Aging histological changes in the cartilages of the cricoarytenoid joint

Detalhes bibliográficos
Autor(a) principal: Dedivitis, Rogério Aparecido [UNIFESP]
Data de Publicação: 2004
Outros Autores: Abrahão, Márcio [UNIFESP], Simões, Manuel de Jesus [UNIFESP], Mora, Oswaldo Alves [UNIFESP], Cervantes, Onivaldo [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/S0102-86502004000200010
http://repositorio.unifesp.br/handle/11600/2042
Resumo: PURPOSE: Analysis of ossification, bone marrow formation, perichondrium thickness, muscle fibers, collagen fibers and elastic fibers quantities of cricoid and arytenoid cartilages. Design: Correlation morphologic study. METHODS: Twenty-four cricoarytenoid joints were obtained from Caucasian male fresh cadavers divided into three groups with eight specimens in each: group I - adolescents, from 15 to 20; group II - adults, from 25 to 35; and group III - elderly, from 60 to 75. The specimens were stained with H-E; trichrome; Picrosirius; and elastic stain. Histometry was performed for quantitative analysis. Bonferroni Test, Fisher Test and the Variance Analysis were used. RESULTS: At the microscopic analysis, the group I specimens presented typical hyaline cartilage, thin perichondrium, bulky muscle fibers and were surrounded by collagen fibers. In group II, there were ossification in small well defined central areas of four specimens, with lamellar bone tissue. In two of these cases there were central bone cavity full of fat tissue. The other parameters were similar to group I. In group III, most part of hyaline cartilage was replaced by typical lamellar bone tissue with poorly outlined haversian systems. Hematopoietic tissue was noted in six cases and fat tissue in the other two. Perichondrium was thicker. Small muscle fibers were smaller and surrounded by collagen in great quantity. Elastic fibers were present in small quantity in the outer portion of perichondrium in all the groups. CONCLUSIONS: In spite of its lack in adolescence, ossification occurs in cricoid and arytenoid cartilages during adulthood and intensifies with age; bone marrow is formed in ossification tissue with hematopoietic tissue in group III; perichondrium becomes thicker in group III; muscle tissue atrophies in group III and is replaced by collagen fibers; these fibers thicken with age; and elastic fibers is always present in the perichondrium in low quantity.
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spelling Aging histological changes in the cartilages of the cricoarytenoid jointAlterações histológicas com a idade nas cartilagens da articulação cricoaritenóideaCricoid cartilageArytenoid cartilageAge groupsCadáverCartilagem cricóideCartilagem aritenóideGrupos etáriosCadáverPURPOSE: Analysis of ossification, bone marrow formation, perichondrium thickness, muscle fibers, collagen fibers and elastic fibers quantities of cricoid and arytenoid cartilages. Design: Correlation morphologic study. METHODS: Twenty-four cricoarytenoid joints were obtained from Caucasian male fresh cadavers divided into three groups with eight specimens in each: group I - adolescents, from 15 to 20; group II - adults, from 25 to 35; and group III - elderly, from 60 to 75. The specimens were stained with H-E; trichrome; Picrosirius; and elastic stain. Histometry was performed for quantitative analysis. Bonferroni Test, Fisher Test and the Variance Analysis were used. RESULTS: At the microscopic analysis, the group I specimens presented typical hyaline cartilage, thin perichondrium, bulky muscle fibers and were surrounded by collagen fibers. In group II, there were ossification in small well defined central areas of four specimens, with lamellar bone tissue. In two of these cases there were central bone cavity full of fat tissue. The other parameters were similar to group I. In group III, most part of hyaline cartilage was replaced by typical lamellar bone tissue with poorly outlined haversian systems. Hematopoietic tissue was noted in six cases and fat tissue in the other two. Perichondrium was thicker. Small muscle fibers were smaller and surrounded by collagen in great quantity. Elastic fibers were