Analysis of the inflammatory response in endovascular treatment of aortic aneurysms

Detalhes bibliográficos
Autor(a) principal: Gabriel, Edmo Atique [UNIFESP]
Data de Publicação: 2007
Outros Autores: Locali, Rafael Fagionato, Romano, Carta Cristina, Duarte, Alberto Jose da Silva [UNIFESP], Fonseca, José Honório de Almeida Palma da [UNIFESP], Buffolo, Enio [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1016/j.ejcts.2006.11.053
http://repositorio.unifesp.br/handle/11600/29514
Resumo: Objective: the objective of this study is to evaluate the inflammatory response caused by endovascular stents in the treatment of aortic aneurysms. Methods: Twenty-five patients underwent endovascular stent treatment from March through December 2005. the evolution of mediators (sedimentation velocity, C reactive protein, interteukin-6, interleukin-8, tumor necrosis factor-alpha, intercellular adhesion molecule-1, L-selectin), inflammatory cells (leukocytes, lymphocytes, platelets), serum creatinine and body temperature within preoperative period and in the following postoperative periods - 1, 6, 24 and 48 h, 7 days, 1-3 months, was analyzed. in order to achieve statistic significance, Friedman test and Wilcoxon test were used, with index of significance of 5% (p < 0.05). Results: Peak values of sedimentation velocity, C reactive protein and interleukin-6 were observed at 7 days (p < 0.0001), 48 h (p < 0.0001) and 24 h (p < 0.0001), respectively. Tumor necrosis factor-alpha and interteukin-8 did not show statistically significant variability during the entire follow-up. in terms of intercellular adhesion molecule-1 and L-selectin, their expressive values were found in late phase of follow-up, although without statistical significance. Elevation of leukocytes count occurred in premature phase of follow-up (p < 0.0001), while lymphocyte and platelet count occurred in a late phase of follow-up (p < 0.0001). Serum levels of creatinine did not show significant variability during follow-up. the period between 24 and 48 h corresponded to major frequency for fever (p < 0.0001). Conclusion: Individual mediators analysis and inflammatory cells demonstrated variability of their values during postoperative follow-up. This could help in the analysis of the inflammatory response evolution caused by endovascular stent treatment for aortic aneurysms in premature and late phases after implantation of the vascular prosthesis. (c) 2007 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
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spelling Analysis of the inflammatory response in endovascular treatment of aortic aneurysmsaortic aneurysmvascular prosthesisinflammatory mediatorsObjective: the objective of this study is to evaluate the inflammatory response caused by endovascular stents in the treatment of aortic aneurysms. Methods: Twenty-five patients underwent endovascular stent treatment from March through December 2005. the evolution of mediators (sedimentation velocity, C reactive protein, interteukin-6, interleukin-8, tumor necrosis factor-alpha, intercellular adhesion molecule-1, L-selectin), inflammatory cells (leukocytes, lymphocytes, platelets), serum creatinine and body temperature within preoperative period and in the following postoperative periods - 1, 6, 24 and 48 h, 7 days, 1-3 months, was analyzed. in order to achieve statistic significance, Friedman test and Wilcoxon test were used, with index of significance of 5% (p < 0.05). Results: Peak values of sedimentation velocity, C reactive protein and interleukin-6 were observed at 7 days (p < 0.0001), 48 h (p < 0.0001) and 24 h (p < 0.0001), respectively. Tumor necrosis factor-alpha and interteukin-8 did not show statistically significant variability during the entire follow-up. in terms of intercellular adhesion molecule-1 and L-selectin, their expressive values were found in late phase of follow-up, although without statistical significance. Elevation of leukocytes count occurred in premature phase of follow-up (p < 0.0001), while lymphocyte and platelet count occurred in a late phase of follow-up (p < 0.0001). Serum levels of creatinine did not show significant variability during follow-up. the period between 24 and 48 h corresponded to major frequency for fever (p < 0.0001). Conclusion: Individual mediators analysis and inflammatory cells demonstrated variability of their values during postoperative follow-up. This could help in the analysis of the inflammatory response evolution caused by endovascular stent treatment for aortic aneurysms in premature and late phases after implantation of the vascular prosthesis. (c) 2007 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.Universidade Federal de São Paulo, Heart Hosp São Paulo, Paulista Sch Med, Div Cardiovasc Surg,Trop Illnessess Inst, São Paulo, BrazilUniversidade Federal de São Paulo, Heart Hosp São Paulo, Paulista Sch Med, Div Cardiovasc Surg,Trop Illnessess Inst, São Paulo, BrazilWeb of ScienceElsevier B.V.Universidade Federal de São Paulo (UNIFESP)Gabriel, Edmo Atique [UNIFESP]Locali, Rafael FagionatoRomano, Carta CristinaDuarte, Alberto Jose da Silva [UNIFESP]Fonseca, José Honório de Almeida Palma da [UNIFESP]Buffolo, Enio [UNIFESP]2016-01-24T12:41:53Z2016-01-24T12:41:53Z2007-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion406-412http://dx.doi.org/10.1016/j.ejcts.2006.11.053European Journal of Cardio-thoracic Surgery. Amsterdam: Elsevier B.V., v. 31, n. 3, p. 406-412, 2007.10.1016/j.ejcts.2006.11.0531010-7940http://repositorio.unifesp.br/handle/11600/29514WOS:000245794500017engEuropean Journal of Cardio-thoracic Surgeryinfo:eu-repo/semantics/openAccesshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2022-02-18T10:09:40Zoai:repositorio.unifesp.br/:11600/29514Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652022-02-18T10:09:40Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Analysis of the inflammatory response in endovascular treatment of aortic aneurysms
