Oral propranolol as a new treatment for facial infantile hemangioma: case report

Detalhes bibliográficos
Autor(a) principal: Ferreira, Rosane da Cruz [UNIFESP]
Data de Publicação: 2011
Outros Autores: Wolff, Francisco Romeu Locatelli, Morschbacher, Ricardo [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0004-27492011000300012
http://repositorio.unifesp.br/handle/11600/6479
Resumo: Hemangiomas are the most common benign tumors of infancy. Despite their self-limited course, infantile capillary hemangiomas can impair vital or sensory functions as vision and cause cosmetic deformity. The usual treatments include oral/intralesional steroids, alpha interferon, cytotoxins, pulsed dye laser and cosmetic surgery resection. These treatments are not free of multiple complications and toxic side effects. This report describes the case of a 3-month-old female baby with progressively increasing hemangioma of the left upper eyelid impinging over the visual field. The hemangioma promptly responded to low-dose oral propranolol. A clinical response was noticed few days after the beginning of the treatment, with regression to 1/4 of its original size in 45 days of treatment, and to less than 1/10 after 8 months, free of any major side effects.
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spelling Oral propranolol as a new treatment for facial infantile hemangioma: case reportPropranolol oral: novo tratamento para hemangioma facial em bebês: relato de casoHemangiomaHemangioma, capillaryPropranololCase reportsInfant, newbornHemangiomaHemangioma capilarPropranololRelato de casosRecém-nascidoHemangiomas are the most common benign tumors of infancy. Despite their self-limited course, infantile capillary hemangiomas can impair vital or sensory functions as vision and cause cosmetic deformity. The usual treatments include oral/intralesional steroids, alpha interferon, cytotoxins, pulsed dye laser and cosmetic surgery resection. These treatments are not free of multiple complications and toxic side effects. This report describes the case of a 3-month-old female baby with progressively increasing hemangioma of the left upper eyelid impinging over the visual field. The hemangioma promptly responded to low-dose oral propranolol. A clinical response was noticed few days after the beginning of the treatment, with regression to 1/4 of its original size in 45 days of treatment, and to less than 1/10 after 8 months, free of any major side effects.Hemangiomas são os tumores benignos mais comuns durante o primeiro ano de vida. Apesar do seu curso autolimitado, os hemangiomas capilares podem prejudicar funções vitais ou sensoriais como a visão e causar alteração estética. O tratamento usual inclui esteróides orais ou intralesionais, interferon alfa, citotoxinas, laser e ressecção cirúrgica. Entretanto estes tratamentos não estão livres de complicações e efeitos adversos. Este relato descreve o caso de um bebê feminino de 3 meses com um hemangioma rapidamente progressivo na pálpebra superior esquerda, causando obstrução no eixo visual. O hemangioma respondeu rapidamente a uma baixa dose oral de propranolol. A resposta clínica foi notada poucos dias após o início do tratamento, com regressão a 1/4 do seu tamanho original após 45 dias de tratamento, e a menos de 1/10 após 8 meses, sem ter apresentado nenhum efeito adverso.Federal University of São PauloPasso Fundo Hospital and Pronto Clínica HospitalSanta Casa de Misericórdia de Porto AlegreUNIFESPSciELOConselho Brasileiro de OftalmologiaUniversidade Federal de São Paulo (UNIFESP)Passo Fundo Hospital and Pronto Clínica HospitalSanta Casa de Misericórdia de Porto AlegreFerreira, Rosane da Cruz [UNIFESP]Wolff, Francisco Romeu LocatelliMorschbacher, Ricardo [UNIFESP]2015-06-14T13:43:06Z2015-06-14T13:43:06Z2011-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion207-208application/pdfhttp://dx.doi.org/10.1590/S0004-27492011000300012Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 74, n. 3, p. 207-208, 2011.10.1590/S0004-27492011000300012S0004-27492011000300012.pdf0004-2749S0004-27492011000300012http://repositorio.unifesp.br/handle/11600/6479engArquivos Brasileiros de Oftalmologiainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-05T02:49:51Zoai:repositorio.unifesp.br/:11600/6479Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-05T02:49:51Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Oral propranolol as a new treatment for facial infantile hemangioma: case report
