Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://repositorio.unifesp.br/handle/11600/55288 http://dx.doi.org/10.1590/1980-5373-MR-2016-0969 |
Resumo: | Rotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In opposite, electrospinning technique needs the presence of an external electric field to create fiber from the polymeric jet solution. This article investigates both processes using two different biocompatible polymers: Poly(L-lactic acid) (PLLA) and Poly(e-caprolactone) (PCL). Samples were characterized by scanning electron microscopy, thermogravimetric analysis, differential scanning calorimeter, and Fourier-transform infrared spectroscopy. Morphological observations showed the efficiency of both techniques in obtaining nanofibers. Thermal analyses of data indicate immiscible property of different blends and the total solvent evaporation. In vitro cytocompatibility test showed that RJS and electrospinning samples exhibited good cytocompatibility. Based on these results, it may be concluded that the fibers obtained with both technologies are non-cytotoxicity and with good biocompatibility, and might be suitable for applications as scaffold for cell growth. |
id |
UFSP_5da85928a4d2b0e04a2c24800456f58d |
---|---|
oai_identifier_str |
oai:repositorio.unifesp.br:11600/55288 |
network_acronym_str |
UFSP |
network_name_str |
Repositório Institucional da UNIFESP |
repository_id_str |
3465 |
spelling |
Vida, Talita AlmeidaMotta, Adriana CristinaSantos, Arnaldo Rodrigues, Jr.Cardoso, Guinea Brasil Camargode Brito, Crystopher Cardoso [UNIFESP]de Carvalho Zavaglia, Cecilia Amelia2020-07-17T14:03:18Z2020-07-17T14:03:18Z2017Materials Research-Ibero-American Journal Of Materials. Sao Carlos, v. 20, p. 910-916, 2017.1516-1439https://repositorio.unifesp.br/handle/11600/55288http://dx.doi.org/10.1590/1980-5373-MR-2016-0969S1516-14392017000800910.pdfS1516-1439201700080091010.1590/1980-5373-MR-2016-0969WOS:000430187600131Rotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In opposite, electrospinning technique needs the presence of an external electric field to create fiber from the polymeric jet solution. This article investigates both processes using two different biocompatible polymers: Poly(L-lactic acid) (PLLA) and Poly(e-caprolactone) (PCL). Samples were characterized by scanning electron microscopy, thermogravimetric analysis, differential scanning calorimeter, and Fourier-transform infrared spectroscopy. Morphological observations showed the efficiency of both techniques in obtaining nanofibers. Thermal analyses of data indicate immiscible property of different blends and the total solvent evaporation. In vitro cytocompatibility test showed that RJS and electrospinning samples exhibited good cytocompatibility. Based on these results, it may be concluded that the fibers obtained with both technologies are non-cytotoxicity and with good biocompatibility, and might be suitable for applications as scaffold for cell growth.CAPESFAPESPBiofabris-INCTBiomaterials Laboratory PUC/SP SorocabaUniv Estadual Campinas, Fac Engn Mecan, Campinas, SP, BrazilPontificia Univ Catolica, Sao Paulo, SP, BrazilUniv Fed ABC, Ctr Ciencias Nat & Humanas, Santo Andre, BrazilUniv Fed Sao Paulo, Dept Ciencias Mar, Santos, SP, BrazilUniv Fed Sao Paulo, Dept Ciencias Mar, Santos, SP, BrazilFAPESP: 2013/19372-0Web of Science910-916engUniv Fed Sao Carlos, Dept Engenharia MaterialsMaterials Research-Ibero-American Journal Of MaterialsRotary jet spinningElectrospinningBlendNanofibersBiomaterialsFibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinninginfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleSao Carlos20info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1516-14392017000800910.pdfapplication/pdf3663516${dspace.ui.url}/bitstream/11600/55288/1/S1516-14392017000800910.pdfc89a1244991c4b0f81810e9b3d4b94caMD51open accessTEXTS1516-14392017000800910.pdf.txtS1516-14392017000800910.pdf.txtExtracted texttext/plain28532${dspace.ui.url}/bitstream/11600/55288/5/S1516-14392017000800910.pdf.txt458c20274d262be7e9532efe6f05949bMD55open accessTHUMBNAILS1516-14392017000800910.pdf.jpgS1516-14392017000800910.pdf.jpgIM Thumbnailimage/jpeg6630${dspace.ui.url}/bitstream/11600/55288/7/S1516-14392017000800910.pdf.jpgc9c2f7757d30e27297420625b3282390MD57open access11600/552882023-06-05 19:39:38.112open accessoai:repositorio.unifesp.br:11600/55288Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-06-05T22:39:38Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning |
title |
Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning |
