Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign

Detalhes bibliográficos
Autor(a) principal: Marcos, Ana Carolina Cavalcanti [UNIFESP]
Data de Publicação: 2012
Outros Autores: Pelissoni, Fernanda D'angelo Monteiro [UNIFESP], Cunegundes, Kelly Simone Almeida [UNIFESP], Abramczyk, Marcelo Luiz [UNIFESP], Bellei, Nancy Cristina Junqueira [UNIFESP], Sanches, Nivea Aparecida Pissaia [UNIFESP], De Moraes-Pinto, Maria Isabel [UNIFESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.6061/clinics/2012(10)15
http://repositorio.unifesp.br/handle/11600/7340
Resumo: lIn 2009, the influenza A (H1N1) virus spread rapidly around the world, causing the first pandemic of the 21st Century. In 2010, there was a vaccination campaign against this new virus subtype to reduce the morbidity and mortality of the disease in some countries, including Brazil. Herein, we describe the clinical and epidemiological characteristics of patients under 19 years of age who were hospitalized with confirmed influenza A (H1N1) infection in 2009 and 2010. We retrospectively reviewed files from the pediatric patients who were admitted to a university hospital with real-time polymerase chain reaction (RT-PCR) confirmed influenza A (H1N1) infection in 2009 and 2010. There were 37 hospitalized patients with influenza A (H1N1) in 2009 and 2 in 2010. In 2009, many of the hospitalized children had an underlying chronic disease and a lower median age than those not hospitalized. Of the hospitalized patients, 78% had a chronic disease, primarily pneumopathy (48%). The main signs and symptoms of influenza were fever (97%), cough (76%), and dyspnea (59%). Complications occurred in 81% of the patients. The median length of hospitalization was five days; 27% of the patients required intensive care, and two died. In 2010, two patients were hospitalized with influenza A (H1N1): one infant with adenovirus co-infection who had received one previous H1N1 vaccine dose and presented with respiratory sequelae and a 2-month-old infant who had a hospital-acquired infection. An impressive reduction in hospital admissions was observed in 2010 when the vaccination campaign took place in Brazil.
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spelling Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaignInfluenza A VirusH1N1 SubtypeChronic DiseaselIn 2009, the influenza A (H1N1) virus spread rapidly around the world, causing the first pandemic of the 21st Century. In 2010, there was a vaccination campaign against this new virus subtype to reduce the morbidity and mortality of the disease in some countries, including Brazil. Herein, we describe the clinical and epidemiological characteristics of patients under 19 years of age who were hospitalized with confirmed influenza A (H1N1) infection in 2009 and 2010. We retrospectively reviewed files from the pediatric patients who were admitted to a university hospital with real-time polymerase chain reaction (RT-PCR) confirmed influenza A (H1N1) infection in 2009 and 2010. There were 37 hospitalized patients with influenza A (H1N1) in 2009 and 2 in 2010. In 2009, many of the hospitalized children had an underlying chronic disease and a lower median age than those not hospitalized. Of the hospitalized patients, 78% had a chronic disease, primarily pneumopathy (48%). The main signs and symptoms of influenza were fever (97%), cough (76%), and dyspnea (59%). Complications occurred in 81% of the patients. The median length of hospitalization was five days; 27% of the patients required intensive care, and two died. In 2010, two patients were hospitalized with influenza A (H1N1): one infant with adenovirus co-infection who had received one previous H1N1 vaccine dose and presented with respiratory sequelae and a 2-month-old infant who had a hospital-acquired infection. An impressive reduction in hospital admissions was observed in 2010 when the vaccination