T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2007 |
| Outros Autores: | , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNIFESP |
| Texto Completo: | http://dx.doi.org/10.1128/CVI.00458-06 http://repositorio.unifesp.br/handle/11600/29610 |
Resumo: | Vaccines with synthetic peptides induce the immune response to epitopes that bind to several RLA alleles. By using a TEPITOPE algorithm, we selected and analyzed the T-cell responses of peripheral blood mononuclear cells from 29 paracoccidioidomycosis (PCM) patients to peptides of the immunodominant gp43 antigen of Paracoccidioides brasiliensis, the causative agent of PCM. |
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T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individualsVaccines with synthetic peptides induce the immune response to epitopes that bind to several RLA alleles. By using a TEPITOPE algorithm, we selected and analyzed the T-cell responses of peripheral blood mononuclear cells from 29 paracoccidioidomycosis (PCM) patients to peptides of the immunodominant gp43 antigen of Paracoccidioides brasiliensis, the causative agent of PCM.Universidade Federal de São Paulo, Disciplina Biol Celular, Dept Microbiol Imunol & Parasitol, BR-04023062 São Paulo, BrazilMillennium Inst, Immunol Lab, Inst Heart, INCOR, São Paulo, BrazilMillennium Inst, Div Clin Immunol & Allergy, São Paulo, BrazilMillennium Inst, Inst Invest Immunol, São Paulo, BrazilUniv São Paulo, Sch Med, Div Infect & Parasit Dis, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Biophys, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, Disciplina Biol Celular, Dept Microbiol Imunol & Parasitol, BR-04023062 São Paulo, BrazilUniversidade Federal de São Paulo, Dept Biophys, BR-04023062 São Paulo, BrazilWeb of ScienceAmer Soc MicrobiologyUniversidade Federal de São Paulo (UNIFESP)Millennium InstUniversidade de São Paulo (USP)Iwai, Leo KeiYoshida, MarciaSadahiro, AyaSilva, Washington Robert daMarin, Maria LuciaGoldberg, Anna CarlaJuliano, Maria AparecidaJuliano, LuizShikanai-Yasuda, Maria AparecidaKalil, JorgeCunha-Neto, EdecioTravassos, Luiz R. [UNIFESP]2016-01-24T12:42:00Z2016-01-24T12:42:00Z2007-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion474-476application/pdfhttp://dx.doi.org/10.1128/CVI.00458-06Clinical and Vaccine Immunology. Washington: Amer Soc Microbiology, v. 14, n. 4, p. 474-476, 2007.10.1128/CVI.00458-06WOS000245863500020.pdf1556-6811http://repositorio.unifesp.br/handle/11600/29610WOS:000245863500020engClinical and Vaccine Immunologyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-07T15:29:08Zoai:repositorio.unifesp.br/:11600/29610Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-07T15:29:08Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
| dc.title.none.fl_str_mv |
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals |
| title |
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals |
| spellingShingle |
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals Iwai, Leo Kei |
| title_short |
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals |
| title_full |
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals |
| title_fullStr |
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals |
| title_full_unstemmed |
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals |
| title_sort |
T-cell recognition of Paracoccidioides brasiliensis gp43-derived peptides in patients with paracoccidioidomycosis and healthy individuals |
| author |
Iwai, Leo Kei |
| author_facet |
Iwai, Leo Kei Yoshida, Marcia Sadahiro, Aya Silva, Washington Robert da Marin, Maria Lucia Goldberg, Anna Carla Juliano, Maria Aparecida Juliano, Luiz Shikanai-Yasuda, Maria Aparecida Kalil, Jorge Cunha-Neto, Edecio Travassos, Luiz R. [UNIFESP] |
| author_role |
author |
| author2 |
Yoshida, Marcia Sadahiro, Aya Silva, Washington Robert da Marin, Maria Lucia Goldberg, Anna Carla Juliano, Maria Aparecida Juliano, Luiz Shikanai-Yasuda, Maria Aparecida Kalil, Jorge Cunha-Neto, Edecio Travassos, Luiz R. [UNIFESP] |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) Millennium Inst Universidade de São Paulo (USP) |
| dc.contributor.author.fl_str_mv |
Iwai, Leo Kei Yoshida, Marcia Sadahiro, Aya Silva, Washington Robert da Marin, Maria Lucia Goldberg, Anna Carla Juliano, Maria Aparecida Juliano, Luiz Shikanai-Yasuda, Maria Aparecida Kalil, Jorge Cunha-Neto, Edecio Travassos, Luiz R. [UNIFESP] |
| description |
Vaccines with synthetic peptides induce the immune response to epitopes that bind to several RLA alleles. By using a TEPITOPE algorithm, we selected and analyzed the T-cell responses of peripheral blood mononuclear cells from 29 paracoccidioidomycosis (PCM) patients to peptides of the immunodominant gp43 antigen of Paracoccidioides brasiliensis, the causative agent of PCM. |
| publishDate |
2007 |
| dc.date.none.fl_str_mv |
2007-04-01 2016-01-24T12:42:00Z 2016-01-24T12:42:00Z |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1128/CVI.00458-06 Clinical and Vaccine Immunology. Washington: Amer Soc Microbiology, v. 14, n. 4, p. 474-476, 2007. 10.1128/CVI.00458-06 WOS000245863500020.pdf 1556-6811 http://repositorio.unifesp.br/handle/11600/29610 WOS:000245863500020 |
| url |
http://dx.doi.org/10.1128/CVI.00458-06 http://repositorio.unifesp.br/handle/11600/29610 |
| identifier_str_mv |
Clinical and Vaccine Immunology. Washington: Amer Soc Microbiology, v. 14, n. 4, p. 474-476, 2007. 10.1128/CVI.00458-06 WOS000245863500020.pdf 1556-6811 WOS:000245863500020 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
Clinical and Vaccine Immunology |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
474-476 application/pdf |
| dc.publisher.none.fl_str_mv |
Amer Soc Microbiology |
| publisher.none.fl_str_mv |
Amer Soc Microbiology |
| dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
| instname_str |
Universidade Federal de São Paulo (UNIFESP) |
| instacron_str |
UNIFESP |
| institution |
UNIFESP |
| reponame_str |
Repositório Institucional da UNIFESP |
| collection |
Repositório Institucional da UNIFESP |
| repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
| repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
| _version_ |
1814268434200920064 |