Working memory assessment in schizophrenia and its correlation with executive functions ability

Detalhes bibliográficos
Autor(a) principal: Berberian, Arthur de Almeida [UNIFESP]
Data de Publicação: 2009
Outros Autores: Trevisan, Bruna Tonietti, Moriyama, Tais Silveira [UNIFESP], Montiel, José Maria, Oliveira, José Ari Carletti de, Seabra, Alessandra Gotuzo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S1516-44462009000300007
http://repositorio.unifesp.br/handle/11600/5198
Resumo: OBJECTIVE: Working memory impairment is common in schizophrenia and is possibly a cause of multiple features of the disorder. However few studies have replicated such findings of impairment patterns in Brazilian samples. The main target of this study was to assess auditory and visual working memory in patients with schizophrenia, to assess if they work as separate systems, and to correlate working memory deficits with executive functions. METHOD: Twenty subjects with schizophrenia and twenty healthy subjects matched by gender, age, and schooling have participated. The abilities assessed were auditory and visual working memory, selective attention, inhibitory control, cognitive flexibility, and planning. RESULTS: Patients showed declines in all measures evaluated, except for a measure reaction time of inhibitory control. Auditory working memory was correlated to selective attention, inhibition, flexibility and planning while Visual working memory to planning and flexibility. CONCLUSION: The present study suggests that working memory and executive functions deficits are present in patients with schizophrenia in the Brazilian sample evaluated. Alterations in executive functions may lead to incapacity of operation of processes of working memory. These findings may contribute to delineate and develop new strategies of schizophrenia treatment in the Brazilian population.
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spelling Working memory assessment in schizophrenia and its correlation with executive functions abilityAvaliação da memória de trabalho na esquizofrenia e sua correlação com habilidades de funções executivasMemoryCognitionSchizophreniaAttentionEvaluationMemóriaCogniçãoEsquizofreniaAtençãoAvaliaçãoOBJECTIVE: Working memory impairment is common in schizophrenia and is possibly a cause of multiple features of the disorder. However few studies have replicated such findings of impairment patterns in Brazilian samples. The main target of this study was to assess auditory and visual working memory in patients with schizophrenia, to assess if they work as separate systems, and to correlate working memory deficits with executive functions. METHOD: Twenty subjects with schizophrenia and twenty healthy subjects matched by gender, age, and schooling have participated. The abilities assessed were auditory and visual working memory, selective attention, inhibitory control, cognitive flexibility, and planning. RESULTS: Patients showed declines in all measures evaluated, except for a measure reaction time of inhibitory control. Auditory working memory was correlated to selective attention, inhibition, flexibility and planning while Visual working memory to planning and flexibility. CONCLUSION: The present study suggests that working memory and executive functions deficits are present in patients with schizophrenia in the Brazilian sample evaluated. Alterations in executive functions may lead to incapacity of operation of processes of working memory. These findings may contribute to delineate and develop new strategies of schizophrenia treatment in the Brazilian population.OBJETIVO: Prejuízos em memória de trabalho são comuns na esquizofrenia e possíveis causas de múltiplas características do transtorno. Entretanto, poucos estudos reproduziram achados de padrões específicos de déficits em amostras brasileiras de pacientes com esquizofrenia. O objetivo desta pesquisa foi avaliar a memória de trabalho auditiva e visual na esquizofrenia, verificar se estas habilidades operam como dois sistemas separados, e relacionar possíveis déficits de memória de trabalho com habilidades de funções executivas. MÉTODO: Foram incluídos 20 indivíduos com esquizofrenia e 20 indivíduos saudáveis pareados quanto a sexo, idade e escolaridade. As habilidades avaliadas foram memória de trabalho auditiva e visual, atenção seletiva, controle inibitório, flexibilidade cognitiva e planejamento. RESULTADOS: Os pacientes demonstraram prejuízos em todas as medidas dos testes, exceto em tempo de reação de controle inibitório. Pacientes apresentaram significante correlação entre MT auditiva com medidas de atenção seletiva, controle inibitório, flexibilidade e planejamento. Memória de trabalho visual apresentou correlações com planejamento e flexibilidade. CONCLUSÃO: Este estudo sugere que déficits em memória de trabalho e funções executivas estão presentes em pacientes esquizofrênicos na amostra brasileira avaliada. Alterações nas funções executivas podem levar a incapacidade de adequadas operações de memória de trabalho. Esses achados podem contribuir no delineamento de novos procedimentos de intervenção na esquizofrenia em populações brasileiras.Universidade Federal de São Paulo (UNIFESP) Interdisciplinary Lab of Clinical Neurosciences Department of PsychiatryUniversidade Federal de São Paulo (UNIFESP) PROESQ Department of PsychiatryUniversidade Mackenzie Development Disturbances Post-Graduate ProgramBrain Institute Research and Teaching Institute Hospital Israelita Albert EinsteinUniversidade São Francisco Post-Graduate Program in PsychologyUniversidade São Francisco Graduate Program in PsychologyUNIFESP, Interdisciplinary Lab of Clinical Neurosciences Department of PsychiatryUNIFESP, PROESQ Department of PsychiatrySciELOFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Associação Brasileira de Psiquiatria - ABPUniversidade Federal de São Paulo (UNIFESP)Universidade Mackenzie Development Disturbances Post-Graduate ProgramBrain Institute Research and Teaching Institute Hospital Israelita Albert EinsteinUniversidade São Francisco