Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | https://repositorio.unifesp.br/handle/11600/58123 http://dx.doi.org/10.1007/s00737-017-0791-0 |
Resumo: | The objective of this study was to evaluate whether Vitex agnus castus is a safe and effective treatment for PMS and premenstrual dysphoric disorder (PMDD) and to discuss the implications of these findings for clinical practice. A systematic review of literature was conducted using PubMed and Scielo databases. The inclusion criteria were randomized controlled trials (RCT) using V. agnus castus in individuals with PMS or PMDD that compared this intervention with placebo or an active comparator and included a description of blinding and dropouts/withdrawals. The search was conducted by two independent investigators who reached consensus on the included trials. A total of eight RCTs were included in this study. Most studies focused on PMS, and the diagnostic criteria of PMS and PMDD changed over the years. Three different preparations of V. agnus castus (VAC) were tested, and there was significant variability in the measurement of treatment outcomes between the studies. Nevertheless, all eight studies were positive for VAC in the treatment of PMS or PMDD and VAC was overall well tolerated. Main limitations were differences in definition of diagnostic criteria, the instruments used as main outcome measures, and different preparations of VAC extracts limit the comparison of results between studies. In conclusion, the RCTs using VAC for treatment of PMS/PMDD suggested that the VAC extract is a safe and efficacious alternative to be considered for the treatment of PMS/PMDD symptoms. |
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Cerqueira, Raphael O. [UNIFESP]Frey, Benicio N.Leclerc, Emilie [UNIFESP]Brietzke, Elisa [UNIFESP]2020-09-01T13:21:12Z2020-09-01T13:21:12Z2017Archives Of Womens Mental Health. Wien, v. 20, n. 6, p. 713-719, 2017.1434-1816https://repositorio.unifesp.br/handle/11600/58123http://dx.doi.org/10.1007/s00737-017-0791-010.1007/s00737-017-0791-0WOS:000415731700001The objective of this study was to evaluate whether Vitex agnus castus is a safe and effective treatment for PMS and premenstrual dysphoric disorder (PMDD) and to discuss the implications of these findings for clinical practice. A systematic review of literature was conducted using PubMed and Scielo databases. The inclusion criteria were randomized controlled trials (RCT) using V. agnus castus in individuals with PMS or PMDD that compared this intervention with placebo or an active comparator and included a description of blinding and dropouts/withdrawals. The search was conducted by two independent investigators who reached consensus on the included trials. A total of eight RCTs were included in this study. Most studies focused on PMS, and the diagnostic criteria of PMS and PMDD changed over the years. Three different preparations of V. agnus castus (VAC) were tested, and there was significant variability in the measurement of treatment outcomes between the studies. Nevertheless, all eight studies were positive for VAC in the treatment of PMS or PMDD and VAC was overall well tolerated. Main limitations were differences in definition of diagnostic criteria, the instruments used as main outcome measures, and different preparations of VAC extracts limit the comparison of results between studies. In conclusion, the RCTs using VAC for treatment of PMS/PMDD suggested that the VAC extract is a safe and efficacious alternative to be considered for the treatment of PMS/PMDD symptoms.Univ Fed Sao Paulo, Dept Psychiat, Res Grp Behav & Mol Neurosci Bipolar Disorder, Rua Borges Lagoa,570-10th Floor,Vila Clementino, BR-04038000 Sao Paulo, BrazilMcMaster Univ, Dept Psychiat & Behav Neurosci, Hamilton, ON, CanadaSt Josephs Healthcare, Womens Hlth Concerns Clin, Hamilton, ON, CanadaSt Josephs Healthcare, Mood Disorders Program, Hamilton, ON, CanadaUniv Fed Sao Paulo, Dept Psychiat, Res Grp Behav & Mol Neurosci Bipolar Disorder, Rua Borges Lagoa,570-10th Floor,Vila Clementino, BR-04038000 Sao Paulo, BrazilWeb of Science713-719engSpringer WienArchives Of Womens Mental HealthVitex agnus castusChasteberryPremenstrual syndromePremenstrual dysphoric disorderTreatmentVitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic reviewinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleWien206info:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP11600/581232021-10-05 11:35:45.957metadata only accessoai:repositorio.unifesp.br:11600/58123Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652021-10-05T14:35:45Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review |
