Aborto espontâneo de repetição e atopia

Detalhes bibliográficos
Autor(a) principal: Mattar, Rosiane [UNIFESP]
Data de Publicação: 2003
Outros Autores: Camano, Luiz, Daher, Silvia [UNIFESP]
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNIFESP
dARK ID: ark:/48912/0013000019v0k
Texto Completo: http://dx.doi.org/10.1590/S0100-72032003000500005
http://repositorio.unifesp.br/handle/11600/1747
Resumo: PURPOSE: to evaluate whether there is an association between recurrent spontaneous abortion and atopy. METHODS: this was a case-control study with 230 women: 71 with a history of recurrent spontaneous abortion (group A) and 159 with a history of successful pregnancy (group B). The evaluation included a questionnaire in order to investigate the personal history of atopy, considering symptoms of atopic dermatitis, urticaria, rhinitis, asthma, conjunctivitis and gastric or intestinal symptoms. The presence of specific IgE in response to a pool of inhalants, Phadiatop, detected by an enzymatic fluorescence reaction in blood was also investigated. The data were analyzed by Fisher's exact test and a p value < 0.05 was set as level of significance. RESULTS: a positive history of atopy was observed in 57.7% of group A patients and in 55.3% of group B patients. The incidence of positive IgE against Phadiatop was 38% and 33.9% in groups A and B, respectively. Association of allergy disease with positive Phadiatop (presence of specific IgE) was detected in 28.2% of group A and in 22% of group B patients. There was no significant difference between the groups. CONCLUSIONS: we did not observe any association between recurrent spontaneous abortion and atopy.
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spelling Aborto espontâneo de repetição e atopiaRecurrent spontaneous abortion and atopyAbortionAtopyPregnancyCytokinesImmunoglobulinsAbortoAtopiaGravidezCitocinasImunoglobulinaPURPOSE: to evaluate whether there is an association between recurrent spontaneous abortion and atopy. METHODS: this was a case-control study with 230 women: 71 with a history of recurrent spontaneous abortion (group A) and 159 with a history of successful pregnancy (group B). The evaluation included a questionnaire in order to investigate the personal history of atopy, considering symptoms of atopic dermatitis, urticaria, rhinitis, asthma, conjunctivitis and gastric or intestinal symptoms. The presence of specific IgE in response to a pool of inhalants, Phadiatop, detected by an enzymatic fluorescence reaction in blood was also investigated. The data were analyzed by Fisher's exact test and a p value < 0.05 was set as level of significance. RESULTS: a positive history of atopy was observed in 57.7% of group A patients and in 55.3% of group B patients. The incidence of positive IgE against Phadiatop was 38% and 33.9% in groups A and B, respectively. Association of allergy disease with positive Phadiatop (presence of specific IgE) was detected in 28.2% of group A and in 22% of group B patients. There was no significant difference between the groups. CONCLUSIONS: we did not observe any association between recurrent spontaneous abortion and atopy.OBJETIVO: nosso objetivo foi avaliar se existe associação entre aborto espontâneo recorrente e atopia. MÉTODO: foi realizado estudo caso-controle prospectivo, envolvendo 230 mulheres: 71 com história de aborto espontâneo recorrente (grupo A) e 159 com história de sucesso gestacional (grupo B). A avaliação incluiu questionário realizado com o objetivo de investigar a história pessoal de atopia pelo relato de dermatite atópica, urticária, rinite, asma, conjuntivite e manifestações gastrointestinais. Foi também determinada a presença de IgE específica a pool de inalantes (Phadiatop), pela realização no sangue de reação de fluorescência enzimática. Os resultados foram analisados pelo teste exato de Fisher, tendo sido considerado significante p<0,05. RESULTADOS: história positiva de atopia foi identificada em 57,7% das pacientes do grupo A e em 53,3% do grupo B. Resultados positivos da presença de IgE específica pelo Phadiatop foram detectados em 38% e 33,9% das pacientes do grupo A e B, respectivamente. Encontro de associação de doenças alérgicas e a presença de IgE específica foi observado em 28,2% das mulheres do grupo A e em 22% do grupo B. Não foi detectada diferença significante entre os grupos. CONCLUSÕES: este trabalho não observou associação entre a ocorrência de aborto espontâneo de repetição e atopia.