present in small quantity in the outer portion of perichondrium in all the groups. CONCLUSIONS: In spite of its lack in adolescence, ossification occurs in cricoid and arytenoid cartilages during adulthood and intensifies with age; bone marrow is formed in ossification tissue with hematopoietic tissue in group III; perichondrium becomes thicker in group III; muscle tissue atrophies in group III and is replaced by collagen fibers; these fibers thicken with age; and elastic fibers is always present in the perichondrium in low quantity.OBJETIVO: Análise da ossificação, formação de medula óssea, espessura do pericôndrio, da quantidade de fibras musculares, de colágeno e eláticas das cartilagens cricóidea e aritenóidea. Desenho: Estudo morfológico comparativo. MÉTODOS: Vinte e quatro articulações crico-aritenóideas foram obtidas de cadáveres frescos caucasianos masculinos, divididos em três grupos com oito espécimes cada: grupo I - adolescentes, de 15 a 20 anos; grupo II - adultos, de 25 a 35; e grupo III - idosos, de 60 a 75. Os espécimes foram corados com H.E.; tricrômio; Picrosirius; e coloração para fibras elásticas. Histometria foi realizada para a análise quantitativa. Teste de Bonferroni, Teste Exato de Fisher e a Análise de Variância foram utilizados. RESULTADOS: À análise microscópica, os espécimes do grupo I apresentaram cartilagem hialina típica, pericôndrio fino, fibras musculares espessas e cercadas por colágeno em pequena quantidade. No grupo II, havia ossificação em pequenas áreas centrais bem definidas em quatro espécimes, com tecido ósseo lamelar. Em dois desses casos, havia uma cavidade óssea central preenchida por tecido adiposo. Os demais parâmetros foram similares ao grupo I. No grupo III, a maior parte da cartilagem hialina estava substituída por típico tecido ósseo lamelar com sistemas de Havers. Tecido hematopoiético foi observado em seis casos e tecido adiposo nos outros dois. O pericôndrio estava espesso. As fibras musculares estavam menores e cercadas por colágeno em grande quantidade. Fibras elásticas estavam presentes em pequena quantidade na porção externa do pericôndrio em todos os grupos. CONCLUSÕES: Apesar de sua ausência na adolescência, a ossificação occorreu nas cartilagens cricóidea e aritenóidea durante a idade adulta e intensificou-se com a idade; medula óssea é formada no tecido de ossificação com tecido hematopoiético no grupo III; o pericôndrio tornou-se espesso no grupo III; as fibras musculares atrofiaram no grupo III e foram substituídas por fibras de colágeno; estas fibras espessaram-se com a idade; e as fibras elásticas estavam sempre presentes no pericôndrio em pequena quantidade.UNIFESP-EPMUNIMESUNIFESP, EPMSciELOSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaUniversidade Federal de São Paulo (UNIFESP)UNIMESDedivitis, Rogério Aparecido [UNIFESP]Abrahão, Márcio [UNIFESP]Simões, Manuel de Jesus [UNIFESP]Mora, Oswaldo Alves [UNIFESP]Cervantes, Onivaldo [UNIFESP]2015-06-14T13:30:20Z2015-06-14T13:30:20Z2004-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion136-140application/pdfhttp://dx.doi.org/10.1590/S0102-86502004000200010Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 19, n. 2, p. 136-140, 2004.10.1590/S0102-86502004000200010S0102-86502004000200010.pdf0102-8650S0102-86502004000200010http://repositorio.unifesp.br/handle/11600/2042engActa Cirurgica Brasileirainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-06T01:30:10Zoai:repositorio.unifesp.br/:11600/2042Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-06T01:30:10Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Aging histological changes in the cartilages of the cricoarytenoid joint
Alterações histológicas com a idade nas cartilagens da articulação cricoaritenóidea
title Aging histological changes in the cartilages of the cricoarytenoid joint
spellingShingle Aging histological changes in the cartilages of the cricoarytenoid joint
Dedivitis, Rogério Aparecido [UNIFESP]
Cricoid cartilage
Arytenoid cartilage
Age groups
Cadáver
Cartilagem cricóide
Cartilagem aritenóide
Grupos etários
Cadáver
title_short Aging histological changes in the cartilages of the cricoarytenoid joint
