Aborto espontâneo de repetição e atopia
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNIFESP |
dARK ID: | ark:/48912/0013000019v0k |
Texto Completo: | http://dx.doi.org/10.1590/S0100-72032003000500005 http://repositorio.unifesp.br/handle/11600/1747 |
Resumo: | PURPOSE: to evaluate whether there is an association between recurrent spontaneous abortion and atopy. METHODS: this was a case-control study with 230 women: 71 with a history of recurrent spontaneous abortion (group A) and 159 with a history of successful pregnancy (group B). The evaluation included a questionnaire in order to investigate the personal history of atopy, considering symptoms of atopic dermatitis, urticaria, rhinitis, asthma, conjunctivitis and gastric or intestinal symptoms. The presence of specific IgE in response to a pool of inhalants, Phadiatop, detected by an enzymatic fluorescence reaction in blood was also investigated. The data were analyzed by Fisher's exact test and a p value < 0.05 was set as level of significance. RESULTS: a positive history of atopy was observed in 57.7% of group A patients and in 55.3% of group B patients. The incidence of positive IgE against Phadiatop was 38% and 33.9% in groups A and B, respectively. Association of allergy disease with positive Phadiatop (presence of specific IgE) was detected in 28.2% of group A and in 22% of group B patients. There was no significant difference between the groups. CONCLUSIONS: we did not observe any association between recurrent spontaneous abortion and atopy. |
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Aborto espontâneo de repetição e atopiaRecurrent spontaneous abortion and atopyAbortionAtopyPregnancyCytokinesImmunoglobulinsAbortoAtopiaGravidezCitocinasImunoglobulinaPURPOSE: to evaluate whether there is an association between recurrent spontaneous abortion and atopy. METHODS: this was a case-control study with 230 women: 71 with a history of recurrent spontaneous abortion (group A) and 159 with a history of successful pregnancy (group B). The evaluation included a questionnaire in order to investigate the personal history of atopy, considering symptoms of atopic dermatitis, urticaria, rhinitis, asthma, conjunctivitis and gastric or intestinal symptoms. The presence of specific IgE in response to a pool of inhalants, Phadiatop, detected by an enzymatic fluorescence reaction in blood was also investigated. The data were analyzed by Fisher's exact test and a p value < 0.05 was set as level of significance. RESULTS: a positive history of atopy was observed in 57.7% of group A patients and in 55.3% of group B patients. The incidence of positive IgE against Phadiatop was 38% and 33.9% in groups A and B, respectively. Association of allergy disease with positive Phadiatop (presence of specific IgE) was detected in 28.2% of group A and in 22% of group B patients. There was no significant difference between the groups. CONCLUSIONS: we did not observe any association between recurrent spontaneous abortion and atopy.OBJETIVO: nosso objetivo foi avaliar se existe associação entre aborto espontâneo recorrente e atopia. MÉTODO: foi realizado estudo caso-controle prospectivo, envolvendo 230 mulheres: 71 com história de aborto espontâneo recorrente (grupo A) e 159 com história de sucesso gestacional (grupo B). A avaliação incluiu questionário realizado com o objetivo de investigar a história pessoal de atopia pelo relato de dermatite atópica, urticária, rinite, asma, conjuntivite e manifestações gastrointestinais. Foi também determinada a presença de IgE específica a pool de inalantes (Phadiatop), pela realização no sangue de reação de fluorescência enzimática. Os resultados foram analisados pelo teste exato de Fisher, tendo sido considerado significante p<0,05. RESULTADOS: história positiva de atopia foi identificada em 57,7% das pacientes do grupo A e em 53,3% do grupo B. Resultados positivos da presença de IgE específica pelo Phadiatop foram detectados em 38% e 33,9% das pacientes do grupo A e B, respectivamente. Encontro de associação de doenças alérgicas e a presença de IgE específica foi observado em 28,2% das mulheres do grupo A e em 22% do grupo B. Não foi detectada diferença significante entre os grupos. CONCLUSÕES: este trabalho não observou associação entre a ocorrência de aborto espontâneo de repetição e atopia.