Avaliação do comprometimento da pele no câncer de mama: ultrassonografia pré-operatória e correlação anatomopatológica

• Autor(a) principal: Brandão, Rodrigo Gregório [UNIFESP]
• Data de Publicação: 2016
• Tipo de documento: Dissertação
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=3636524; https://repositorio.unifesp.br/handle/11600/46355
• topic: Breast cancer; Skin; Breast ultrasound; Pathology; Câncer de mama; Pele; Ultrassonografia mamária; Patologia

Introduction: The removal of the overlying skin carcinoma is often unnecessary and can compromise the aesthetic result of breast surgery. In the presence of a tumor, the distance between the lesion and epidermis is given relevance in deciding between preserving or resection of skin overlying the cancer, in conservative surgery such as mastectomy. Objectives: To correlate the tumorskin distance obtained in ultrasound and pathological examinations and to establish a relationship between these parameters. Methods: This was a prospective study conducted on 39 women presenting 41 breast tumors who were diagnosed with invasive cancer and were candidates for conservative or radical surgery. Distance measurements between the tumor and skin were performed using preoperative ultrasound examinations and an anatomopathological specimen. Results: The mean distance between the tumour and skin obtained from the ultrasound examinations was 0.8 cm, with a minimum of 0.15 cm and a maximum of 2.43 cm. In the pathological examinations, the mean was 2.21 cm, with values ranging between 0.5 and 5.0 cm. The Pearson correlation between the methods was r = 0.75. Conclusion: The tumour-skin measurements observed during ultrasound examinations were well correlated with those observed during pathological examinations. The distance between the tumor and skin of the breast obtained by sonography is always lower than that obtained in pathology specimen, on average 3.1 times smaller. The intraobserver and interobserver variability in achieving tumor-skin distance through ultrasound and pathology analysis was not significant. The anatomopathological distance between tumor and skin can be estimated by the model: Dpathology = 0.69 + 1.89 x Dultrasound, where D is distance. Breast cancer. Skin. Breast ultrasound. Pathology.