Alterações oculares na doença de Chagas crônica: comprovação na região endêmica de Água Comprida (MG)

• Autor(a) principal: Prata, João Antonio
• Data de Publicação: 2000
• Outros Autores: Prata Junior, João Antonio [UNIFESP], Correia, Dalmo, Prata, Aluizio R.
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0004-27492000000600003; http://repositorio.unifesp.br/handle/11600/1072
• topic: Anisocoria; Intraocular pressure alterations; Chagas' disease; Anisocoria; Pressão intra-ocular, alterações; Doença de Chagas

Purpose: To prove, also at Água Comprida (MG), the higher incidence of anisocoria and lower IOP levels in chagasic patients formerly detected at Mambai (GO), both endemic Chagas' areas. Material and methods: In a prospective, masked and paired study, 190 patients were evaluated. Pairing was according to age, sex and race. Pupil diameter was determined in 84 pairs using photography. Anisocoria was considered when a difference > 0.3 mm was observed. IOP was analyzed in 95 pairs. Results: 25 chagasic patients (29.8%) and 10 controls (11.9%) had anisocoria. This difference was statistically significant (p = 0.007). There were no differences in pupil diameter between chagasic patients and controls for OD or OS. Chagasic patients had a mean IOP of 11.3±2.5 mmHg (OD) and 11.3±2.4 mmHg (OS) and controls showed mean IOPs of 13.1±2.6 and 13.1±2.5 mmHg respectively. The differences between chagasic patients and controls were statistically significant for OD and OS (pOD=pOE <0.0001). The comparison of IOP levels according to sex was also statistically significant (females p =0.002, males p= 0.003). Conclusion: The results demonstrate a higher frequency of anisocoria and lower IOP levels in chronic chagasic patients.