Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/29333 http://dx.doi.org/10.1016/j.seizure.2006.09.001 |
Resumo: | Objective: the objective of this retrospective study is to analyze ictal patterns observed during continuous Video-EEG monitoring in patients with temporal Lobe epilepsy (TLE) due to unilateral hippocampal sclerosis (HS), and to correlate these EEG patterns to temporal pole abnormalities observed on magnetic resonance imaging exams.Methods: We analyzed 147 seizures from 35 patients with TLE and unilateral HS. Ictal patterns were classified.,and correlated to signal abnormalities and volumetric measures of the temporal poles. Volume differences over 10% were considered abnormal.Results: the most frequent type of ictal pattern was rhythmic theta activity (RTA), encountered in 65.5% of the seizures. Rhythmic beta activity (RBA) was observed in 11% of the seizures, localized attenuation in 8%, interruption of epileptiform discharges in 6%, repetitive discharges in 5.5%, and rhythmic delta activity (RDA) in 4%. Sixty-six percent of the patients presented signal abnormalities in the temporal pole that were always ipsitateral to the HS. Sixty percent presented significant asymmetry of the temporal poles consisting of reduced volume that was also always ipsitateral to HS. Although patients with RTA as the predominant ictal pattern tended to present asymmetry of temporal poles (p = 0.305), the ictal EEG pattern did not correlate with temporal pole asymmetry or signal abnormalities.Conclusions: RTA is the most frequent initial ictal pattern inpatients with TLE due to unilateral HS. Temporal pole signal changes and volumetric reduction were commonly found in this group of patients, both abnormalities appearing always ipsitateral to the HS. However, neither temporal pole volume reduction nor signal abnormalities correlated with the predominant ictal pattern, suggesting that the temporal poles are not crucially involved in the process of epileptogenesis. (c) 2006 British Epilepsy Association. Published by Elsevier B.V. All rights reserved. |
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Caboclo, Luís Otávio Sales Ferreira [UNIFESP]Garzon, Eliana [UNIFESP]Oliveira, Pedro A. L.Carrete Junior, Henrique [UNIFESP]Centeno, Ricardo Silva [UNIFESP]Bianchin, Marino MuxfeldtYacubian, Elza Márcia Targas [UNIFESP]Sakamoto, Américo Ceiki [UNIFESP]Universidade de São Paulo (USP)Universidade Federal de São Paulo (UNIFESP)2016-01-24T12:41:41Z2016-01-24T12:41:41Z2007-01-01Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 16, n. 1, p. 8-16, 2007.1059-1311http://repositorio.unifesp.br/handle/11600/29333http://dx.doi.org/10.1016/j.seizure.2006.09.001WOS000243625700002.pdf10.1016/j.seizure.2006.09.001WOS:000243625700002Objective: the objective of this retrospective study is to analyze ictal patterns observed during continuous Video-EEG monitoring in patients with temporal Lobe epilepsy (TLE) due to unilateral hippocampal sclerosis (HS), and to correlate these EEG patterns to temporal pole abnormalities observed on magnetic resonance imaging exams.Methods: We analyzed 147 seizures from 35 patients with TLE and unilateral HS. Ictal patterns were classified.,and correlated to signal abnormalities and volumetric measures of the temporal poles. Volume differences over 10% were considered abnormal.Results: the most frequent type of ictal pattern was rhythmic theta activity (RTA), encountered in 65.5% of the seizures. Rhythmic beta activity (RBA) was observed in 11% of the seizures, localized attenuation in 8%, interruption of epileptiform discharges in 6%, repetitive discharges in 5.5%, and rhythmic delta activity (RDA) in 4%. Sixty-six percent of the patients presented signal abnormalities in the temporal pole that were always ipsitateral to the HS. Sixty percent presented significant asymmetry of the temporal poles consisting of reduced volume that was also always ipsitateral to HS. Although patients with RTA as the predominant ictal pattern tended to present asymmetry of temporal poles (p = 0.305), the ictal EEG pattern did not correlate with temporal pole asymmetry or signal abnormalities.Conclusions: RTA is the most frequent initial ictal pattern inpatients with TLE due to unilateral HS. Temporal pole signal changes and volumetric reduction were commonly found in this group of patients, both abnormalities appearing always ipsitateral to the HS. However, neither temporal pole volume reduction nor signal abnormalities correlated with the predominant ictal pattern, suggesting that the temporal poles are not crucially involved in the process of epileptogenesis. (c) 2006 British Epilepsy Association. Published by Elsevier B.V. All rights reserved.Univ São Paulo, Ribeirao Preto Sch Med, Dept Neurol Psychiat & Psychol, Div Neurol, BR-14048900 Ribeirao Preto, BrazilFed Univ São Paulo, Div Neurosurg, Dept Neurol & Neurosurg, São Paulo, BrazilFed Univ São Paulo, Div Neuroradiol, Dept Neurol & Neurosurg, São Paulo, BrazilFed Univ São Paulo, Div Neurol, Dept Neurol & Neurosurg, São Paulo, BrazilFed Univ São Paulo, Div Neurosurg, Dept Neurol & Neurosurg, São Paulo, BrazilFed Univ São Paulo, Div Neuroradiol, Dept Neurol & Neurosurg, São Paulo, BrazilFed Univ São Paulo, Div Neurol, Dept Neurol & Neurosurg, São Paulo, BrazilWeb of Science8-16engW B Saunders Co LtdSeizure-european Journal of Epilepsytemporal lobe epilepsyhippocampal sclerosisVideo-EEGEEG patternstemporal poleepilepsy surgeryCorrelation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000243625700002.pdfapplication/pdf429892${dspace.ui.url}/bitstream/11600/29333/1/WOS000243625700002.pdfe244cde9a7d577d8f30494f1ad6a23e9MD51open accessTEXTWOS000243625700002.pdf.txtWOS000243625700002.pdf.txtExtracted texttext/plain35856${dspace.ui.url}/bitstream/11600/29333/2/WOS000243625700002.pdf.txta4fcc36e44e871439ee8810d91d2cde2MD52open access11600/293332022-07-08 10:28:57.529open accessoai:repositorio.unifesp.br:11600/29333Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:18:02.148346Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy |
