Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/8423 http://dx.doi.org/10.1590/rbeb.2014.013 |
Resumo: | INTRODUCTION: The rupture of atherosclerotic plaques causes millions of death yearly. It is known that the kind of predominant tissue is associated with its dangerousness. In addition, the mechanical properties of plaques have been proved to be a good parameter to characterize the type of tissue, important information for therapeutic decisions. METHODS: Therefore, we present an alternative and simple way to discriminate tissues. The procedure relies on computing an index, the ratio of the plaque area variation of a suspecting plaque, using images acquired with vessel and plaques, pre and post-deformation, under different intraluminal pressure. Numerical phantoms of coronary cross-sections with different morphological aspects, and simulated with a range of properties, were used for evaluation. RESULTS: The outcomes provided by this index and a widely used one were compared, so as to measure their correspondence. As a result, correlations up to 99%, a strong agreement with Bland-Altman and very similar histograms between the two indices, have shown a good level of equivalence between the methods. CONCLUSION: The results demonstrated that the proposed index discriminates highly lipidic from fibro-lipidic and calcified tissues in many situations, as good as the widely used index, yet the proposed method is much simpler to be computed. |
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Moraes, Matheus Cardoso [UNIFESP]Cardoso, Fernando MitsuyamaFuruie, Sérgio ShiguemiUniversidade Federal de São Paulo (UNIFESP)Universidade de São Paulo (USP)2015-06-14T13:47:08Z2015-06-14T13:47:08Z2014-06-01Revista Brasileira de Engenharia Biomédica. SBEB - Sociedade Brasileira de Engenharia Biomédica, v. 30, n. 2, p. 159-172, 2014.1517-3151http://repositorio.unifesp.br/handle/11600/8423http://dx.doi.org/10.1590/rbeb.2014.013S1517-31512014000200008.pdfS1517-3151201400020000810.1590/rbeb.2014.013INTRODUCTION: The rupture of atherosclerotic plaques causes millions of death yearly. It is known that the kind of predominant tissue is associated with its dangerousness. In addition, the mechanical properties of plaques have been proved to be a good parameter to characterize the type of tissue, important information for therapeutic decisions. METHODS: Therefore, we present an alternative and simple way to discriminate tissues. The procedure relies on computing an index, the ratio of the plaque area variation of a suspecting plaque, using images acquired with vessel and plaques, pre and post-deformation, under different intraluminal pressure. Numerical phantoms of coronary cross-sections with different morphological aspects, and simulated with a range of properties, were used for evaluation. RESULTS: The outcomes provided by this index and a widely used one were compared, so as to measure their correspondence. As a result, correlations up to 99%, a strong agreement with Bland-Altman and very similar histograms between the two indices, have shown a good level of equivalence between the methods. CONCLUSION: The results demonstrated that the proposed index discriminates highly lipidic from fibro-lipidic and calcified tissues in many situations, as good as the widely used index, yet the proposed method is much simpler to be computed.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Federal de São Paulo (UNIFESP) Instituto de Ciência e Tecnologia Departamento de Ciência e TecnologiaUniversidade de São Paulo Escola Politécnica Departamento de Engenharia de Telecomunicações e ControleUNIFESP, Instituto de Ciência e Tecnologia Depto. de Ciência e TecnologiaSciELO159-172engSBEB - Sociedade Brasileira de Engenharia BiomédicaRevista Brasileira de Engenharia BiomédicaIntravascular Ultrasound (IVUS)AtherosclerosisIntravascular elastographyPhantomsStrain mapAtherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1517-31512014000200008.pdfapplication/pdf7482276${dspace.ui.url}/bitstream/11600/8423/1/S1517-31512014000200008.pdfda1bd5cc0c3a0da66aa1b4b4eaea117cMD51open accessTEXTS1517-31512014000200008.pdf.txtS1517-31512014000200008.pdf.txtExtracted texttext/plain46148${dspace.ui.url}/bitstream/11600/8423/9/S1517-31512014000200008.pdf.txtdd07c390ebe11d1845de285062d7b050MD59open accessTHUMBNAILS1517-31512014000200008.pdf.jpgS1517-31512014000200008.pdf.jpgIM Thumbnailimage/jpeg6897${dspace.ui.url}/bitstream/11600/8423/11/S1517-31512014000200008.pdf.jpgd4a618b5b6df7909c90a1670a457f352MD511open access11600/84232023-06-05 19:09:09.395open accessoai:repositorio.unifesp.br:11600/8423Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-06-05T22:09:09Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation |
title |
Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation |
spellingShingle |
Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation Moraes, Matheus Cardoso [UNIFESP] Intravascular Ultrasound (IVUS) Atherosclerosis Intravascular elastography Phantoms Strain map |
title_short |
Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation |
title_full |
Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation |
title_fullStr |
Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation |
title_full_unstemmed |
Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation |
title_sort |
Atherosclerotic plaque characterization using plaque area variation in IVUS images during compression: a computational investigation |
author |
Moraes, Matheus Cardoso [UNIFESP] |
author_facet |
Moraes, Matheus Cardoso [UNIFESP] Cardoso, Fernando Mitsuyama Furuie, Sérgio Shiguemi |
author_role |
author |
author2 |
Cardoso, Fernando Mitsuyama Furuie, Sérgio Shiguemi |
author2_role |
author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Moraes, Matheus Cardoso [UNIFESP] Cardoso, Fernando Mitsuyama Furuie, Sérgio Shiguemi |
dc.subject.eng.fl_str_mv |
Intravascular Ultrasound (IVUS) Atherosclerosis Intravascular elastography Phantoms Strain map |
topic |
Intravascular Ultrasound (IVUS) Atherosclerosis Intravascular elastography Phantoms Strain map |
description |
INTRODUCTION: The rupture of atherosclerotic plaques causes millions of death yearly. It is known that the kind of predominant tissue is associated with its dangerousness. In addition, the mechanical properties of plaques have been proved to be a good parameter to characterize the type of tissue, important information for therapeutic decisions. METHODS: Therefore, we present an alternative and simple way to discriminate tissues. The procedure relies on computing an index, the ratio of the plaque area variation of a suspecting plaque, using images acquired with vessel and plaques, pre and post-deformation, under different intraluminal pressure. Numerical phantoms of coronary cross-sections with different morphological aspects, and simulated with a range of properties, were used for evaluation. RESULTS: The outcomes provided by this index and a widely used one were compared, so as to measure their correspondence. As a result, correlations up to 99%, a strong agreement with Bland-Altman and very similar histograms between the two indices, have shown a good level of equivalence between the methods. CONCLUSION: The results demonstrated that the proposed index discriminates highly lipidic from fibro-lipidic and calcified tissues in many situations, as good as the widely used index, yet the proposed method is much simpler to be computed. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014-06-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:47:08Z |
dc.date.available.fl_str_mv |
2015-06-14T13:47:08Z |
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info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
dc.identifier.citation.fl_str_mv |
Revista Brasileira de Engenharia Biomédica. SBEB - Sociedade Brasileira de Engenharia Biomédica, v. 30, n. 2, p. 159-172, 2014. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/8423 http://dx.doi.org/10.1590/rbeb.2014.013 |
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1517-3151 |
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S1517-31512014000200008.pdf |
dc.identifier.scielo.none.fl_str_mv |
S1517-31512014000200008 |
dc.identifier.doi.none.fl_str_mv |
10.1590/rbeb.2014.013 |
identifier_str_mv |
Revista Brasileira de Engenharia Biomédica. SBEB - Sociedade Brasileira de Engenharia Biomédica, v. 30, n. 2, p. 159-172, 2014. 1517-3151 S1517-31512014000200008.pdf S1517-31512014000200008 10.1590/rbeb.2014.013 |
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http://repositorio.unifesp.br/handle/11600/8423 http://dx.doi.org/10.1590/rbeb.2014.013 |
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SBEB - Sociedade Brasileira de Engenharia Biomédica |
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SBEB - Sociedade Brasileira de Engenharia Biomédica |
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