title |
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review |
spellingShingle |
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review Cerqueira, Raphael O. [UNIFESP] Vitex agnus castus Chasteberry Premenstrual syndrome Premenstrual dysphoric disorder Treatment |
title_short |
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review |
title_full |
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review |
title_fullStr |
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review |
title_full_unstemmed |
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review |
title_sort |
Vitex agnus castus for premenstrual syndrome and premenstrual dysphoric disorder: a systematic review |
author |
Cerqueira, Raphael O. [UNIFESP] |
author_facet |
Cerqueira, Raphael O. [UNIFESP] Frey, Benicio N. Leclerc, Emilie [UNIFESP] Brietzke, Elisa [UNIFESP] |
author_role |
author |
author2 |
Frey, Benicio N. Leclerc, Emilie [UNIFESP] Brietzke, Elisa [UNIFESP] |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Cerqueira, Raphael O. [UNIFESP] Frey, Benicio N. Leclerc, Emilie [UNIFESP] Brietzke, Elisa [UNIFESP] |
dc.subject.eng.fl_str_mv |
Vitex agnus castus Chasteberry Premenstrual syndrome Premenstrual dysphoric disorder Treatment |
topic |
Vitex agnus castus Chasteberry Premenstrual syndrome Premenstrual dysphoric disorder Treatment |
description |
The objective of this study was to evaluate whether Vitex agnus castus is a safe and effective treatment for PMS and premenstrual dysphoric disorder (PMDD) and to discuss the implications of these findings for clinical practice. A systematic review of literature was conducted using PubMed and Scielo databases. The inclusion criteria were randomized controlled trials (RCT) using V. agnus castus in individuals with PMS or PMDD that compared this intervention with placebo or an active comparator and included a description of blinding and dropouts/withdrawals. The search was conducted by two independent investigators who reached consensus on the included trials. A total of eight RCTs were included in this study. Most studies focused on PMS, and the diagnostic criteria of PMS and PMDD changed over the years. Three different preparations of V. agnus castus (VAC) were tested, and there was significant variability in the measurement of treatment outcomes between the studies. Nevertheless, all eight studies were positive for VAC in the treatment of PMS or PMDD and VAC was overall well tolerated. Main limitations were differences in definition of diagnostic criteria, the instruments used as main outcome measures, and different preparations of VAC extracts limit the comparison of results between studies. In conclusion, the RCTs using VAC for treatment of PMS/PMDD suggested that the VAC extract is a safe and efficacious alternative to be considered for the treatment of PMS/PMDD symptoms. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2020-09-01T13:21:12Z |
dc.date.available.fl_str_mv |
2020-09-01T13:21:12Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Archives Of Womens Mental Health. Wien, v. 20, n. 6, p. 713-719, 2017. |
dc.identifier.uri.fl_str_mv |
https://repositorio.unifesp.br/handle/11600/58123 http://dx.doi.org/10.1007/s00737-017-0791-0 |
dc.identifier.issn.none.fl_str_mv |
1434-1816 |
dc.identifier.doi.none.fl_str_mv |
10.1007/s00737-017-0791-0 |
dc.identifier.wos.none.fl_str_mv |
WOS:000415731700001 |
identifier_str_mv |
Archives Of Womens Mental Health. Wien, v. 20, n. 6, p. 713-719, 2017. 1434-1816 10.1007/s00737-017-0791-0 WOS:000415731700001 |
url |
https://repositorio.unifesp.br/handle/11600/58123 http://dx.doi.org/10.1007/s00737-017-0791-0 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.ispartof.none.fl_str_mv |
Archives Of Womens Mental Health |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
713-719 |
dc.coverage.none.fl_str_mv |
Wien |
dc.publisher.none.fl_str_mv |
Springer Wien |
publisher.none.fl_str_mv |
Springer Wien |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
|
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1802764138343038976 |