del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts

Detalhes bibliográficos
Autor(a) principal: Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]
Data de Publicação: 1997
Outros Autores: Stéfano, José Tadeu [UNIFESP], Valério, Rosana Maria [UNIFESP], Romeo, Maura [UNIFESP], Rodrigues, Maria Madalena [UNIFESP], Kerbauy, José [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S1516-31801997000400010
http://repositorio.unifesp.br/handle/11600/507
Resumo: We present the case of a patient with MDS RARS subtype with loss of part of the long arm of chromosome 11 del 11(q23). This a cytogenetic abnormality that occurs in 7% to 20% of RARS cases not related to poor prognosis. It seems that this deletion is a marker of iron overload in MDS.
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repository_id_str 3465
spelling del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblastsMyelodysplasiaIron overloadRefractory anemia with ringed sideroblastsKaryotypeWe present the case of a patient with MDS RARS subtype with loss of part of the long arm of chromosome 11 del 11(q23). This a cytogenetic abnormality that occurs in 7% to 20% of RARS cases not related to poor prognosis. It seems that this deletion is a marker of iron overload in MDS.Apresentamos o caso de paciente com Síndrome Mielodisplásia (SMD) sublito Anemia Refratária com Sideroblastos em Anel (ARSA) com perda do braço longo do cromossomo 11 [del (q23)]. Trata-se de alteração citogenética que ocorre entre 7 e 20% dos casos de ARSA não se correlacionando a mau prognóstico, ou seja, evolução para leucemia aguda. Aparentemente, esta deleção é um marcador de sobrecarga de ferro na SMD.Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM)UNIFESP, EPMSciELOAssociação Paulista de Medicina - APMUniversidade Federal de São Paulo (UNIFESP)Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]Stéfano, José Tadeu [UNIFESP]Valério, Rosana Maria [UNIFESP]Romeo, Maura [UNIFESP]Rodrigues, Maria Madalena [UNIFESP]Kerbauy, José [UNIFESP]2015-06-14T13:24:37Z2015-06-14T13:24:37Z1997-08-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1513-1515application/pdfhttp://dx.doi.org/10.1590/S1516-31801997000400010São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 4, p. 1513-1515, 1997.10.1590/S1516-31801997000400010S1516-31801997000400010.pdf1516-3180S1516-31801997000400010http://repositorio.unifesp.br/handle/11600/507engSão Paulo Medical Journalinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T06:18:18Zoai:repositorio.unifesp.br/:11600/507Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T06:18:18Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts
title del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts
spellingShingle del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts
Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]
Myelodysplasia
Iron overload
Refractory anemia with ringed sideroblasts
Karyotype
title_short del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts
title_full del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts
title_fullStr del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts
title_full_unstemmed del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts
title_sort del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts
author Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]
author_facet Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]
Stéfano, José Tadeu [UNIFESP]
Valério, Rosana Maria [UNIFESP]
Romeo, Maura [UNIFESP]
Rodrigues, Maria Madalena [UNIFESP]
Kerbauy, José [UNIFESP]
author_role author
author2 Stéfano, José Tadeu [UNIFESP]
Valério, Rosana Maria [UNIFESP]
Romeo, Maura [UNIFESP]
Rodrigues, Maria Madalena [UNIFESP]
Kerbauy, José [UNIFESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Chauffaille, Maria de Lourdes Lopes Ferrari [UNIFESP]
Stéfano, José Tadeu [UNIFESP]
Valério, Rosana Maria [UNIFESP]
Romeo, Maura [UNIFESP]
Rodrigues, Maria Madalena [UNIFESP]
Kerbauy, José [UNIFESP]
dc.subject.por.fl_str_mv Myelodysplasia
Iron overload
Refractory anemia with ringed sideroblasts
Karyotype
topic Myelodysplasia
Iron overload
Refractory anemia with ringed sideroblasts
Karyotype
description We present the case of a patient with MDS RARS subtype with loss of part of the long arm of chromosome 11 del 11(q23). This a cytogenetic abnormality that occurs in 7% to 20% of RARS cases not related to poor prognosis. It seems that this deletion is a marker of iron overload in MDS.
publishDate 1997
dc.date.none.fl_str_mv 1997-08-01
2015-06-14T13:24:37Z
2015-06-14T13:24:37Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1516-31801997000400010
São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 4, p. 1513-1515, 1997.
10.1590/S1516-31801997000400010
S1516-31801997000400010.pdf
1516-3180
S1516-31801997000400010
http://repositorio.unifesp.br/handle/11600/507
url http://dx.doi.org/10.1590/S1516-31801997000400010
http://repositorio.unifesp.br/handle/11600/507
identifier_str_mv São Paulo Medical Journal. Associação Paulista de Medicina - APM, v. 115, n. 4, p. 1513-1515, 1997.
10.1590/S1516-31801997000400010
S1516-31801997000400010.pdf
1516-3180
S1516-31801997000400010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv São Paulo Medical Journal
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1513-1515
application/pdf
dc.publisher.none.fl_str_mv Associação Paulista de Medicina - APM
publisher.none.fl_str_mv Associação Paulista de Medicina - APM
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
_version_ 1814268394644439040

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