Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2016 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNIFESP |
| dARK ID: | ark:/48912/001300000qf0n |
| DOI: | 10.1055/s-0036-1586160 |
| Texto Completo: | http://dx.doi.org/10.1055/s-0036-1586160 https://repositorio.unifesp.br/handle/11600/57712 |
Resumo: | Objectives To identify the epidemiological risk factors for congenital anomalies (CAs) and the impact of these fetal malformations on the perinatal outcomes. Methods This prospective cohort study comprised 275 women whose fetuses had CAs. Maternal variables to establish potential risk factors for each group of CA and perinatal outcomes were evaluated. The primary outcome was CA. Secondary outcomes included: fetal growth restriction (FGR) |
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Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomaliespregnancycongenital anomalyepidemiological risk factorultrasoundperinatal outcomeObjectives To identify the epidemiological risk factors for congenital anomalies (CAs) and the impact of these fetal malformations on the perinatal outcomes. Methods This prospective cohort study comprised 275 women whose fetuses had CAs. Maternal variables to establish potential risk factors for each group of CA and perinatal outcomes were evaluated. The primary outcome was CA. Secondary outcomes included: fetal growth restriction (FGR)fetal distress (FD)premature rupture of membranes (PROM)oligohydramnios or polyhydramniospreterm delivery (PTD)stillbirthcesarean sectionlow birth weightApgar score < 7 at the 1st and 5th minutesneed for assisted ventilation at birthneonatal infectionneed for surgical treatmentearly neonatal deathand hospitalization time. Chi-square (chi(2)) test and multilevel regression analysis were applied to compare the groups and determine the effects of maternal characteristics on the incidence of CAs. Results The general prevalence of CAs was of 2.4%. Several maternal characteristics were associated to CAs, such as: ageskin colorlevel of educationparityfolic acid supplementationtobacco useand history of previous miscarriage. There were no significant differences among the CA groups in relation to FGR, FD, PROM, 1-minute Apgar score > 7, and need for assisted ventilation at birth. On the other hand, the prevalence of the other considered outcomes varied significantly among groups. Preterm delivery was significantly more frequent in gastrointestinal tract/abdominal wall defects. The stillbirth rate was increased in all CAs, mainly in isolated fetal hydrops (odds ratio [OR]: 27.1395% confidence interval [95% CI]: 2.90-253.47). Hospitalization time was higher for the urinary tract and congenital heart disease groups (p < 0.01). Neonatal death was significantly less frequent in the central nervous system anomalies group. Conclusion It was possible to identify several risk factors for CAs. Adverse perinatal outcomes were presented in all CA groups, and may differ according to the type of CA considered.Univ Sao Paulo, Fac Med Ribeirao Preto, Dept Gynecol & Obstet, Ribeirao Preto, SP, BrazilUniv Fed Sao Paulo, Dept Obstet, Sao Paulo, SP, BrazilUniv Fed Sao Paulo, Dept Obstet, Sao Paulo, SP, BrazilWeb of ScienceFederacao Brasileira Soc Ginecologia & Obstetricia-Febrasgo2020-08-14T13:44:31Z2020-08-14T13:44:31Z2016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion348-355application/pdfhttp://dx.doi.org/10.1055/s-0036-1586160Revista Brasileira De Ginecologia E Obstetricia. Rio De Janeiro Rj, v. 38, n. 7, p. 348-355, 2016.10.1055/s-0036-1586160WOS000410247300006.pdf0100-7203S0100-72032016000700348https://repositorio.unifesp.br/handle/11600/57712WOS:000410247300006ark:/48912/001300000qf0nengRevista Brasileira De Ginecologia E ObstetriciaRio De Janeiro Rjinfo:eu-repo/semantics/openAccessGarcia Almeida, Lissa FernandesAraujo Junior, Edward [UNIFESP]Crott, Gerson ClaudioOkido, Marcos MasaruBerezowski, Aderson TadeuDuarte, GeraldoMarcolin, Alessandra Cristinareponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-01T10:25:59Zoai:repositorio.unifesp.br/:11600/57712Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:31:05.991944Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