Propranolol oral: novo tratamento para hemangioma facial em bebês: relato de caso
title Oral propranolol as a new treatment for facial infantile hemangioma: case report
spellingShingle Oral propranolol as a new treatment for facial infantile hemangioma: case report
Ferreira, Rosane da Cruz [UNIFESP]
Hemangioma
Hemangioma, capillary
Propranolol
Case reports
Infant, newborn
Hemangioma
Hemangioma capilar
Propranolol
Relato de casos
Recém-nascido
title_short Oral propranolol as a new treatment for facial infantile hemangioma: case report
title_full Oral propranolol as a new treatment for facial infantile hemangioma: case report
title_fullStr Oral propranolol as a new treatment for facial infantile hemangioma: case report
title_full_unstemmed Oral propranolol as a new treatment for facial infantile hemangioma: case report
title_sort Oral propranolol as a new treatment for facial infantile hemangioma: case report
author Ferreira, Rosane da Cruz [UNIFESP]
author_facet Ferreira, Rosane da Cruz [UNIFESP]
Wolff, Francisco Romeu Locatelli
Morschbacher, Ricardo [UNIFESP]
author_role author
author2 Wolff, Francisco Romeu Locatelli
Morschbacher, Ricardo [UNIFESP]
author2_role author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
Passo Fundo Hospital and Pronto Clínica Hospital
Santa Casa de Misericórdia de Porto Alegre
dc.contributor.author.fl_str_mv Ferreira, Rosane da Cruz [UNIFESP]
Wolff, Francisco Romeu Locatelli
Morschbacher, Ricardo [UNIFESP]
dc.subject.por.fl_str_mv Hemangioma
Hemangioma, capillary
Propranolol
Case reports
Infant, newborn
Hemangioma
Hemangioma capilar
Propranolol
Relato de casos
Recém-nascido
topic Hemangioma
Hemangioma, capillary
Propranolol
Case reports
Infant, newborn
Hemangioma
Hemangioma capilar
Propranolol
Relato de casos
Recém-nascido
description Hemangiomas are the most common benign tumors of infancy. Despite their self-limited course, infantile capillary hemangiomas can impair vital or sensory functions as vision and cause cosmetic deformity. The usual treatments include oral/intralesional steroids, alpha interferon, cytotoxins, pulsed dye laser and cosmetic surgery resection. These treatments are not free of multiple complications and toxic side effects. This report describes the case of a 3-month-old female baby with progressively increasing hemangioma of the left upper eyelid impinging over the visual field. The hemangioma promptly responded to low-dose oral propranolol. A clinical response was noticed few days after the beginning of the treatment, with regression to 1/4 of its original size in 45 days of treatment, and to less than 1/10 after 8 months, free of any major side effects.
publishDate 2011
dc.date.none.fl_str_mv 2011-06-01
2015-06-14T13:43:06Z
2015-06-14T13:43:06Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0004-27492011000300012
Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 74, n. 3, p. 207-208, 2011.
10.1590/S0004-27492011000300012
S0004-27492011000300012.pdf
0004-2749
S0004-27492011000300012
http://repositorio.unifesp.br/handle/11600/6479
url http://dx.doi.org/10.1590/S0004-27492011000300012
http://repositorio.unifesp.br/handle/11600/6479
identifier_str_mv Arquivos Brasileiros de Oftalmologia. Conselho Brasileiro de Oftalmologia, v. 74, n. 3, p. 207-208, 2011.
10.1590/S0004-27492011000300012
S0004-27492011000300012.pdf
0004-2749
S0004-27492011000300012
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Arquivos Brasileiros de Oftalmologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 207-208
application/pdf
dc.publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
publisher.none.fl_str_mv Conselho Brasileiro de Oftalmologia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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