An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa

Detalhes bibliográficos
Autor(a) principal: Abe, Cecilia Mari [UNIFESP]
Data de Publicação: 2001
Outros Autores: Knutton, Stuart, Pedroso, Margareth Z. [UNIFESP], Freymuller, Edna [UNIFESP], Gomes, Tania Aparecida Tardelli [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.x
http://repositorio.unifesp.br/handle/11600/26628
Resumo: The pathogenic mechanisms of enteroaggregative Escherichia coh (EAEC) are not well defined. We investigated the interaction of EAEC strain 236 (serotype O111:H12) with polarised Caco-2 and T84 human intestinal epithelia] cells lines, and,vith human jejunal and colonic mucosa. Strain 236 adhered to both polarised cell lines and to both intestinal tissue types, but caused severe damage and was invasive only in T84 cells and colonic mucosa. in contrast, prototype EAEC strain 042, which also adhered to the Cultured intestinal cell lines, did not adhere to or invade jejunal or colonic tissue. These observations suggest a heterogeneity of virulence properties within the EAEC category of diarrhoea-causing E. coli. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science BN. All rights reserved.
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spelling An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosaenteroaggregativeEscherichia coliinvasionvirulence propertiesadherenceThe pathogenic mechanisms of enteroaggregative Escherichia coh (EAEC) are not well defined. We investigated the interaction of EAEC strain 236 (serotype O111:H12) with polarised Caco-2 and T84 human intestinal epithelia] cells lines, and,vith human jejunal and colonic mucosa. Strain 236 adhered to both polarised cell lines and to both intestinal tissue types, but caused severe damage and was invasive only in T84 cells and colonic mucosa. in contrast, prototype EAEC strain 042, which also adhered to the Cultured intestinal cell lines, did not adhere to or invade jejunal or colonic tissue. These observations suggest a heterogeneity of virulence properties within the EAEC category of diarrhoea-causing E. coli. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science BN. All rights reserved.Universidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, BrazilUniv Birmingham, Inst Child Hlth, Birmingham B4 6NH, W Midlands, EnglandUniversidade Federal de São Paulo, Escola Paulista Med, Ctr Microscopia Eletron, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Ctr Microscopia Eletron, BR-04023062 São Paulo, BrazilWeb of ScienceElsevier B.V.Universidade Federal de São Paulo (UNIFESP)Univ BirminghamAbe, Cecilia Mari [UNIFESP]Knutton, StuartPedroso, Margareth Z. [UNIFESP]Freymuller, Edna [UNIFESP]Gomes, Tania Aparecida Tardelli [UNIFESP]2016-01-24T12:31:29Z2016-01-24T12:31:29Z2001-09-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion199-205http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.xFems Microbiology Letters. Amsterdam: Elsevier B.V., v. 203, n. 2, p. 199-205, 2001.10.1111/j.1574-6968.2001.tb10841.x0378-1097http://repositorio.unifesp.br/handle/11600/26628WOS:000171422500011engFems Microbiology Lettersinfo:eu-repo/semantics/openAccesshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2016-02-03T15:18:54Zoai:repositorio.unifesp.br/:11600/26628Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652016-02-03T15:18:54Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
title An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
spellingShingle An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
Abe, Cecilia Mari [UNIFESP]
enteroaggregative
Escherichia coli
invasion
virulence properties
adherence
title_short An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
title_full An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
title_fullStr An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
title_full_unstemmed An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
title_sort An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
author Abe, Cecilia Mari [UNIFESP]
author_facet Abe, Cecilia Mari [UNIFESP]
Knutton, Stuart
Pedroso, Margareth Z. [UNIFESP]
Freymuller, Edna [UNIFESP]
Gomes, Tania Aparecida Tardelli [UNIFESP]
author_role author
author2 Knutton, Stuart
Pedroso, Margareth Z. [UNIFESP]
Freymuller, Edna [UNIFESP]
Gomes, Tania Aparecida Tardelli [UNIFESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Univ Birmingham
dc.contributor.author.fl_str_mv Abe, Cecilia Mari [UNIFESP]
Knutton, Stuart
Pedroso, Margareth Z. [UNIFESP]
Freymuller, Edna [UNIFESP]
Gomes, Tania Aparecida Tardelli [UNIFESP]
dc.subject.por.fl_str_mv enteroaggregative
Escherichia coli
invasion
virulence properties
adherence
topic enteroaggregative
Escherichia coli
invasion
virulence properties
adherence
description The pathogenic mechanisms of enteroaggregative Escherichia coh (EAEC) are not well defined. We investigated the interaction of EAEC strain 236 (serotype O111:H12) with polarised Caco-2 and T84 human intestinal epithelia] cells lines, and,vith human jejunal and colonic mucosa. Strain 236 adhered to both polarised cell lines and to both intestinal tissue types, but caused severe damage and was invasive only in T84 cells and colonic mucosa. in contrast, prototype EAEC strain 042, which also adhered to the Cultured intestinal cell lines, did not adhere to or invade jejunal or colonic tissue. These observations suggest a heterogeneity of virulence properties within the EAEC category of diarrhoea-causing E. coli. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science BN. All rights reserved.
publishDate 2001
dc.date.none.fl_str_mv 2001-09-25
2016-01-24T12:31:29Z
2016-01-24T12:31:29Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.x
Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 203, n. 2, p. 199-205, 2001.
10.1111/j.1574-6968.2001.tb10841.x
0378-1097
http://repositorio.unifesp.br/handle/11600/26628
WOS:000171422500011
url http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.x
http://repositorio.unifesp.br/handle/11600/26628
identifier_str_mv Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 203, n. 2, p. 199-205, 2001.
10.1111/j.1574-6968.2001.tb10841.x
0378-1097
WOS:000171422500011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Fems Microbiology Letters
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
eu_rights_str_mv openAccess
rights_invalid_str_mv http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
dc.format.none.fl_str_mv 199-205
dc.publisher.none.fl_str_mv Elsevier B.V.
publisher.none.fl_str_mv Elsevier B.V.
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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