title |
Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy |
spellingShingle |
Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy Caboclo, Luís Otávio Sales Ferreira [UNIFESP] temporal lobe epilepsy hippocampal sclerosis Video-EEG EEG patterns temporal pole epilepsy surgery |
title_short |
Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy |
title_full |
Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy |
title_fullStr |
Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy |
title_full_unstemmed |
Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy |
title_sort |
Correlation between temporal pole MRI abnormalities and surface ictal EEG patterns in patients with unilateral mesial temporal lobe epilepsy |
author |
Caboclo, Luís Otávio Sales Ferreira [UNIFESP] |
author_facet |
Caboclo, Luís Otávio Sales Ferreira [UNIFESP] Garzon, Eliana [UNIFESP] Oliveira, Pedro A. L. Carrete Junior, Henrique [UNIFESP] Centeno, Ricardo Silva [UNIFESP] Bianchin, Marino Muxfeldt Yacubian, Elza Márcia Targas [UNIFESP] Sakamoto, Américo Ceiki [UNIFESP] |
author_role |
author |
author2 |
Garzon, Eliana [UNIFESP] Oliveira, Pedro A. L. Carrete Junior, Henrique [UNIFESP] Centeno, Ricardo Silva [UNIFESP] Bianchin, Marino Muxfeldt Yacubian, Elza Márcia Targas [UNIFESP] Sakamoto, Américo Ceiki [UNIFESP] |
author2_role |
author author author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Caboclo, Luís Otávio Sales Ferreira [UNIFESP] Garzon, Eliana [UNIFESP] Oliveira, Pedro A. L. Carrete Junior, Henrique [UNIFESP] Centeno, Ricardo Silva [UNIFESP] Bianchin, Marino Muxfeldt Yacubian, Elza Márcia Targas [UNIFESP] Sakamoto, Américo Ceiki [UNIFESP] |
dc.subject.eng.fl_str_mv |
temporal lobe epilepsy hippocampal sclerosis Video-EEG EEG patterns temporal pole epilepsy surgery |
topic |
temporal lobe epilepsy hippocampal sclerosis Video-EEG EEG patterns temporal pole epilepsy surgery |
description |
Objective: the objective of this retrospective study is to analyze ictal patterns observed during continuous Video-EEG monitoring in patients with temporal Lobe epilepsy (TLE) due to unilateral hippocampal sclerosis (HS), and to correlate these EEG patterns to temporal pole abnormalities observed on magnetic resonance imaging exams.Methods: We analyzed 147 seizures from 35 patients with TLE and unilateral HS. Ictal patterns were classified.,and correlated to signal abnormalities and volumetric measures of the temporal poles. Volume differences over 10% were considered abnormal.Results: the most frequent type of ictal pattern was rhythmic theta activity (RTA), encountered in 65.5% of the seizures. Rhythmic beta activity (RBA) was observed in 11% of the seizures, localized attenuation in 8%, interruption of epileptiform discharges in 6%, repetitive discharges in 5.5%, and rhythmic delta activity (RDA) in 4%. Sixty-six percent of the patients presented signal abnormalities in the temporal pole that were always ipsitateral to the HS. Sixty percent presented significant asymmetry of the temporal poles consisting of reduced volume that was also always ipsitateral to HS. Although patients with RTA as the predominant ictal pattern tended to present asymmetry of temporal poles (p = 0.305), the ictal EEG pattern did not correlate with temporal pole asymmetry or signal abnormalities.Conclusions: RTA is the most frequent initial ictal pattern inpatients with TLE due to unilateral HS. Temporal pole signal changes and volumetric reduction were commonly found in this group of patients, both abnormalities appearing always ipsitateral to the HS. However, neither temporal pole volume reduction nor signal abnormalities correlated with the predominant ictal pattern, suggesting that the temporal poles are not crucially involved in the process of epileptogenesis. (c) 2006 British Epilepsy Association. Published by Elsevier B.V. All rights reserved. |
publishDate |
2007 |
dc.date.issued.fl_str_mv |
2007-01-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T12:41:41Z |
dc.date.available.fl_str_mv |
2016-01-24T12:41:41Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 16, n. 1, p. 8-16, 2007. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/29333 http://dx.doi.org/10.1016/j.seizure.2006.09.001 |
dc.identifier.issn.none.fl_str_mv |
1059-1311 |
dc.identifier.file.none.fl_str_mv |
WOS000243625700002.pdf |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.seizure.2006.09.001 |
dc.identifier.wos.none.fl_str_mv |
WOS:000243625700002 |
identifier_str_mv |
Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 16, n. 1, p. 8-16, 2007. 1059-1311 WOS000243625700002.pdf 10.1016/j.seizure.2006.09.001 WOS:000243625700002 |
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http://repositorio.unifesp.br/handle/11600/29333 http://dx.doi.org/10.1016/j.seizure.2006.09.001 |
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eng |
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eng |
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Seizure-european Journal of Epilepsy |
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openAccess |
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8-16 |
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W B Saunders Co Ltd |
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W B Saunders Co Ltd |
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