An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa
Autor(a) principal: | |
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Data de Publicação: | 2001 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.x http://repositorio.unifesp.br/handle/11600/26628 |
Resumo: | The pathogenic mechanisms of enteroaggregative Escherichia coh (EAEC) are not well defined. We investigated the interaction of EAEC strain 236 (serotype O111:H12) with polarised Caco-2 and T84 human intestinal epithelia] cells lines, and,vith human jejunal and colonic mucosa. Strain 236 adhered to both polarised cell lines and to both intestinal tissue types, but caused severe damage and was invasive only in T84 cells and colonic mucosa. in contrast, prototype EAEC strain 042, which also adhered to the Cultured intestinal cell lines, did not adhere to or invade jejunal or colonic tissue. These observations suggest a heterogeneity of virulence properties within the EAEC category of diarrhoea-causing E. coli. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science BN. All rights reserved. |
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An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosaenteroaggregativeEscherichia coliinvasionvirulence propertiesadherenceThe pathogenic mechanisms of enteroaggregative Escherichia coh (EAEC) are not well defined. We investigated the interaction of EAEC strain 236 (serotype O111:H12) with polarised Caco-2 and T84 human intestinal epithelia] cells lines, and,vith human jejunal and colonic mucosa. Strain 236 adhered to both polarised cell lines and to both intestinal tissue types, but caused severe damage and was invasive only in T84 cells and colonic mucosa. in contrast, prototype EAEC strain 042, which also adhered to the Cultured intestinal cell lines, did not adhere to or invade jejunal or colonic tissue. These observations suggest a heterogeneity of virulence properties within the EAEC category of diarrhoea-causing E. coli. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science BN. All rights reserved.Universidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, BrazilUniv Birmingham, Inst Child Hlth, Birmingham B4 6NH, W Midlands, EnglandUniversidade Federal de São Paulo, Escola Paulista Med, Ctr Microscopia Eletron, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Ctr Microscopia Eletron, BR-04023062 São Paulo, BrazilWeb of ScienceElsevier B.V.Universidade Federal de São Paulo (UNIFESP)Univ BirminghamAbe, Cecilia Mari [UNIFESP]Knutton, StuartPedroso, Margareth Z. [UNIFESP]Freymuller, Edna [UNIFESP]Gomes, Tania Aparecida Tardelli [UNIFESP]2016-01-24T12:31:29Z2016-01-24T12:31:29Z2001-09-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion199-205http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.xFems Microbiology Letters. Amsterdam: Elsevier B.V., v. 203, n. 2, p. 199-205, 2001.10.1111/j.1574-6968.2001.tb10841.x0378-1097http://repositorio.unifesp.br/handle/11600/26628WOS:000171422500011engFems Microbiology Lettersinfo:eu-repo/semantics/openAccesshttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policyreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2016-02-03T15:18:54Zoai:repositorio.unifesp.br/:11600/26628Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652016-02-03T15:18:54Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa |
title |
An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa |
spellingShingle |
An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa Abe, Cecilia Mari [UNIFESP] enteroaggregative Escherichia coli invasion virulence properties adherence |
title_short |
An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa |
title_full |
An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa |
title_fullStr |
An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa |
title_full_unstemmed |
An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa |
title_sort |
An enteroaggregative Escherichia coli strain of serotype O111 : H12 damages and invades cultured T84 cells and human colonic mucosa |
author |
Abe, Cecilia Mari [UNIFESP] |
author_facet |
Abe, Cecilia Mari [UNIFESP] Knutton, Stuart Pedroso, Margareth Z. [UNIFESP] Freymuller, Edna [UNIFESP] Gomes, Tania Aparecida Tardelli [UNIFESP] |
author_role |
author |
author2 |
Knutton, Stuart Pedroso, Margareth Z. [UNIFESP] Freymuller, Edna [UNIFESP] Gomes, Tania Aparecida Tardelli [UNIFESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Univ Birmingham |
dc.contributor.author.fl_str_mv |
Abe, Cecilia Mari [UNIFESP] Knutton, Stuart Pedroso, Margareth Z. [UNIFESP] Freymuller, Edna [UNIFESP] Gomes, Tania Aparecida Tardelli [UNIFESP] |
dc.subject.por.fl_str_mv |
enteroaggregative Escherichia coli invasion virulence properties adherence |
topic |
enteroaggregative Escherichia coli invasion virulence properties adherence |
description |
The pathogenic mechanisms of enteroaggregative Escherichia coh (EAEC) are not well defined. We investigated the interaction of EAEC strain 236 (serotype O111:H12) with polarised Caco-2 and T84 human intestinal epithelia] cells lines, and,vith human jejunal and colonic mucosa. Strain 236 adhered to both polarised cell lines and to both intestinal tissue types, but caused severe damage and was invasive only in T84 cells and colonic mucosa. in contrast, prototype EAEC strain 042, which also adhered to the Cultured intestinal cell lines, did not adhere to or invade jejunal or colonic tissue. These observations suggest a heterogeneity of virulence properties within the EAEC category of diarrhoea-causing E. coli. (C) 2001 Federation of European Microbiological Societies. Published by Elsevier Science BN. All rights reserved. |
publishDate |
2001 |
dc.date.none.fl_str_mv |
2001-09-25 2016-01-24T12:31:29Z 2016-01-24T12:31:29Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.x Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 203, n. 2, p. 199-205, 2001. 10.1111/j.1574-6968.2001.tb10841.x 0378-1097 http://repositorio.unifesp.br/handle/11600/26628 WOS:000171422500011 |
url |
http://dx.doi.org/10.1111/j.1574-6968.2001.tb10841.x http://repositorio.unifesp.br/handle/11600/26628 |
identifier_str_mv |
Fems Microbiology Letters. Amsterdam: Elsevier B.V., v. 203, n. 2, p. 199-205, 2001. 10.1111/j.1574-6968.2001.tb10841.x 0378-1097 WOS:000171422500011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Fems Microbiology Letters |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy |
dc.format.none.fl_str_mv |
199-205 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268428483035136 |