Epidemiology of Behcet Disease
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.3109/09273948.2012.723112 http://repositorio.unifesp.br/handle/11600/35333 |
Resumo: | Behcet disease (BD) is a multisystem inflammatory disorder that is an important cause of morbidity worldwide. BD is most common along the ancient Silk Road route in the Far East and Mediterranean basin. the eye is the most commonly involved organ in BD patients. the prototypical form of involvement is a relapsing remitting panuveitis and retinal vasculitis. Less commonly, BD may present in the form of conjunctivitis, conjunctival ulcers, keratitis, episcleritis, scleritis, and extraocular muscle paralysis. Uveitis in BD carries significant implications for the patient, because it is a chronic recurrent disease characterized by explosive attacks of severe inflammation that may cause significant, cumulative damage to the intraocular structures. This review summarizes the epidemiology of systemic and ocular clinical features of BD with particular focus on risk factors, clinical characteristics, complications, and prognosis of BD-associated uveitis. |
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Epidemiology of Behcet DiseaseBehcet diseaseComplicationsEpidemiologyUveitisVisual lossHistoryBehcet disease (BD) is a multisystem inflammatory disorder that is an important cause of morbidity worldwide. BD is most common along the ancient Silk Road route in the Far East and Mediterranean basin. the eye is the most commonly involved organ in BD patients. the prototypical form of involvement is a relapsing remitting panuveitis and retinal vasculitis. Less commonly, BD may present in the form of conjunctivitis, conjunctival ulcers, keratitis, episcleritis, scleritis, and extraocular muscle paralysis. Uveitis in BD carries significant implications for the patient, because it is a chronic recurrent disease characterized by explosive attacks of severe inflammation that may cause significant, cumulative damage to the intraocular structures. This review summarizes the epidemiology of systemic and ocular clinical features of BD with particular focus on risk factors, clinical characteristics, complications, and prognosis of BD-associated uveitis.Fattouma Bourguiba Univ Hosp, Fac Med, Dept Ophthalmol, Monastir, TunisiaUniv Monastir, Monastir, TunisiaUniv Roma La Sapienza, Dipartimento Organi Senso, Rome, ItalyUniversidade Federal de São Paulo, Dept Ophthalmol, São Paulo, BrazilUniv Penn, Scheie Eye Inst, Dept Ophthalmol, Ctr Prevent Ophthalmol & Biostat, Philadelphia, PA 19104 USAUniv Penn, Dept Biostat & Epidemiol, Ctr Clin Epidemiol & Biostat, Philadelphia, PA 19104 USAUniversidade Federal de São Paulo, Dept Ophthalmol, São Paulo, BrazilWeb of ScienceInforma HealthcareFattouma Bourguiba Univ HospUniv MonastirUniv Roma La SapienzaUniversidade Federal de São Paulo (UNIFESP)Univ PennKhairallah, MoncefAccorinti, MassimoMuccioli, Cristina [UNIFESP]Kahloun, RimKempen, John H.2016-01-24T14:27:46Z2016-01-24T14:27:46Z2012-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion324-335http://dx.doi.org/10.3109/09273948.2012.723112Ocular Immunology and Inflammation. London: Informa Healthcare, v. 20, n. 5, p. 324-335, 2012.10.3109/09273948.2012.7231120927-3948http://repositorio.unifesp.br/handle/11600/35333WOS:000309471900002engOcular Immunology and Inflammationinfo:eu-repo/semantics/openAccesshttp://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdfreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2016-01-24T12:27:46Zoai:repositorio.unifesp.br/:11600/35333Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652016-01-24T12:27:46Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Epidemiology of Behcet Disease |
title |
Epidemiology of Behcet Disease |
spellingShingle |
Epidemiology of Behcet Disease Khairallah, Moncef Behcet disease Complications Epidemiology Uveitis Visual loss History |
title_short |
Epidemiology of Behcet Disease |
title_full |
Epidemiology of Behcet Disease |
title_fullStr |
Epidemiology of Behcet Disease |
title_full_unstemmed |
Epidemiology of Behcet Disease |
title_sort |
Epidemiology of Behcet Disease |
author |
Khairallah, Moncef |
author_facet |
Khairallah, Moncef Accorinti, Massimo Muccioli, Cristina [UNIFESP] Kahloun, Rim Kempen, John H. |
author_role |
author |
author2 |
Accorinti, Massimo Muccioli, Cristina [UNIFESP] Kahloun, Rim Kempen, John H. |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Fattouma Bourguiba Univ Hosp Univ Monastir Univ Roma La Sapienza Universidade Federal de São Paulo (UNIFESP) Univ Penn |
dc.contributor.author.fl_str_mv |
Khairallah, Moncef Accorinti, Massimo Muccioli, Cristina [UNIFESP] Kahloun, Rim Kempen, John H. |
dc.subject.por.fl_str_mv |
Behcet disease Complications Epidemiology Uveitis Visual loss History |
topic |
Behcet disease Complications Epidemiology Uveitis Visual loss History |
description |
Behcet disease (BD) is a multisystem inflammatory disorder that is an important cause of morbidity worldwide. BD is most common along the ancient Silk Road route in the Far East and Mediterranean basin. the eye is the most commonly involved organ in BD patients. the prototypical form of involvement is a relapsing remitting panuveitis and retinal vasculitis. Less commonly, BD may present in the form of conjunctivitis, conjunctival ulcers, keratitis, episcleritis, scleritis, and extraocular muscle paralysis. Uveitis in BD carries significant implications for the patient, because it is a chronic recurrent disease characterized by explosive attacks of severe inflammation that may cause significant, cumulative damage to the intraocular structures. This review summarizes the epidemiology of systemic and ocular clinical features of BD with particular focus on risk factors, clinical characteristics, complications, and prognosis of BD-associated uveitis. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-10-01 2016-01-24T14:27:46Z 2016-01-24T14:27:46Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3109/09273948.2012.723112 Ocular Immunology and Inflammation. London: Informa Healthcare, v. 20, n. 5, p. 324-335, 2012. 10.3109/09273948.2012.723112 0927-3948 http://repositorio.unifesp.br/handle/11600/35333 WOS:000309471900002 |
url |
http://dx.doi.org/10.3109/09273948.2012.723112 http://repositorio.unifesp.br/handle/11600/35333 |
identifier_str_mv |
Ocular Immunology and Inflammation. London: Informa Healthcare, v. 20, n. 5, p. 324-335, 2012. 10.3109/09273948.2012.723112 0927-3948 WOS:000309471900002 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ocular Immunology and Inflammation |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess http://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf |
eu_rights_str_mv |
openAccess |
rights_invalid_str_mv |
http://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf |
dc.format.none.fl_str_mv |
324-335 |
dc.publisher.none.fl_str_mv |
Informa Healthcare |
publisher.none.fl_str_mv |
Informa Healthcare |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268436581187584 |