Post-Graduate Program in PsychologyUniversidade São Francisco Graduate Program in PsychologyBerberian, Arthur de Almeida [UNIFESP]Trevisan, Bruna ToniettiMoriyama, Tais Silveira [UNIFESP]Montiel, José MariaOliveira, José Ari Carletti deSeabra, Alessandra Gotuzo2015-06-14T13:41:06Z2015-06-14T13:41:06Z2009-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion219-226application/pdfhttp://dx.doi.org/10.1590/S1516-44462009000300007BERBERIAN, Arthur de Almeida et al . Working memory assessment in schizophrenia and its correlation with executive functions ability. Rev. Bras. Psiquiatr., São Paulo , v. 31, n. 3, p. 219-226, set. 200910.1590/S1516-44462009000300007S1516-44462009000300007.pdf1516-4446S1516-44462009000300007http://repositorio.unifesp.br/handle/11600/5198WOS:000270229900006engRevista Brasileira de Psiquiatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T07:15:10Zoai:repositorio.unifesp.br/:11600/5198Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T07:15:10Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Working memory assessment in schizophrenia and its correlation with executive functions ability
Avaliação da memória de trabalho na esquizofrenia e sua correlação com habilidades de funções executivas
title Working memory assessment in schizophrenia and its correlation with executive functions ability
spellingShingle Working memory assessment in schizophrenia and its correlation with executive functions ability
Berberian, Arthur de Almeida [UNIFESP]
Memory
Cognition
Schizophrenia
Attention
Evaluation
Memória
Cognição
Esquizofrenia
Atenção
Avaliação
title_short Working memory assessment in schizophrenia and its correlation with executive functions ability
title_full Working memory assessment in schizophrenia and its correlation with executive functions ability
title_fullStr Working memory assessment in schizophrenia and its correlation with executive functions ability
title_full_unstemmed Working memory assessment in schizophrenia and its correlation with executive functions ability
title_sort Working memory assessment in schizophrenia and its correlation with executive functions ability
author Berberian, Arthur de Almeida [UNIFESP]
author_facet Berberian, Arthur de Almeida [UNIFESP]
Trevisan, Bruna Tonietti
Moriyama, Tais Silveira [UNIFESP]
Montiel, José Maria
Oliveira, José Ari Carletti de
Seabra, Alessandra Gotuzo
author_role author
author2 Trevisan, Bruna Tonietti
Moriyama, Tais Silveira [UNIFESP]
Montiel, José Maria
Oliveira, José Ari Carletti de
Seabra, Alessandra Gotuzo
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Universidade Mackenzie Development Disturbances Post-Graduate Program
Brain Institute Research and Teaching Institute Hospital Israelita Albert Einstein
Universidade São Francisco Post-Graduate Program in Psychology
Universidade São Francisco Graduate Program in Psychology
dc.contributor.author.fl_str_mv Berberian, Arthur de Almeida [UNIFESP]
Trevisan, Bruna Tonietti
Moriyama, Tais Silveira [UNIFESP]
Montiel, José Maria
Oliveira, José Ari Carletti de
Seabra, Alessandra Gotuzo
dc.subject.por.fl_str_mv Memory
Cognition
Schizophrenia
Attention
Evaluation
Memória
Cognição
Esquizofrenia
Atenção
Avaliação
topic Memory
Cognition
Schizophrenia
Attention
Evaluation
Memória
Cognição
Esquizofrenia
Atenção
Avaliação
description OBJECTIVE: Working memory impairment is common in schizophrenia and is possibly a cause of multiple features of the disorder. However few studies have replicated such findings of impairment patterns in Brazilian samples. The main target of this study was to assess auditory and visual working memory in patients with schizophrenia, to assess if they work as separate systems, and to correlate working memory deficits with executive functions. METHOD: Twenty subjects with schizophrenia and twenty healthy subjects matched by gender, age, and schooling have participated. The abilities assessed were auditory and visual working memory, selective attention, inhibitory control, cognitive flexibility, and planning. RESULTS: Patients showed declines in all measures evaluated, except for a measure reaction time of inhibitory control. Auditory working memory was correlated to selective attention, inhibition, flexibility and planning while Visual working memory to planning and flexibility. CONCLUSION: The present study suggests that working memory and executive functions deficits are present in patients with schizophrenia in the Brazilian sample evaluated. Alterations in executive functions may lead to incapacity of operation of processes of working memory. These findings may contribute to delineate and develop new strategies of schizophrenia treatment in the Brazilian population.
publishDate 2009
dc.date.none.fl_str_mv 2009-09-01
2015-06-14T13:41:06Z
2015-06-14T13:41:06Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1516-44462009000300007
BERBERIAN, Arthur de Almeida et al . Working memory assessment in schizophrenia and its correlation with executive functions ability. Rev. Bras. Psiquiatr., São Paulo , v. 31, n. 3, p. 219-226, set. 2009
10.1590/S1516-44462009000300007
S1516-44462009000300007.pdf
1516-4446
S1516-44462009000300007
http://repositorio.unifesp.br/handle/11600/5198
WOS:000270229900006
url http://dx.doi.org/10.1590/S1516-44462009000300007
http://repositorio.unifesp.br/handle/11600/5198
identifier_str_mv BERBERIAN, Arthur de Almeida et al . Working memory assessment in schizophrenia and its correlation with executive functions ability. Rev. Bras. Psiquiatr., São Paulo , v. 31, n. 3, p. 219-226, set. 2009
10.1590/S1516-44462009000300007
S1516-44462009000300007.pdf
1516-4446
S1516-44462009000300007
WOS:000270229900006
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista Brasileira de Psiquiatria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 219-226
application/pdf
dc.publisher.none.fl_str_mv Associação Brasileira de Psiquiatria - ABP
publisher.none.fl_str_mv Associação Brasileira de Psiquiatria - ABP
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268313866338304

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