Injeção percutânea de etanol no tratamento de nódulos tiroidianos sólidos, císticos e autônomos

• Autor(a) principal: Bianchini, Elizabeth X. [UNIFESP]
• Data de Publicação: 2003
• Outros Autores: Ikejiri, Elza S. [UNIFESP], Mamone, Maria Conceição [UNIFESP], Paiva, Elias R. [UNIFESP], Maciel, Rui Monteiro de Barros [UNIFESP], Furlanetto, Reinaldo P. [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0004-27302003000500007; http://repositorio.unifesp.br/handle/11600/1851
• topic: Ethanol; Thyroid nodule; Interventional ultrasonography; Sclerotherapy; Thyrotoxicosis; Etanol; Nódulo tiroidiano; Ultrassonografia; Escleroterapia; Hipertiroidismo

Percutaneous ethanol injection (PEI) guided by ultrasound has been used for the treatment of cystic, solid and autonomous thyroid nodules. We present our experience in the treatment of 50 patients with thyroid nodules: 26 solid, 17 cystic and 7 autonomous (AN). Patients were evaluated 1 week, 1, 3, and 6 months and 1 year after PEI. After one year, solid nodules showed a mean 74% volume reduction, and cysts a volume reduction of 92%, with no recurrences. After one year, 5 patients with AN reached clinical and laboratory euthyroidism; the other 2 also became euthyroid, but with subnormal TSH. Recurrence of thyrotoxicosis was not observed and mean nodular reduction was 66%. The procedure was well tolerated by all patients. The results confirm that PEI is a good therapeutic alternative for reduction of solid and cystic thyroid nodules and for the treatment of autonomous nodules.