Frequency and clinical manifestations of post-poliomyelitis syndrome in a brazilian tertiary care center

• Autor(a) principal: Quadros, Abrahão Augusto Juviniano [UNIFESP]
• Data de Publicação: 2012
• Outros Autores: Conde, Mônica Tilli Reis Pessoa, Marin, Luis Fabiano [UNIFESP], Silva, Helga Cristina Almeida da [UNIFESP], Silva, Tatiana Mesquita e [UNIFESP], Paula, Maria Bernadete Eduardo de, Pereira, Roberto Dias Batista [UNIFESP], Ramos, Paulo Eduardo [UNIFESP], Abe, Gislane [UNIFESP], Oliveira, Acary Souza Bulle [UNIFESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0004-282X2012000800002; http://repositorio.unifesp.br/handle/11600/7242
• topic: post-polio syndrome; poliomyelitis; prevalence; síndrome pós-poliomielite; poliomielite; prevalência

OBJECTIVE: To determine the frequency and clinical manifestations of patients with post-poliomyelitis syndrome (PPS) in a Brazilian division of neuromuscular disorders. METHODS: A total of 167 patients with prior history of paralytic poliomyelitis was investigated for PPS, based on international diagnostic criteria. Other variables analyzed were: gender, race, age at poliomyelitis infection, age at PPS onset, and PPS symptoms. RESULTS: One hundred and twenty-nine patients presented PPS, corresponding to 77.2% of the studied population. 62.8% were women and 37.2% were men. Mean age of patients with PPS at onset of PPS symptoms was 39.9±9.69 years. Their main clinical manifestations were: new weakness in the previously affected limbs (69%) and in the apparently not affected limbs (31%); joint pain (79.8%); fatigue (77.5%); muscle pain (76%); and cold intolerance (69.8%). CONCLUSIONS: Most patients of our sample presented PPS. In Brazil, PPS frequency and clinical features are quite similar to those of other countries.