spellingShingle |
Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning Vida, Talita Almeida Rotary jet spinning Electrospinning Blend Nanofibers Biomaterials |
title_short |
Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning |
title_full |
Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning |
title_fullStr |
Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning |
title_full_unstemmed |
Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning |
title_sort |
Fibrous PCL/PLLA Scaffolds Obtained by Rotary Jet Spinning and Electrospinning |
author |
Vida, Talita Almeida |
author_facet |
Vida, Talita Almeida Motta, Adriana Cristina Santos, Arnaldo Rodrigues, Jr. Cardoso, Guinea Brasil Camargo de Brito, Crystopher Cardoso [UNIFESP] de Carvalho Zavaglia, Cecilia Amelia |
author_role |
author |
author2 |
Motta, Adriana Cristina Santos, Arnaldo Rodrigues, Jr. Cardoso, Guinea Brasil Camargo de Brito, Crystopher Cardoso [UNIFESP] de Carvalho Zavaglia, Cecilia Amelia |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Vida, Talita Almeida Motta, Adriana Cristina Santos, Arnaldo Rodrigues, Jr. Cardoso, Guinea Brasil Camargo de Brito, Crystopher Cardoso [UNIFESP] de Carvalho Zavaglia, Cecilia Amelia |
dc.subject.eng.fl_str_mv |
Rotary jet spinning Electrospinning Blend Nanofibers Biomaterials |
topic |
Rotary jet spinning Electrospinning Blend Nanofibers Biomaterials |
description |
Rotary jet spinning (RJS) and electrospinning are techniques to obtain fibrous scaffolds. RJS is a simple method, which fabricates three-dimensional fibers by exploiting a high-speed rotating nozzle, creating a polymer jet which stretches until solidification, and does not require high voltage. In opposite, electrospinning technique needs the presence of an external electric field to create fiber from the polymeric jet solution. This article investigates both processes using two different biocompatible polymers: Poly(L-lactic acid) (PLLA) and Poly(e-caprolactone) (PCL). Samples were characterized by scanning electron microscopy, thermogravimetric analysis, differential scanning calorimeter, and Fourier-transform infrared spectroscopy. Morphological observations showed the efficiency of both techniques in obtaining nanofibers. Thermal analyses of data indicate immiscible property of different blends and the total solvent evaporation. In vitro cytocompatibility test showed that RJS and electrospinning samples exhibited good cytocompatibility. Based on these results, it may be concluded that the fibers obtained with both technologies are non-cytotoxicity and with good biocompatibility, and might be suitable for applications as scaffold for cell growth. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2020-07-17T14:03:18Z |
dc.date.available.fl_str_mv |
2020-07-17T14:03:18Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Materials Research-Ibero-American Journal Of Materials. Sao Carlos, v. 20, p. 910-916, 2017. |
dc.identifier.uri.fl_str_mv |
https://repositorio.unifesp.br/handle/11600/55288 http://dx.doi.org/10.1590/1980-5373-MR-2016-0969 |
dc.identifier.issn.none.fl_str_mv |
1516-1439 |
dc.identifier.file.none.fl_str_mv |
S1516-14392017000800910.pdf |
dc.identifier.scielo.none.fl_str_mv |
S1516-14392017000800910 |
dc.identifier.doi.none.fl_str_mv |
10.1590/1980-5373-MR-2016-0969 |
dc.identifier.wos.none.fl_str_mv |
WOS:000430187600131 |
identifier_str_mv |
Materials Research-Ibero-American Journal Of Materials. Sao Carlos, v. 20, p. 910-916, 2017. 1516-1439 S1516-14392017000800910.pdf S1516-14392017000800910 10.1590/1980-5373-MR-2016-0969 WOS:000430187600131 |
url |
https://repositorio.unifesp.br/handle/11600/55288 http://dx.doi.org/10.1590/1980-5373-MR-2016-0969 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Materials Research-Ibero-American Journal Of Materials |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
910-916 |
dc.coverage.none.fl_str_mv |
Sao Carlos |
dc.publisher.none.fl_str_mv |
Univ Fed Sao Carlos, Dept Engenharia Materials |
publisher.none.fl_str_mv |
Univ Fed Sao Carlos, Dept Engenharia Materials |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
bitstream.url.fl_str_mv |
${dspace.ui.url}/bitstream/11600/55288/1/S1516-14392017000800910.pdf ${dspace.ui.url}/bitstream/11600/55288/5/S1516-14392017000800910.pdf.txt ${dspace.ui.url}/bitstream/11600/55288/7/S1516-14392017000800910.pdf.jpg |
bitstream.checksum.fl_str_mv |
c89a1244991c4b0f81810e9b3d4b94ca 458c20274d262be7e9532efe6f05949b c9c2f7757d30e27297420625b3282390 |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
_version_ |
1802764231368507392 |