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Departamento de ObstetríciaUNIFESP, EPM, Depto. de ObstetríciaSciELOFederação Brasileira das Sociedades de Ginecologia e ObstetríciaUniversidade Federal de São Paulo (UNIFESP)Mattar, Rosiane [UNIFESP]Camano, LuizDaher, Silvia [UNIFESP]2015-06-14T13:30:02Z2015-06-14T13:30:02Z2003-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion331-335application/pdfhttp://dx.doi.org/10.1590/S0100-72032003000500005Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 25, n. 5, p. 331-335, 2003.10.1590/S0100-72032003000500005S0100-72032003000500005.pdf0100-7203S0100-72032003000500005http://repositorio.unifesp.br/handle/11600/1747ark:/48912/0013000019v0kporRevista Brasileira de Ginecologia e Obstetríciainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-29T16:38:46Zoai:repositorio.unifesp.br/:11600/1747Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-12-11T21:06:16.440115Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Aborto espontâneo de repetição e atopia
Recurrent spontaneous abortion and atopy
title Aborto espontâneo de repetição e atopia
spellingShingle Aborto espontâneo de repetição e atopia
Mattar, Rosiane [UNIFESP]
Abortion
Atopy
Pregnancy
Cytokines
Immunoglobulins
Aborto
Atopia
Gravidez
Citocinas
Imunoglobulina
title_short Aborto espontâneo de repetição e atopia
title_full Aborto espontâneo de repetição e atopia
title_fullStr Aborto espontâneo de repetição e atopia
title_full_unstemmed Aborto espontâneo de repetição e atopia
title_sort Aborto espontâneo de repetição e atopia
author Mattar, Rosiane [UNIFESP]
author_facet Mattar, Rosiane [UNIFESP]
Camano, Luiz
Daher, Silvia [UNIFESP]
author_role author
author2 Camano, Luiz
Daher, Silvia [UNIFESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Mattar, Rosiane [UNIFESP]
Camano, Luiz
Daher, Silvia [UNIFESP]
dc.subject.por.fl_str_mv Abortion
Atopy
Pregnancy
Cytokines
Immunoglobulins
Aborto
Atopia
Gravidez
Citocinas
Imunoglobulina
topic Abortion
Atopy
Pregnancy
Cytokines
Immunoglobulins
Aborto
Atopia
Gravidez
Citocinas
Imunoglobulina
description PURPOSE: to evaluate whether there is an association between recurrent spontaneous abortion and atopy. METHODS: this was a case-control study with 230 women: 71 with a history of recurrent spontaneous abortion (group A) and 159 with a history of successful pregnancy (group B). The evaluation included a questionnaire in order to investigate the personal history of atopy, considering symptoms of atopic dermatitis, urticaria, rhinitis, asthma, conjunctivitis and gastric or intestinal symptoms. The presence of specific IgE in response to a pool of inhalants, Phadiatop, detected by an enzymatic fluorescence reaction in blood was also investigated. The data were analyzed by Fisher's exact test and a p value < 0.05 was set as level of significance. RESULTS: a positive history of atopy was observed in 57.7% of group A patients and in 55.3% of group B patients. The incidence of positive IgE against Phadiatop was 38% and 33.9% in groups A and B, respectively. Association of allergy disease with positive Phadiatop (presence of specific IgE) was detected in 28.2% of group A and in 22% of group B patients. There was no significant difference between the groups. CONCLUSIONS: we did not observe any association between recurrent spontaneous abortion and atopy.
publishDate 2003
dc.date.none.fl_str_mv 2003-06-01
2015-06-14T13:30:02Z
2015-06-14T13:30:02Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0100-72032003000500005
Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 25, n. 5, p. 331-335, 2003.
10.1590/S0100-72032003000500005
S0100-72032003000500005.pdf
0100-7203
S0100-72032003000500005
http://repositorio.unifesp.br/handle/11600/1747
dc.identifier.dark.fl_str_mv ark:/48912/0013000019v0k
url http://dx.doi.org/10.1590/S0100-72032003000500005
http://repositorio.unifesp.br/handle/11600/1747
identifier_str_mv Revista Brasileira de Ginecologia e Obstetrícia. Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, v. 25, n. 5, p. 331-335, 2003.
10.1590/S0100-72032003000500005
S0100-72032003000500005.pdf
0100-7203
S0100-72032003000500005
ark:/48912/0013000019v0k
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Revista Brasileira de Ginecologia e Obstetrícia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 331-335
application/pdf
dc.publisher.none.fl_str_mv Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
publisher.none.fl_str_mv Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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