Late auditory event-related evoked potential (P300) in Down's syndrome patients
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/11600/43141 http://dx.doi.org/10.1590/S1808-86942010000200010 |
Resumo: | Down syndrome is caused by a trisomy of chromosome 21 and is associated with central auditory processing deficit, learning disability and, probably, early-onset Alzheimer's disease. Aim: to evaluate the latencies and amplitudes of evoked late auditory potential related to P300 events and their changes in young adults with Down's syndrome. Materials and Method: Prospective case study. P300 test latency and amplitudes were evaluated in 17 individuals with Down's syndrome and 34 healthy individuals. Results: The P300 latency (N1, P2, N2 and P3) was longer and the N2-P3 amplitude was lower in individuals with Down syndrome when compared to those in the control group. Conclusion: In young adults with Down syndrome, N1, P2, N2 and P3 latencies of late auditory evoked potential related to P300 events were prolonged, and N2 - P3 amplitudes were significantly reduced, suggesting integration impairment between the auditory association area and cortical and subcortical areas of the central nervous system. |
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César, Carla Patricia Hernandez Alves Ribeiro [UNIFESP]Caovilla, Heloisa Helena [UNIFESP]Munhoz, Mário Sérgio Lei[UNIFESP]Ganança, Maurcio MalavasiUniversidade Federal de São Paulo (UNIFESP)Sao Paulo Bandeirante Univ2018-06-15T16:24:03Z2018-06-15T16:24:03Z2010-03-01Brazilian Journal Of Otorhinolaryngology. Sao Paulo: Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, v. 76, n. 2, p. 206-212, 2010.1808-8694http://repositorio.unifesp.br/11600/43141http://dx.doi.org/10.1590/S1808-86942010000200010S1808-86942010000200010-en.pdfS1808-86942010000200010-pt.pdfS1808-8694201000020001010.1590/S1808-86942010000200010WOS:000293572100010Down syndrome is caused by a trisomy of chromosome 21 and is associated with central auditory processing deficit, learning disability and, probably, early-onset Alzheimer's disease. Aim: to evaluate the latencies and amplitudes of evoked late auditory potential related to P300 events and their changes in young adults with Down's syndrome. Materials and Method: Prospective case study. P300 test latency and amplitudes were evaluated in 17 individuals with Down's syndrome and 34 healthy individuals. Results: The P300 latency (N1, P2, N2 and P3) was longer and the N2-P3 amplitude was lower in individuals with Down syndrome when compared to those in the control group. Conclusion: In young adults with Down syndrome, N1, P2, N2 and P3 latencies of late auditory evoked potential related to P300 events were prolonged, and N2 - P3 amplitudes were significantly reduced, suggesting integration impairment between the auditory association area and cortical and subcortical areas of the central nervous system.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Sao Paulo Methodist Univ, Speech Therapy Course, Sao Paulo, BrazilUniv Fed Sao Paulo, Paulista Med School, Otol & Otoneurol Discipline, Sao Paulo, BrazilSao Paulo Bandeirante Univ, Program Vestibular Rehabil & Social Inclus, Sao Paulo, BrazilUniv Fed Sao Paulo, Paulista Med School, Otol & Otoneurol Discipline, Sao Paulo, BrazilWeb of Science206-212engAssoc Brasileira Otorrinolaringologia & Cirurgia CervicofacialBrazilian Journal Of Otorhinolaryngologydown syndromep300event-related potentialsLate auditory event-related evoked potential (P300) in Down's syndrome patientsPotencial evocado auditivo tardio relacionado a eventos (P300) na síndrome de Downinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1808-86942010000200010-en.pdfapplication/pdf183753${dspace.ui.url}/bitstream/11600/43141/1/S1808-86942010000200010-en.pdfb4539b2bcd21d09afd53c86f557837f3MD51open accessS1808-86942010000200010-pt.pdfapplication/pdf194056${dspace.ui.url}/bitstream/11600/43141/2/S1808-86942010000200010-pt.pdff4d0daed7f3585fd67dbf6d9653ff569MD52open access11600/431412022-02-07 21:44:40.399open accessoai:repositorio.unifesp.br:11600/43141Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652022-02-08T00:44:40Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Late auditory event-related evoked potential (P300) in Down's syndrome patients |
dc.title.alternative.pt.fl_str_mv |
Potencial evocado auditivo tardio relacionado a eventos (P300) na síndrome de Down |
title |
