Correção de estrabismo paralítico por injeção de toxina botulínica

Detalhes bibliográficos
Autor(a) principal: Wattiez, Raquel [UNIFESP]
Data de Publicação: 2000
Outros Autores: Casanova, Fábio Henrique Cacho [UNIFESP], Cunha, Rosana Nogueira Pires da [UNIFESP], Mendonça, Tomás Scalamandré [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
dARK ID: ark:/48912/001300000vhgq
Texto Completo: http://dx.doi.org/10.1590/S0004-27492000000100014
http://repositorio.unifesp.br/handle/11600/917
Resumo: Purpose: To evaluate the treatment by injection of botulinum toxin in acquired sixth and third nerve palsies. Methods: Fifteen patients were treated with botulinum toxin. They were studied prospectively during nine months, between August, 1998 and May, 1999. In addition to the strabismus examination, a complete ophthalmological evaluation was performed. The patients were followed for 2 to 7 months after the last injection or surgical procedure. Results: Eleven patients (73%) presented with sixth nerve palsy and four (27%) with third nerve palsy. Six cases were acute (40%) and 9 cases (60%) were chronic. Five acute cases (83%) obtained ocular alignment and controlled the deviation with toxin. Two of nine chronic cases (22%) obtained orthotropia after the last injection. Seven chronic cases were treated with toxin and surgery; 4 of these (46%) obtained acceptable ocular aligment and the remaining three cases (32%) did not obtain ocular aligment with this treatment. Conclusion: The toxin was the best treatment for the cases that had residual muscle function and good potential for fusion after sixth and third nerve palsies, because it controlled the deviation and then fusion was obtained without surgery.
id UFSP_6ed988f08b08f86113231a9705d0c350
oai_identifier_str oai:repositorio.unifesp.br/:11600/917
network_acronym_str UFSP
network_name_str Repositório Institucional da UNIFESP
repository_id_str 3465
spelling Correção de estrabismo paralítico por injeção de toxina botulínicaManagement of paralytic strabismus by injection of botulinum toxinBotulinum toxinAcquired paralytic strabismusToxina botulínicaEstrabismo paralítico adquiridoPurpose: To evaluate the treatment by injection of botulinum toxin in acquired sixth and third nerve palsies. Methods: Fifteen patients were treated with botulinum toxin. They were studied prospectively during nine months, between August, 1998 and May, 1999. In addition to the strabismus examination, a complete ophthalmological evaluation was performed. The patients were followed for 2 to 7 months after the last injection or surgical procedure. Results: Eleven patients (73%) presented with sixth nerve palsy and four (27%) with third nerve palsy. Six cases were acute (40%) and 9 cases (60%) were chronic. Five acute cases (83%) obtained ocular alignment and controlled the deviation with toxin. Two of nine chronic cases (22%) obtained orthotropia after the last injection. Seven chronic cases were treated with toxin and surgery; 4 of these (46%) obtained acceptable ocular aligment and the remaining three cases (32%) did not obtain ocular aligment with this treatment. Conclusion: The toxin was the best treatment for the cases that had residual muscle function and good potential for fusion after sixth and third nerve palsies, because it controlled the deviation and then fusion was obtained without surgery.Objetivo: Avaliar a ação da toxina botulínica em paralisias adquiridas de VI e III nervos. Pacientes e métodos: Foram tratados com toxina botulínica 15 pacientes, com diagnóstico de paralisia de VI e III nervos, aguda ou crônica. Foram estudados de forma prospectiva, durante os meses de agosto de 1998 a maio de 1999. O estudo incluiu, além da avaliação do estrabismo, avaliação oftalmológica completa. Os pacientes foram acompanhados por um período de 2 a 7 meses após a última aplicação. Resultados: Onze pacientes (73%) apresentaram paralisias do VI nervo e 4 pacientes (27%), paralisias de III nervo. Seis casos foram agudos (40%) e 9 casos (60%), crônicos. Cinco dos 6 casos agudos (83%) conseguiram controlar o desvio com a toxina botulínica como único tratamento e obter fusão. Dos 9 casos crônicos, 2 casos (22%) corrigiram o desvio só com a toxina, os outros 7, além da aplicação, foram submetidos à cirurgia, dos quais 4 casos (46%) foram corrigidos e os outros 3 casos (32%) não. Conclusão: Concluímos que nos casos em que houve força muscular residual, após a paralisia, e bom potencial de fusão, a toxina botulínica foi o melhor tratamento, pois foi possível controlar o desvio e obter fusão, sem cirurgia.