Análise da modulação autonômica da frequência cardíaca em indivíduos saudáveis expostos à poluição atmosférica por tempo prolongado

• Autor(a) principal: Costa e Oliveira, Juliana Regis da[UNIFESP]
• Data de Publicação: 2019
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7741478; https://repositorio.unifesp.br/handle/11600/59452
• topic: Environmental Pollution; Air Pollution; Cardiovascular System; Autonomic Nervous System; Poluição Ambiental; Poluição Do Ar; Sistema Cardiovascular; Sistema Nervoso Autônomo

Objective. To analyze the autonomic modulation of heart rate in individuals exposed to air pollution for a long time. Method. We analyzed 109 individuals, aged between 18 and 49 years, living in an area contaminated by air pollution, located in the city of Cubatão (SP). The control area corresponded to the municipality of Peruíbe (SP). Intergroups were analyzed (experimental groups: 29 individuals living in the municipality of Cubatão and exposed for less than 15 years and 31 - individuals living in the municipality of Cubatão and exposed for more than 15 years, and 49 individuals in the control group) with linear indexes (frequency domain indexes - LF, HF and LF/HF, time domain - SDNN, Pnn50 and RMSSD, and geometric indexes - SD1, SD2, SD1/SD2, RRTri and TINN) and nonlinear (symbolic analysis and Entropy of Shannon) of VFC. Results. All the linear and geometric indexes of the time domain presented statistical significance, with the exception of the TINN index. There were differences between groups CG and E2, and E1 and E2 in relation to RMSSD (p = 0.033, p = 0.042), Pnn50 (p = 0.030, p = 0.042), SD1 (p = 0.034, p = 0.045) and RRTri (p = 0.016, p = 0.019), respectively. The difference found in the SD1/SD2 (p = 0.024) was observed only between the CG and E2 groups, and in the SDNN (p = 0.035) and SD2 (p = 0.041) only between the E1 and E2 groups. In the frequency domain, only the LFms2 index presented a statistically significant difference. In the post hoc test, differences between groups E2 and E1 (p = 0.041) were observed. Regarding the symbolic analysis and ES, all items appeared with statistical significance, except for the 1V index. In the post hoc analyzes, differences between the CG and E2 groups were found in the variables 0V (p = 0.014), 2LV (p = 0.014) and 2ULV (p = 0.015). The ES variable presented differences between all groups (CG and E1 p = 0.035, GC and E2 p = <0.001, E1 and E2 p = 0.029). Conclusion. It was concluded that the group of individuals exposed to air pollution for a period of more than 15 years presented lower parasympathetic modulation, less global HRV, and greater sympathetic modulation when compared to the control group. And when compared to the group of individuals exposed to air pollution for a period of less than 15 years, less parasympathetic modulation and global HRV occurred.