Late auditory event-related evoked potential (P300) in Down's syndrome patients |
spellingShingle |
Late auditory event-related evoked potential (P300) in Down's syndrome patients César, Carla Patricia Hernandez Alves Ribeiro [UNIFESP] down syndrome p300 event-related potentials |
title_short |
Late auditory event-related evoked potential (P300) in Down's syndrome patients |
title_full |
Late auditory event-related evoked potential (P300) in Down's syndrome patients |
title_fullStr |
Late auditory event-related evoked potential (P300) in Down's syndrome patients |
title_full_unstemmed |
Late auditory event-related evoked potential (P300) in Down's syndrome patients |
title_sort |
Late auditory event-related evoked potential (P300) in Down's syndrome patients |
author |
César, Carla Patricia Hernandez Alves Ribeiro [UNIFESP] |
author_facet |
César, Carla Patricia Hernandez Alves Ribeiro [UNIFESP] Caovilla, Heloisa Helena [UNIFESP] Munhoz, Mário Sérgio Lei[UNIFESP] Ganança, Maurcio Malavasi |
author_role |
author |
author2 |
Caovilla, Heloisa Helena [UNIFESP] Munhoz, Mário Sérgio Lei[UNIFESP] Ganança, Maurcio Malavasi |
author2_role |
author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Sao Paulo Bandeirante Univ |
dc.contributor.author.fl_str_mv |
César, Carla Patricia Hernandez Alves Ribeiro [UNIFESP] Caovilla, Heloisa Helena [UNIFESP] Munhoz, Mário Sérgio Lei[UNIFESP] Ganança, Maurcio Malavasi |
dc.subject.eng.fl_str_mv |
down syndrome p300 event-related potentials |
topic |
down syndrome p300 event-related potentials |
description |
Down syndrome is caused by a trisomy of chromosome 21 and is associated with central auditory processing deficit, learning disability and, probably, early-onset Alzheimer's disease. Aim: to evaluate the latencies and amplitudes of evoked late auditory potential related to P300 events and their changes in young adults with Down's syndrome. Materials and Method: Prospective case study. P300 test latency and amplitudes were evaluated in 17 individuals with Down's syndrome and 34 healthy individuals. Results: The P300 latency (N1, P2, N2 and P3) was longer and the N2-P3 amplitude was lower in individuals with Down syndrome when compared to those in the control group. Conclusion: In young adults with Down syndrome, N1, P2, N2 and P3 latencies of late auditory evoked potential related to P300 events were prolonged, and N2 - P3 amplitudes were significantly reduced, suggesting integration impairment between the auditory association area and cortical and subcortical areas of the central nervous system. |
publishDate |
2010 |
dc.date.issued.fl_str_mv |
2010-03-01 |
dc.date.accessioned.fl_str_mv |
2018-06-15T16:24:03Z |
dc.date.available.fl_str_mv |
2018-06-15T16:24:03Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Brazilian Journal Of Otorhinolaryngology. Sao Paulo: Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, v. 76, n. 2, p. 206-212, 2010. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/11600/43141 http://dx.doi.org/10.1590/S1808-86942010000200010 |
dc.identifier.issn.none.fl_str_mv |
1808-8694 |
dc.identifier.file.none.fl_str_mv |
S1808-86942010000200010-en.pdf S1808-86942010000200010-pt.pdf |
dc.identifier.scielo.none.fl_str_mv |
S1808-86942010000200010 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S1808-86942010000200010 |
dc.identifier.wos.none.fl_str_mv |
WOS:000293572100010 |
identifier_str_mv |
Brazilian Journal Of Otorhinolaryngology. Sao Paulo: Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, v. 76, n. 2, p. 206-212, 2010. 1808-8694 S1808-86942010000200010-en.pdf S1808-86942010000200010-pt.pdf S1808-86942010000200010 10.1590/S1808-86942010000200010 WOS:000293572100010 |
url |
http://repositorio.unifesp.br/11600/43141 http://dx.doi.org/10.1590/S1808-86942010000200010 |
dc.language.iso.fl_str_mv |
eng |
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eng |
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Brazilian Journal Of Otorhinolaryngology |
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info:eu-repo/semantics/openAccess |
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openAccess |
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206-212 |
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Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial |
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Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial |
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