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de OftalmologiaUNIFESP Departamento de OftalmologiaUNIFESP Departamento de Oftalmologia Setor de EstrabismoUNIFESP-EPM Departamento de OftalmologiaUNIFESP, EPM, Depto. de OftalmologiaUNIFESP, Depto. de OftalmologiaUNIFESP, Depto. de Oftalmologia Setor de EstrabismoUNIFESP, EPM Depto. de OftalmologiaSciELOConselho Brasileiro de OftalmologiaUniversidade Federal de São Paulo (UNIFESP)Wattiez, Raquel [UNIFESP]Casanova, Fábio Henrique Cacho [UNIFESP]Cunha, Rosana Nogueira Pires da [UNIFESP]Mendonça, Tomás Scalamandré [UNIFESP]2015-06-14T13:25:00Z2015-06-14T13:25:00Z2000-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion71-77application/pdfhttp://dx.doi.org/10.1590/S0004-27492000000100014Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 63, n. 1, p. 71-77, 2000.10.1590/S0004-27492000000100014S0004-27492000000100014.pdf0004-2749S0004-27492000000100014http://repositorio.unifesp.br/handle/11600/917ark:/48912/001300000vhgqporArquivos Brasileiros de Oftalmologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T04:34:41Zoai:repositorio.unifesp.br/:11600/917Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T20:39:30.907803Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Correção de estrabismo paralítico por injeção de toxina botulínica
Management of paralytic strabismus by injection of botulinum toxin
title Correção de estrabismo paralítico por injeção de toxina botulínica
spellingShingle Correção de estrabismo paralítico por injeção de toxina botulínica
Wattiez, Raquel [UNIFESP]
Botulinum toxin
Acquired paralytic strabismus
Toxina botulínica
Estrabismo paralítico adquirido
title_short Correção de estrabismo paralítico por injeção de toxina botulínica
title_full Correção de estrabismo paralítico por injeção de toxina botulínica
title_fullStr Correção de estrabismo paralítico por injeção de toxina botulínica
title_full_unstemmed Correção de estrabismo paralítico por injeção de toxina botulínica
title_sort Correção de estrabismo paralítico por injeção de toxina botulínica
author Wattiez, Raquel [UNIFESP]
author_facet Wattiez, Raquel [UNIFESP]
Casanova, Fábio Henrique Cacho [UNIFESP]
Cunha, Rosana Nogueira Pires da [UNIFESP]
Mendonça, Tomás Scalamandré [UNIFESP]
author_role author
author2 Casanova, Fábio Henrique Cacho [UNIFESP]
Cunha, Rosana Nogueira Pires da [UNIFESP]
Mendonça, Tomás Scalamandré [UNIFESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Wattiez, Raquel [UNIFESP]
Casanova, Fábio Henrique Cacho [UNIFESP]
Cunha, Rosana Nogueira Pires da [UNIFESP]
Mendonça, Tomás Scalamandré [UNIFESP]
dc.subject.por.fl_str_mv Botulinum toxin
Acquired paralytic strabismus
Toxina botulínica
Estrabismo paralítico adquirido
topic Botulinum toxin
Acquired paralytic strabismus
Toxina botulínica
Estrabismo paralítico adquirido
description Purpose: To evaluate the treatment by injection of botulinum toxin in acquired sixth and third nerve palsies. Methods: Fifteen patients were treated with botulinum toxin. They were studied prospectively during nine months, between August, 1998 and May, 1999. In addition to the strabismus examination, a complete ophthalmological evaluation was performed. The patients were followed for 2 to 7 months after the last injection or surgical procedure. Results: Eleven patients (73%) presented with sixth nerve palsy and four (27%) with third nerve palsy. Six cases were acute (40%) and 9 cases (60%) were chronic. Five acute cases (83%) obtained ocular alignment and controlled the deviation with toxin. Two of nine chronic cases (22%) obtained orthotropia after the last injection. Seven chronic cases were treated with toxin and surgery; 4 of these (46%) obtained acceptable ocular aligment and the remaining three cases (32%) did not obtain ocular aligment with this treatment. Conclusion: The toxin was the best treatment for the cases that had residual muscle function and good potential for fusion after sixth and third nerve palsies, because it controlled the deviation and then fusion was obtained without surgery.
publishDate 2000
dc.date.none.fl_str_mv 2000-02-01
2015-06-14T13:25:00Z
2015-06-14T13:25:00Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0004-27492000000100014
Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 63, n. 1, p. 71-77, 2000.
10.1590/S0004-27492000000100014
S0004-27492000000100014.pdf
0004-2749
S0004-27492000000100014
http://repositorio.unifesp.br/handle/11600/917
dc.identifier.dark.fl_str_mv ark:/48912/001300000vhgq
url http://dx.doi.org/10.1590/S0004-27492000000100014
http://repositorio.unifesp.br/handle/11600/917
identifier_str_mv Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 63, n. 1, p. 71-77, 2000.
10.1590/S0004-27492000000100014
S0004-27492000000100014.pdf
0004-2749
S0004-27492000000100014
ark:/48912/001300000vhgq
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Arquivos Brasileiros de Oftalmologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 71-77
application/pdf
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1818602523155496960