title_full Aging histological changes in the cartilages of the cricoarytenoid joint
title_fullStr Aging histological changes in the cartilages of the cricoarytenoid joint
title_full_unstemmed Aging histological changes in the cartilages of the cricoarytenoid joint
title_sort Aging histological changes in the cartilages of the cricoarytenoid joint
author Dedivitis, Rogério Aparecido [UNIFESP]
author_facet Dedivitis, Rogério Aparecido [UNIFESP]
Abrahão, Márcio [UNIFESP]
Simões, Manuel de Jesus [UNIFESP]
Mora, Oswaldo Alves [UNIFESP]
Cervantes, Onivaldo [UNIFESP]
author_role author
author2 Abrahão, Márcio [UNIFESP]
Simões, Manuel de Jesus [UNIFESP]
Mora, Oswaldo Alves [UNIFESP]
Cervantes, Onivaldo [UNIFESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
UNIMES
dc.contributor.author.fl_str_mv Dedivitis, Rogério Aparecido [UNIFESP]
Abrahão, Márcio [UNIFESP]
Simões, Manuel de Jesus [UNIFESP]
Mora, Oswaldo Alves [UNIFESP]
Cervantes, Onivaldo [UNIFESP]
dc.subject.por.fl_str_mv Cricoid cartilage
Arytenoid cartilage
Age groups
Cadáver
Cartilagem cricóide
Cartilagem aritenóide
Grupos etários
Cadáver
topic Cricoid cartilage
Arytenoid cartilage
Age groups
Cadáver
Cartilagem cricóide
Cartilagem aritenóide
Grupos etários
Cadáver
description PURPOSE: Analysis of ossification, bone marrow formation, perichondrium thickness, muscle fibers, collagen fibers and elastic fibers quantities of cricoid and arytenoid cartilages. Design: Correlation morphologic study. METHODS: Twenty-four cricoarytenoid joints were obtained from Caucasian male fresh cadavers divided into three groups with eight specimens in each: group I - adolescents, from 15 to 20; group II - adults, from 25 to 35; and group III - elderly, from 60 to 75. The specimens were stained with H-E; trichrome; Picrosirius; and elastic stain. Histometry was performed for quantitative analysis. Bonferroni Test, Fisher Test and the Variance Analysis were used. RESULTS: At the microscopic analysis, the group I specimens presented typical hyaline cartilage, thin perichondrium, bulky muscle fibers and were surrounded by collagen fibers. In group II, there were ossification in small well defined central areas of four specimens, with lamellar bone tissue. In two of these cases there were central bone cavity full of fat tissue. The other parameters were similar to group I. In group III, most part of hyaline cartilage was replaced by typical lamellar bone tissue with poorly outlined haversian systems. Hematopoietic tissue was noted in six cases and fat tissue in the other two. Perichondrium was thicker. Small muscle fibers were smaller and surrounded by collagen in great quantity. Elastic fibers were present in small quantity in the outer portion of perichondrium in all the groups. CONCLUSIONS: In spite of its lack in adolescence, ossification occurs in cricoid and arytenoid cartilages during adulthood and intensifies with age; bone marrow is formed in ossification tissue with hematopoietic tissue in group III; perichondrium becomes thicker in group III; muscle tissue atrophies in group III and is replaced by collagen fibers; these fibers thicken with age; and elastic fibers is always present in the perichondrium in low quantity.
publishDate 2004
dc.date.none.fl_str_mv 2004-04-01
2015-06-14T13:30:20Z
2015-06-14T13:30:20Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S0102-86502004000200010
Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 19, n. 2, p. 136-140, 2004.
10.1590/S0102-86502004000200010
S0102-86502004000200010.pdf
0102-8650
S0102-86502004000200010
http://repositorio.unifesp.br/handle/11600/2042
url http://dx.doi.org/10.1590/S0102-86502004000200010
http://repositorio.unifesp.br/handle/11600/2042
identifier_str_mv Acta Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 19, n. 2, p. 136-140, 2004.
10.1590/S0102-86502004000200010
S0102-86502004000200010.pdf
0102-8650
S0102-86502004000200010
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Acta Cirurgica Brasileira
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 136-140
application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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