O papel do adesivo de fibrina e da sutura na fixação do transplante de menisco preservado por ultracongelamento em coelhos

• Autor(a) principal: Reckers, Leandro José [UNIFESP]
• Data de Publicação: 2009
• Outros Autores: Fagundes, Djalma José [UNIFESP], Raymundo, José Luiz Pozo, Granata Júnior, Geraldo Sérgio De Mello [UNIFESP], Moreira, Márcia Bento [UNIFESP], Paiva, Vanessa Carla [UNIFESP], Fagundes, Anna Luiza Negrini, Cohen, Moises [UNIFESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1590/S0102-36162009000500005; http://repositorio.unifesp.br/handle/11600/5304
• topic: Meniscus; Transplantation; Rabbits; Fibrin tissue adhesive; Menisco; Transplante; Coelhos; Adesivo tecidual de fibrina

OBJECTIVE: To evaluate the ability of fibrin adhesive in promoting the meniscus fixation within two, four and eight weeks compared to the conventional soft-tissue suture technique. MATERIALS AND METHODS: 36 right medial menisci of rabbits preserved at negative 73° Celsius for 30 days were transplanted to animals of the same sample and fixed with soft-tissue suture or fibrin glue. After 2, 4 or 8 weeks, the appearance of the menisci and the quality of fixation were macroscopically checked and evaluated by a scoring system. The findings were subjected to the statistical study of variance analysis (p < 0.05%). RESULTS: The deep-frozen meniscus preservation maintained the integrity of the meniscus transplant, and, macroscopically, there was no significant reduction of the length of the meniscus in all post-transplant periods (p = 0.015). The menisci fixed with fibrin showed slight changes in color and surface roughness. There were no signs of rejection or infection in both groups. Suture fixation scoring was superior (p = 0.015) in all periods (80% of total fixation) as compared to the setting promoted by fibrin (20% of total fixation). CONCLUSION: The homologous transplantation of the meniscus of rabbits experienced various degrees of integration to the knee according to the fixation method; the surgical soft tissues suturing technique was shown to be superior in the evaluation of scores compared to the fixation with fibrin adhesive.