Demyelinating disease in patients with myasthenia gravis

Detalhes bibliográficos
Autor(a) principal: Bichuetti, Denis Bernardi [UNIFESP]
Data de Publicação: 2008
Outros Autores: Barros, Tatiane Martins de [UNIFESP], Oliveira, Enedina Maria Lobato de [UNIFESP], Annes, Marcelo [UNIFESP], Gabbai, Alberto Alain [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0004-282X2008000100002
http://repositorio.unifesp.br/handle/11600/4259
Resumo: Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinating diseases, two monophasic and one recurrent neuromyelitis optica, several years after the diagnosis of MG, and discuss their clinical courses.
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spelling Demyelinating disease in patients with myasthenia gravisDoenças desmielinizantes em pacientes com miastenia gravismyasthenia gravismyelinating diseaseassociationmiastenia gravisdoenças desmielinizanteassociaçãoMyasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinating diseases, two monophasic and one recurrent neuromyelitis optica, several years after the diagnosis of MG, and discuss their clinical courses.Miastenia gravis (MG) é doença autoimune caracterizada por episódios de fraqueza muscular alternados com melhora, causada por bloqueio da junção neuromuscular. Pacientes com MG podem apresentar outras doenças autoimunes, comumente hipo ou hipertiroidismo, e a associação de MG com doenças desmielinizantes é raramente descrita. Relatamos três pacientes brasileiros com MG que desenvolveram doenças desmielinizantes, dois monofásicos e um neuromielite óptica recorrente, vários anos após o diagnóstico de MG e discutimos seus cursos clínicos.Federal University of São Paulo Neurology and Neurosurgery DepartmentFederal University of São PauloBayer Schering Pharma do BrasilUNIFESP, Neurology and Neurosurgery DepartmentUNIFESPSciELOAcademia Brasileira de Neurologia - ABNEUROUniversidade Federal de São Paulo (UNIFESP)Bayer Schering Pharma do BrasilBichuetti, Denis Bernardi [UNIFESP]Barros, Tatiane Martins de [UNIFESP]Oliveira, Enedina Maria Lobato de [UNIFESP]Annes, Marcelo [UNIFESP]Gabbai, Alberto Alain [UNIFESP]2015-06-14T13:38:25Z2015-06-14T13:38:25Z2008-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion5-7application/pdfhttp://dx.doi.org/10.1590/S0004-282X2008000100002Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 66, n. 1, p. 5-7, 2008.10.1590/S0004-282X2008000100002S0004-282X2008000100002.pdf0004-282XS0004-282X2008000100002http://repositorio.unifesp.br/handle/11600/4259engArquivos de Neuro-Psiquiatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-04T18:31:26Zoai:repositorio.unifesp.br/:11600/4259Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-04T18:31:26Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Demyelinating disease in patients with myasthenia gravis
Doenças desmielinizantes em pacientes com miastenia gravis
title Demyelinating disease in patients with myasthenia gravis
spellingShingle Demyelinating disease in patients with myasthenia gravis
Bichuetti, Denis Bernardi [UNIFESP]
myasthenia gravis
myelinating disease
association
miastenia gravis
doenças desmielinizante
associação
title_short Demyelinating disease in patients with myasthenia gravis
title_full Demyelinating disease in patients with myasthenia gravis
title_fullStr Demyelinating disease in patients with myasthenia gravis
title_full_unstemmed Demyelinating disease in patients with myasthenia gravis
title_sort Demyelinating disease in patients with myasthenia gravis
author Bichuetti, Denis Bernardi [UNIFESP]
author_facet Bichuetti, Denis Bernardi [UNIFESP]
Barros, Tatiane Martins de [UNIFESP]
Oliveira, Enedina Maria Lobato de [UNIFESP]
Annes, Marcelo [UNIFESP]
Gabbai, Alberto Alain [UNIFESP]
author_role author
author2 Barros, Tatiane Martins de [UNIFESP]
Oliveira, Enedina Maria Lobato de [UNIFESP]
Annes, Marcelo [UNIFESP]
Gabbai, Alberto Alain [UNIFESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Bayer Schering Pharma do Brasil
dc.contributor.author.fl_str_mv Bichuetti, Denis Bernardi [UNIFESP]
Barros, Tatiane Martins de [UNIFESP]
Oliveira, Enedina Maria Lobato de [UNIFESP]
Annes, Marcelo [UNIFESP]
Gabbai, Alberto Alain [UNIFESP]
dc.subject.por.fl_str_mv myasthenia gravis
myelinating disease
association
miastenia gravis
doenças desmielinizante
associação
topic myasthenia gravis
myelinating disease
association
miastenia gravis
doenças desmielinizante
associação
description Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinating diseases, two monophasic and one recurrent neuromyelitis optica, several years after the diagnosis of MG, and discuss their clinical courses.
publishDate 2008
dc.date.none.fl_str_mv 2008-03-01
2015-06-14T13:38:25Z
2015-06-14T13:38:25Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0004-282X2008000100002
Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 66, n. 1, p. 5-7, 2008.
10.1590/S0004-282X2008000100002
S0004-282X2008000100002.pdf
0004-282X
S0004-282X2008000100002
http://repositorio.unifesp.br/handle/11600/4259
url http://dx.doi.org/10.1590/S0004-282X2008000100002
http://repositorio.unifesp.br/handle/11600/4259
identifier_str_mv Arquivos de Neuro-Psiquiatria. Academia Brasileira de Neurologia - ABNEURO, v. 66, n. 1, p. 5-7, 2008.
10.1590/S0004-282X2008000100002
S0004-282X2008000100002.pdf
0004-282X
S0004-282X2008000100002
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos de Neuro-Psiquiatria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 5-7
application/pdf
dc.publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
publisher.none.fl_str_mv Academia Brasileira de Neurologia - ABNEURO
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268352478052352

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