Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates

Detalhes bibliográficos
Autor(a) principal: Quiles, Milene Gonçalves [UNIFESP]
Data de Publicação: 2015
Outros Autores: Rocchetti, Talita Trevisani [UNIFESP], Fehlberg, Lorena C. [UNIFESP], Kusano, E. J. U., Chebabo, A., Pereira, R. M. G., Gales, Ana Cristina [UNIFESP], Pignatari, Antonio Carlos Campos [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://repositorio.unifesp.br/handle/11600/38668
http://dx.doi.org/10.1590/1414-431X20144154
Resumo: We report the microbiological characterization of four New Delhi metallo-beta-lactamase-1 (bla(NDM-1))-producing Enterobacteriaceae isolated in Rio de Janeiro, Brazil. bla(NDM-1) was located on a conjugative plasmid and was associated with Klebsiella pneumoniae carbapenemase-2 (bla(KPC-2)) or aminoglycoside-resistance methylase ( armA), a 16S rRNA methylase not previously reported in Brazil, in two distinct strains of Enterobacter cloacae. Our results suggested that the introduction of bla(NDM-1) in Brazil has been accompanied by rapid spread, since our isolates showed no genetic relationship.
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spelling Quiles, Milene Gonçalves [UNIFESP]Rocchetti, Talita Trevisani [UNIFESP]Fehlberg, Lorena C. [UNIFESP]Kusano, E. J. U.Chebabo, A.Pereira, R. M. G.Gales, Ana Cristina [UNIFESP]Pignatari, Antonio Carlos Campos [UNIFESP]Universidade Federal de São Paulo (UNIFESP)DASA2016-01-24T14:39:57Z2016-01-24T14:39:57Z2015-02-01Brazilian Journal of Medical and Biological Research. São Paulo: Assoc Bras Divulg Cientifica, v. 48, n. 2, p. 174-177, 2015.0100-879Xhttp://repositorio.unifesp.br/handle/11600/38668http://dx.doi.org/10.1590/1414-431X20144154S0100-879X2015000200174.pdfS0100-879X201500020017410.1590/1414-431X20144154WOS:000351598300011We report the microbiological characterization of four New Delhi metallo-beta-lactamase-1 (bla(NDM-1))-producing Enterobacteriaceae isolated in Rio de Janeiro, Brazil. bla(NDM-1) was located on a conjugative plasmid and was associated with Klebsiella pneumoniae carbapenemase-2 (bla(KPC-2)) or aminoglycoside-resistance methylase ( armA), a 16S rRNA methylase not previously reported in Brazil, in two distinct strains of Enterobacter cloacae. Our results suggested that the introduction of bla(NDM-1) in Brazil has been accompanied by rapid spread, since our isolates showed no genetic relationship.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Federal de São Paulo, Dept Med, Lab Especial Microbiol Clin, São Paulo, SP, BrazilDASA, Lab Diagnost Amer, São Paulo, SP, BrazilUniversidade Federal de São Paulo, Dept Med, Lab Especial Microbiol Clin, São Paulo, SP, BrazilWeb of Science174-177engAssoc Bras Divulg CientificaBrazilian Journal of Medical and Biological ResearchEnterobacteriaceaeCarbapenem-resistanceCarbapenemasesMethylaseUnusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolatesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS0100-879X2015000200174.pdfapplication/pdf70887${dspace.ui.url}/bitstream/11600/38668/1/S0100-879X2015000200174.pdf7c8e34a5d65b610522668ce9db41588cMD51open access11600/386682023-02-15 11:39:38.05open accessoai:repositorio.unifesp.br:11600/38668Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-02-15T14:39:38Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.en.fl_str_mv Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates
title Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates
spellingShingle Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates
Quiles, Milene Gonçalves [UNIFESP]
Enterobacteriaceae
Carbapenem-resistance
Carbapenemases
Methylase
title_short Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates
title_full Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates
title_fullStr Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates
title_full_unstemmed Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates
title_sort Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates
author Quiles, Milene Gonçalves [UNIFESP]
author_facet Quiles, Milene Gonçalves [UNIFESP]
Rocchetti, Talita Trevisani [UNIFESP]
Fehlberg, Lorena C. [UNIFESP]
Kusano, E. J. U.