title Analysis of the inflammatory response in endovascular treatment of aortic aneurysms
spellingShingle Analysis of the inflammatory response in endovascular treatment of aortic aneurysms
Gabriel, Edmo Atique [UNIFESP]
aortic aneurysm
vascular prosthesis
inflammatory mediators
title_short Analysis of the inflammatory response in endovascular treatment of aortic aneurysms
title_full Analysis of the inflammatory response in endovascular treatment of aortic aneurysms
title_fullStr Analysis of the inflammatory response in endovascular treatment of aortic aneurysms
title_full_unstemmed Analysis of the inflammatory response in endovascular treatment of aortic aneurysms
title_sort Analysis of the inflammatory response in endovascular treatment of aortic aneurysms
author Gabriel, Edmo Atique [UNIFESP]
author_facet Gabriel, Edmo Atique [UNIFESP]
Locali, Rafael Fagionato
Romano, Carta Cristina
Duarte, Alberto Jose da Silva [UNIFESP]
Fonseca, José Honório de Almeida Palma da [UNIFESP]
Buffolo, Enio [UNIFESP]
author_role author
author2 Locali, Rafael Fagionato
Romano, Carta Cristina
Duarte, Alberto Jose da Silva [UNIFESP]
Fonseca, José Honório de Almeida Palma da [UNIFESP]
Buffolo, Enio [UNIFESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Gabriel, Edmo Atique [UNIFESP]
Locali, Rafael Fagionato
Romano, Carta Cristina
Duarte, Alberto Jose da Silva [UNIFESP]
Fonseca, José Honório de Almeida Palma da [UNIFESP]
Buffolo, Enio [UNIFESP]
dc.subject.por.fl_str_mv aortic aneurysm
vascular prosthesis
inflammatory mediators
topic aortic aneurysm
vascular prosthesis
inflammatory mediators
description Objective: the objective of this study is to evaluate the inflammatory response caused by endovascular stents in the treatment of aortic aneurysms. Methods: Twenty-five patients underwent endovascular stent treatment from March through December 2005. the evolution of mediators (sedimentation velocity, C reactive protein, interteukin-6, interleukin-8, tumor necrosis factor-alpha, intercellular adhesion molecule-1, L-selectin), inflammatory cells (leukocytes, lymphocytes, platelets), serum creatinine and body temperature within preoperative period and in the following postoperative periods - 1, 6, 24 and 48 h, 7 days, 1-3 months, was analyzed. in order to achieve statistic significance, Friedman test and Wilcoxon test were used, with index of significance of 5% (p < 0.05). Results: Peak values of sedimentation velocity, C reactive protein and interleukin-6 were observed at 7 days (p < 0.0001), 48 h (p < 0.0001) and 24 h (p < 0.0001), respectively. Tumor necrosis factor-alpha and interteukin-8 did not show statistically significant variability during the entire follow-up. in terms of intercellular adhesion molecule-1 and L-selectin, their expressive values were found in late phase of follow-up, although without statistical significance. Elevation of leukocytes count occurred in premature phase of follow-up (p < 0.0001), while lymphocyte and platelet count occurred in a late phase of follow-up (p < 0.0001). Serum levels of creatinine did not show significant variability during follow-up. the period between 24 and 48 h corresponded to major frequency for fever (p < 0.0001). Conclusion: Individual mediators analysis and inflammatory cells demonstrated variability of their values during postoperative follow-up. This could help in the analysis of the inflammatory response evolution caused by endovascular stent treatment for aortic aneurysms in premature and late phases after implantation of the vascular prosthesis. (c) 2007 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.
publishDate 2007
dc.date.none.fl_str_mv 2007-03-01
2016-01-24T12:41:53Z
2016-01-24T12:41:53Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1016/j.ejcts.2006.11.053
European Journal of Cardio-thoracic Surgery. Amsterdam: Elsevier B.V., v. 31, n. 3, p. 406-412, 2007.
10.1016/j.ejcts.2006.11.053
1010-7940
http://repositorio.unifesp.br/handle/11600/29514
WOS:000245794500017
url http://dx.doi.org/10.1016/j.ejcts.2006.11.053
http://repositorio.unifesp.br/handle/11600/29514
identifier_str_mv European Journal of Cardio-thoracic Surgery. Amsterdam: Elsevier B.V., v. 31, n. 3, p. 406-412, 2007.
10.1016/j.ejcts.2006.11.053
1010-7940
WOS:000245794500017
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv European Journal of Cardio-thoracic Surgery
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
eu_rights_str_mv openAccess
rights_invalid_str_mv http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.format.none.fl_str_mv 406-412
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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