015-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion211-215application/pdfhttp://dx.doi.org/10.1590/abd1806-4841.20153192Anais Brasileiros de Dermatologia. Rio de Janeiro Rj: Soc Brasileira Dermatologia, v. 90, n. 2, p. 211-215, 2015.10.1590/abd1806-4841.20153192S0365-05962015000200211.pdf0365-0596S0365-05962015000200211http://repositorio.unifesp.br/handle/11600/38800WOS:000352211800008engAnais Brasileiros de Dermatologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-08T20:09:41Zoai:repositorio.unifesp.br/:11600/38800Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-08T20:09:41Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Sebaceous hyperplasia: systemic treatment with isotretinoin
title Sebaceous hyperplasia: systemic treatment with isotretinoin
spellingShingle Sebaceous hyperplasia: systemic treatment with isotretinoin
Tagliolatto, Sandra
Clinical trial
Isotretinoin
Sebaceous Gland Diseases
Therapies
investigational
title_short Sebaceous hyperplasia: systemic treatment with isotretinoin
title_full Sebaceous hyperplasia: systemic treatment with isotretinoin
title_fullStr Sebaceous hyperplasia: systemic treatment with isotretinoin
title_full_unstemmed Sebaceous hyperplasia: systemic treatment with isotretinoin
title_sort Sebaceous hyperplasia: systemic treatment with isotretinoin
author Tagliolatto, Sandra
author_facet Tagliolatto, Sandra
Alchorne, Maurício Mota de Avelar [UNIFESP]
Santos Neto, Octavio de Oliveira
Enokihara, Mauro Yoshiaki [UNIFESP]
author_role author
author2 Alchorne, Maurício Mota de Avelar [UNIFESP]
Santos Neto, Octavio de Oliveira
Enokihara, Mauro Yoshiaki [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Private clin
Universidade Estadual de Campinas (UNICAMP)
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Tagliolatto, Sandra
Alchorne, Maurício Mota de Avelar [UNIFESP]
Santos Neto, Octavio de Oliveira
Enokihara, Mauro Yoshiaki [UNIFESP]
dc.subject.por.fl_str_mv Clinical trial
Isotretinoin
Sebaceous Gland Diseases
Therapies
investigational
topic Clinical trial
Isotretinoin
Sebaceous Gland Diseases
Therapies
investigational
description The study aimed to verify the therapeutic action of isotretinoin in the treatment of sebaceous hyperplasia. During two months, 20 patients with sebaceous hyperplasia took isotretinoin at a dosage of 1mg/kg per day. Their skin lesions were counted and photographed before and after treatment and re-evaluated two years later. the average number of sebaceous hyperplasia lesions before treatment was 24 per patient. At the end of two months of therapy, the number of lesions decreased to 2 per patient. the statistically analyzed data showed a reduction in the number of lesions following isotretinoin use (p < 0.05). Two years after the end of the treatment, the average number of sebaceous hyperplasia lesions was 4 per patient. There were no severe side effects. Thus, the data analysis suggests that isotretinoin is a safe and effective drug for treating the disease under study.
publishDate 2015
dc.date.none.fl_str_mv 2015-03-01
2016-01-24T14:40:07Z
2016-01-24T14:40:07Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/abd1806-4841.20153192
Anais Brasileiros de Dermatologia. Rio de Janeiro Rj: Soc Brasileira Dermatologia, v. 90, n. 2, p. 211-215, 2015.
10.1590/abd1806-4841.20153192
S0365-05962015000200211.pdf
0365-0596
S0365-05962015000200211
http://repositorio.unifesp.br/handle/11600/38800
WOS:000352211800008
url http://dx.doi.org/10.1590/abd1806-4841.20153192
http://repositorio.unifesp.br/handle/11600/38800
identifier_str_mv Anais Brasileiros de Dermatologia. Rio de Janeiro Rj: Soc Brasileira Dermatologia, v. 90, n. 2, p. 211-215, 2015.
10.1590/abd1806-4841.20153192
S0365-05962015000200211.pdf
0365-0596
S0365-05962015000200211
WOS:000352211800008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Anais Brasileiros de Dermatologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 211-215
application/pdf
dc.publisher.none.fl_str_mv Soc Brasileira Dermatologia
publisher.none.fl_str_mv Soc Brasileira Dermatologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268460290539520

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