| dc.title.none.fl_str_mv |
Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies |
| title |
Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies |
| spellingShingle |
Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies Garcia Almeida, Lissa Fernandes pregnancy congenital anomaly epidemiological risk factor ultrasound perinatal outcome Garcia Almeida, Lissa Fernandes pregnancy congenital anomaly epidemiological risk factor ultrasound perinatal outcome |
| title_short |
Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies |
| title_full |
Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies |
| title_fullStr |
Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies |
| title_full_unstemmed |
Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies |
| title_sort |
Epidemiological Risk Factors and Perinatal Outcomes of Congenital Anomalies |
| author |
Garcia Almeida, Lissa Fernandes |
| author_facet |
Garcia Almeida, Lissa Fernandes Garcia Almeida, Lissa Fernandes Araujo Junior, Edward [UNIFESP] Crott, Gerson Claudio Okido, Marcos Masaru Berezowski, Aderson Tadeu Duarte, Geraldo Marcolin, Alessandra Cristina Araujo Junior, Edward [UNIFESP] Crott, Gerson Claudio Okido, Marcos Masaru Berezowski, Aderson Tadeu Duarte, Geraldo Marcolin, Alessandra Cristina |
| author_role |
author |
| author2 |
Araujo Junior, Edward [UNIFESP] Crott, Gerson Claudio Okido, Marcos Masaru Berezowski, Aderson Tadeu Duarte, Geraldo Marcolin, Alessandra Cristina |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Garcia Almeida, Lissa Fernandes Araujo Junior, Edward [UNIFESP] Crott, Gerson Claudio Okido, Marcos Masaru Berezowski, Aderson Tadeu Duarte, Geraldo Marcolin, Alessandra Cristina |
| dc.subject.por.fl_str_mv |
pregnancy congenital anomaly epidemiological risk factor ultrasound perinatal outcome |
| topic |
pregnancy congenital anomaly epidemiological risk factor ultrasound perinatal outcome |
| description |
Objectives To identify the epidemiological risk factors for congenital anomalies (CAs) and the impact of these fetal malformations on the perinatal outcomes. Methods This prospective cohort study comprised 275 women whose fetuses had CAs. Maternal variables to establish potential risk factors for each group of CA and perinatal outcomes were evaluated. The primary outcome was CA. Secondary outcomes included: fetal growth restriction (FGR) |
| publishDate |
2016 |
| dc.date.none.fl_str_mv |
2016 2020-08-14T13:44:31Z 2020-08-14T13:44:31Z |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1055/s-0036-1586160 Revista Brasileira De Ginecologia E Obstetricia. Rio De Janeiro Rj, v. 38, n. 7, p. 348-355, 2016. 10.1055/s-0036-1586160 WOS000410247300006.pdf 0100-7203 S0100-72032016000700348 https://repositorio.unifesp.br/handle/11600/57712 WOS:000410247300006 |
| dc.identifier.dark.fl_str_mv |
ark:/48912/001300000qf0n |
| url |
http://dx.doi.org/10.1055/s-0036-1586160 https://repositorio.unifesp.br/handle/11600/57712 |
| identifier_str_mv |
Revista Brasileira De Ginecologia E Obstetricia. Rio De Janeiro Rj, v. 38, n. 7, p. 348-355, 2016. 10.1055/s-0036-1586160 WOS000410247300006.pdf 0100-7203 S0100-72032016000700348 WOS:000410247300006 ark:/48912/001300000qf0n |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Revista Brasileira De Ginecologia E Obstetricia |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
348-355 application/pdf |
| dc.coverage.none.fl_str_mv |
Rio De Janeiro Rj |
| dc.publisher.none.fl_str_mv |
Federacao Brasileira Soc Ginecologia & Obstetricia-Febrasgo |
| publisher.none.fl_str_mv |
Federacao Brasileira Soc Ginecologia & Obstetricia-Febrasgo |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
| instname_str |
Universidade Federal de São Paulo (UNIFESP) |
| instacron_str |
UNIFESP |
| institution |
UNIFESP |
| reponame_str |
Repositório Institucional da UNIFESP |
| collection |
Repositório Institucional da UNIFESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
| repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
| _version_ |
1822183931003273216 |
| dc.identifier.doi.none.fl_str_mv |
10.1055/s-0036-1586160 |