First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil

Detalhes bibliográficos
Autor(a) principal: Lincopan, Nilton
Data de Publicação: 2005
Outros Autores: McCulloch, John Anthony, Reinert, Cristina, Cassettari, Valeria C., Gales, Ana C [UNIFESP], Mamizuka, Elsa M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1128/JCM.43.1.516-519.2005
http://repositorio.unifesp.br/handle/11600/28064
Resumo: A multiresistant Klebsiella pneumoniae isolate was taken from the blood of a 75-year-old patient with nosocomial pneumonia who developed septic shock and failed therapy with imipenem. the isolate presented an MIC of imipenem of 128 mug/ml, and the production of a metallo-beta-lactamase was confirmed by phenotypic and genotypic techniques. We here report, for the first time, the detection of a metalloenzyme (IMP-1) -producing K. pneumoniae clinical strain in Latin America. the gene responsible for this phenotype was found to be bla(IMP-1), carried in a class 1 integron.
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spelling First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in BrazilA multiresistant Klebsiella pneumoniae isolate was taken from the blood of a 75-year-old patient with nosocomial pneumonia who developed septic shock and failed therapy with imipenem. the isolate presented an MIC of imipenem of 128 mug/ml, and the production of a metallo-beta-lactamase was confirmed by phenotypic and genotypic techniques. We here report, for the first time, the detection of a metalloenzyme (IMP-1) -producing K. pneumoniae clinical strain in Latin America. the gene responsible for this phenotype was found to be bla(IMP-1), carried in a class 1 integron.Univ São Paulo, Fac Ciencias Farmaceut, Dept Anal Clin, BR-05508900 São Paulo, BrazilUniv São Paulo, Univ Hosp, Commissao Controle Infeccao Hosp, BR-05508900 São Paulo, BrazilUniversidade Federal de São Paulo, Disciplina Doencas Infecc & Parasitarias, Lab Especial Microbiol Clin, São Paulo, BrazilUniversidade Federal de São Paulo, Disciplina Doencas Infecc & Parasitarias, Lab Especial Microbiol Clin, São Paulo, BrazilWeb of ScienceAmer Soc MicrobiologyUniversidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)Lincopan, NiltonMcCulloch, John AnthonyReinert, CristinaCassettari, Valeria C.Gales, Ana C [UNIFESP]Mamizuka, Elsa M.2016-01-24T12:37:32Z2016-01-24T12:37:32Z2005-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion516-519application/pdfhttp://dx.doi.org/10.1128/JCM.43.1.516-519.2005Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 43, n. 1, p. 516-519, 2005.10.1128/JCM.43.1.516-519.2005WOS000226380400089.pdf0095-1137http://repositorio.unifesp.br/handle/11600/28064WOS:000226380400089engJournal of Clinical Microbiologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-30T16:09:23Zoai:repositorio.unifesp.br/:11600/28064Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-30T16:09:23Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil
title First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil
spellingShingle First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil
Lincopan, Nilton
title_short First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil
title_full First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil
title_fullStr First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil
title_full_unstemmed First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil
title_sort First isolation of metallo-beta-lactamase-producing multiresistant Klebsiella pneumoniae from a patient in Brazil
author Lincopan, Nilton
author_facet Lincopan, Nilton
McCulloch, John Anthony
Reinert, Cristina
Cassettari, Valeria C.
Gales, Ana C [UNIFESP]
Mamizuka, Elsa M.
author_role author
author2 McCulloch, John Anthony
Reinert, Cristina
Cassettari, Valeria C.
Gales, Ana C [UNIFESP]
Mamizuka, Elsa M.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade de São Paulo (USP)
Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Lincopan, Nilton
McCulloch, John Anthony
Reinert, Cristina
Cassettari, Valeria C.
Gales, Ana C [UNIFESP]
Mamizuka, Elsa M.
description A multiresistant Klebsiella pneumoniae isolate was taken from the blood of a 75-year-old patient with nosocomial pneumonia who developed septic shock and failed therapy with imipenem. the isolate presented an MIC of imipenem of 128 mug/ml, and the production of a metallo-beta-lactamase was confirmed by phenotypic and genotypic techniques. We here report, for the first time, the detection of a metalloenzyme (IMP-1) -producing K. pneumoniae clinical strain in Latin America. the gene responsible for this phenotype was found to be bla(IMP-1), carried in a class 1 integron.
publishDate 2005
dc.date.none.fl_str_mv 2005-01-01
2016-01-24T12:37:32Z
2016-01-24T12:37:32Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1128/JCM.43.1.516-519.2005
Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 43, n. 1, p. 516-519, 2005.
10.1128/JCM.43.1.516-519.2005
WOS000226380400089.pdf
0095-1137
http://repositorio.unifesp.br/handle/11600/28064
WOS:000226380400089
url http://dx.doi.org/10.1128/JCM.43.1.516-519.2005
http://repositorio.unifesp.br/handle/11600/28064
identifier_str_mv Journal of Clinical Microbiology. Washington: Amer Soc Microbiology, v. 43, n. 1, p. 516-519, 2005.
10.1128/JCM.43.1.516-519.2005
WOS000226380400089.pdf
0095-1137
WOS:000226380400089
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Clinical Microbiology
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 516-519
application/pdf
dc.publisher.none.fl_str_mv Amer Soc Microbiology
publisher.none.fl_str_mv Amer Soc Microbiology
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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