Avaliação da concentração das fibras do tecido conjuntivo quando da associação de poliglactina 910 e silicone: estudo experimental em ratos

• Autor(a) principal: Vivi, Ayder Anselmo Gomes [UNIFESP]
• Data de Publicação: 1997
• Outros Autores: Ortiz, Valdemar [UNIFESP], Oliani, Sonia Maria [UNIFESP], Gomes, Paulo de Oliveira [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• dARK ID: ark:/48912/001300000z36c
• Texto Completo: http://dx.doi.org/10.1590/S0102-86501997000300011; http://repositorio.unifesp.br/handle/11600/529
• topic: Silicones; Polyglactin 910; Collagen; Connective Tissue; Silicones; Poliglactina 910; Colágeno; Tecido Conjuntivo

It is an important area of investigation the choice of an adequate substance for the fixation of silicon prosthesis without generating a lot of fibrotic tissue reaction. We have studied the tissue reaction after the implantation of silicon prosthesis with polyglactin 910 threads. Silicon grids measuring 1,5 x 1,5cm and thickness of 0,7mm were implanted under the subcutaneous tissue of rats. The animals were studied 30, 60 and 90 days after implantation. Then they were sacrificed. The grids and the adjacent tissue were excised. The time did not interfere with the number of colagen fibers in sub-groups. Quantity of colagen fibers were not different amoung the sub-groups of 30, 60 and 90 days. With or without poliglactin 910. In the group of pure silicon grids we have found a significant difference among the reticular fibers. The great number was observed in the 30 and 60 days groups if compared with the group of 90 days. The polyglactin 910 with the silicon grid not change the amount of connective tissue fibers in the grid¢s fenestrations.