Chebabo, A.
Pereira, R. M. G.
Gales, Ana Cristina [UNIFESP]
Pignatari, Antonio Carlos Campos [UNIFESP]
author_role author
author2 Rocchetti, Talita Trevisani [UNIFESP]
Fehlberg, Lorena C. [UNIFESP]
Kusano, E. J. U.
Chebabo, A.
Pereira, R. M. G.
Gales, Ana Cristina [UNIFESP]
Pignatari, Antonio Carlos Campos [UNIFESP]
author2_role author
author
author
author
author
author
author
dc.contributor.institution.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
DASA
dc.contributor.author.fl_str_mv Quiles, Milene Gonçalves [UNIFESP]
Rocchetti, Talita Trevisani [UNIFESP]
Fehlberg, Lorena C. [UNIFESP]
Kusano, E. J. U.
Chebabo, A.
Pereira, R. M. G.
Gales, Ana Cristina [UNIFESP]
Pignatari, Antonio Carlos Campos [UNIFESP]
dc.subject.eng.fl_str_mv Enterobacteriaceae
Carbapenem-resistance
Carbapenemases
Methylase
topic Enterobacteriaceae
Carbapenem-resistance
Carbapenemases
Methylase
description We report the microbiological characterization of four New Delhi metallo-beta-lactamase-1 (bla(NDM-1))-producing Enterobacteriaceae isolated in Rio de Janeiro, Brazil. bla(NDM-1) was located on a conjugative plasmid and was associated with Klebsiella pneumoniae carbapenemase-2 (bla(KPC-2)) or aminoglycoside-resistance methylase ( armA), a 16S rRNA methylase not previously reported in Brazil, in two distinct strains of Enterobacter cloacae. Our results suggested that the introduction of bla(NDM-1) in Brazil has been accompanied by rapid spread, since our isolates showed no genetic relationship.
publishDate 2015
dc.date.issued.fl_str_mv 2015-02-01
dc.date.accessioned.fl_str_mv 2016-01-24T14:39:57Z
dc.date.available.fl_str_mv 2016-01-24T14:39:57Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv Brazilian Journal of Medical and Biological Research. São Paulo: Assoc Bras Divulg Cientifica, v. 48, n. 2, p. 174-177, 2015.
dc.identifier.uri.fl_str_mv http://repositorio.unifesp.br/handle/11600/38668
http://dx.doi.org/10.1590/1414-431X20144154
dc.identifier.issn.none.fl_str_mv 0100-879X
dc.identifier.file.none.fl_str_mv S0100-879X2015000200174.pdf
dc.identifier.scielo.none.fl_str_mv S0100-879X2015000200174
dc.identifier.doi.none.fl_str_mv 10.1590/1414-431X20144154
dc.identifier.wos.none.fl_str_mv WOS:000351598300011
identifier_str_mv Brazilian Journal of Medical and Biological Research. São Paulo: Assoc Bras Divulg Cientifica, v. 48, n. 2, p. 174-177, 2015.
0100-879X
S0100-879X2015000200174.pdf
S0100-879X2015000200174
10.1590/1414-431X20144154
WOS:000351598300011
url http://repositorio.unifesp.br/handle/11600/38668
http://dx.doi.org/10.1590/1414-431X20144154
dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.none.fl_str_mv Brazilian Journal of Medical and Biological Research
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 174-177
dc.publisher.none.fl_str_mv Assoc Bras Divulg Cientifica
publisher.none.fl_str_mv Assoc Bras Divulg Cientifica
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
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