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de ObstetríciaUNIFESP, EPM, Depto. de ObstetríciaSciELOFederação Brasileira das Sociedades de Ginecologia e ObstetríciaUniversidade Federal de São Paulo (UNIFESP)Mattar, Rosiane [UNIFESP]Camano, LuizDaher, Silvia [UNIFESP]2015-06-14T13:30:02Z2015-06-14T13:30:02Z2003-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion331-335application/pdfhttp://dx.doi.org/10.1590/S0100-72032003000500005Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 25, n. 5, p. 331-335, 2003.10.1590/S0100-72032003000500005S0100-72032003000500005.pdf0100-7203S0100-72032003000500005http://repositorio.unifesp.br/handle/11600/1747ark:/48912/0013000019v0kporRevista Brasileira de Ginecologia e Obstetríciainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T16:38:46Zoai:repositorio.unifesp.br/:11600/1747Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T21:06:16.440115Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Aborto espontâneo de repetição e atopia Recurrent spontaneous abortion and atopy |
title |
Aborto espontâneo de repetição e atopia |
spellingShingle |
Aborto espontâneo de repetição e atopia Mattar, Rosiane [UNIFESP] Abortion Atopy Pregnancy Cytokines Immunoglobulins Aborto Atopia Gravidez Citocinas Imunoglobulina |
title_short |
Aborto espontâneo de repetição e atopia |
title_full |
Aborto espontâneo de repetição e atopia |
title_fullStr |
Aborto espontâneo de repetição e atopia |
title_full_unstemmed |
Aborto espontâneo de repetição e atopia |
title_sort |
Aborto espontâneo de repetição e atopia |
author |
Mattar, Rosiane [UNIFESP] |
author_facet |
Mattar, Rosiane [UNIFESP] Camano, Luiz Daher, Silvia [UNIFESP] |
author_role |
author |
author2 |
Camano, Luiz Daher, Silvia [UNIFESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Mattar, Rosiane [UNIFESP] Camano, Luiz Daher, Silvia [UNIFESP] |
dc.subject.por.fl_str_mv |
Abortion Atopy Pregnancy Cytokines Immunoglobulins Aborto Atopia Gravidez Citocinas Imunoglobulina |
topic |
Abortion Atopy Pregnancy Cytokines Immunoglobulins Aborto Atopia Gravidez Citocinas Imunoglobulina |
description |
PURPOSE: to evaluate whether there is an association between recurrent spontaneous abortion and atopy. METHODS: this was a case-control study with 230 women: 71 with a history of recurrent spontaneous abortion (group A) and 159 with a history of successful pregnancy (group B). The evaluation included a questionnaire in order to investigate the personal history of atopy, considering symptoms of atopic dermatitis, urticaria, rhinitis, asthma, conjunctivitis and gastric or intestinal symptoms. The presence of specific IgE in response to a pool of inhalants, Phadiatop, detected by an enzymatic fluorescence reaction in blood was also investigated. The data were analyzed by Fisher's exact test and a p value < 0.05 was set as level of significance. RESULTS: a positive history of atopy was observed in 57.7% of group A patients and in 55.3% of group B patients. The incidence of positive IgE against Phadiatop was 38% and 33.9% in groups A and B, respectively. Association of allergy disease with positive Phadiatop (presence of specific IgE) was detected in 28.2% of group A and in 22% of group B patients. There was no significant difference between the groups. CONCLUSIONS: we did not observe any association between recurrent spontaneous abortion and atopy. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-06-01 2015-06-14T13:30:02Z 2015-06-14T13:30:02Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0100-72032003000500005 Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 25, n. 5, p. 331-335, 2003. 10.1590/S0100-72032003000500005 S0100-72032003000500005.pdf 0100-7203 S0100-72032003000500005 http://repositorio.unifesp.br/handle/11600/1747 |
dc.identifier.dark.fl_str_mv |
ark:/48912/0013000019v0k |
url |
http://dx.doi.org/10.1590/S0100-72032003000500005 http://repositorio.unifesp.br/handle/11600/1747 |
identifier_str_mv |
Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 25, n. 5, p. 331-335, 2003. 10.1590/S0100-72032003000500005 S0100-72032003000500005.pdf 0100-7203 S0100-72032003000500005 ark:/48912/0013000019v0k |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista Brasileira de Ginecologia e Obstetrícia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
331-335 application/pdf |
dc.publisher.none.fl_str_mv |
Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
publisher.none.fl_str_mv |
Federação Brasileira das Sociedades de Ginecologia e Obstetrícia |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
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1818602603267751936 |