campaign took place in Brazil.Federal University of São Paulo Department of Pediatrics Division of Pediatric Infectious DiseasesFederal University of São Paulo Department of Medicine Infectious Disease UnitFederal University of São Paulo Department of Preventive MedicineUNIFESP, Department of Pediatrics Division of Pediatric Infectious DiseasesUNIFESP, Department of Medicine Infectious Disease UnitUNIFESP, Department of Preventive MedicineSciELOFaculdade de Medicina / USPUniversidade Federal de São Paulo (UNIFESP)Marcos, Ana Carolina Cavalcanti [UNIFESP]Pelissoni, Fernanda D'angelo Monteiro [UNIFESP]Cunegundes, Kelly Simone Almeida [UNIFESP]Abramczyk, Marcelo Luiz [UNIFESP]Bellei, Nancy Cristina Junqueira [UNIFESP]Sanches, Nivea Aparecida Pissaia [UNIFESP]De Moraes-Pinto, Maria Isabel [UNIFESP]2015-06-14T13:44:59Z2015-06-14T13:44:59Z2012-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion1215-1218application/pdfhttp://dx.doi.org/10.6061/clinics/2012(10)15Clinics. Faculdade de Medicina / USP, v. 67, n. 10, p. 1215-1218, 2012.10.6061/clinics/2012(10)15S1807-59322012001000015.pdf1807-5932S1807-59322012001000015http://repositorio.unifesp.br/handle/11600/7340WOS:000309938100015engClinicsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-07-28T04:40:49Zoai:repositorio.unifesp.br/:11600/7340Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-07-28T04:40:49Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign
title Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign
spellingShingle Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign
Marcos, Ana Carolina Cavalcanti [UNIFESP]
Influenza A Virus
H1N1 Subtype
Chronic Disease
title_short Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign
title_full Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign
title_fullStr Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign
title_full_unstemmed Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign
title_sort Pediatric hospital admissions from influenza A (H1N1) in Brazil: effects of the 2010 vaccination campaign
author Marcos, Ana Carolina Cavalcanti [UNIFESP]
author_facet Marcos, Ana Carolina Cavalcanti [UNIFESP]
Pelissoni, Fernanda D'angelo Monteiro [UNIFESP]
Cunegundes, Kelly Simone Almeida [UNIFESP]
Abramczyk, Marcelo Luiz [UNIFESP]
Bellei, Nancy Cristina Junqueira [UNIFESP]
Sanches, Nivea Aparecida Pissaia [UNIFESP]
De Moraes-Pinto, Maria Isabel [UNIFESP]
author_role author
author2 Pelissoni, Fernanda D'angelo Monteiro [UNIFESP]
Cunegundes, Kelly Simone Almeida [UNIFESP]
Abramczyk, Marcelo Luiz [UNIFESP]
Bellei, Nancy Cristina Junqueira [UNIFESP]
Sanches, Nivea Aparecida Pissaia [UNIFESP]
De Moraes-Pinto, Maria Isabel [UNIFESP]
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Federal de São Paulo (UNIFESP)
dc.contributor.author.fl_str_mv Marcos, Ana Carolina Cavalcanti [UNIFESP]
Pelissoni, Fernanda D'angelo Monteiro [UNIFESP]
Cunegundes, Kelly Simone Almeida [UNIFESP]
Abramczyk, Marcelo Luiz [UNIFESP]
Bellei, Nancy Cristina Junqueira [UNIFESP]
Sanches, Nivea Aparecida Pissaia [UNIFESP]
De Moraes-Pinto, Maria Isabel [UNIFESP]
dc.subject.por.fl_str_mv Influenza A Virus
H1N1 Subtype
Chronic Disease
topic Influenza A Virus
H1N1 Subtype
Chronic Disease
description lIn 2009, the influenza A (H1N1) virus spread rapidly around the world, causing the first pandemic of the 21st Century. In 2010, there was a vaccination campaign against this new virus subtype to reduce the morbidity and mortality of the disease in some countries, including Brazil. Herein, we describe the clinical and epidemiological characteristics of patients under 19 years of age who were hospitalized with confirmed influenza A (H1N1) infection in 2009 and 2010. We retrospectively reviewed files from the pediatric patients who were admitted to a university hospital with real-time polymerase chain reaction (RT-PCR) confirmed influenza A (H1N1) infection in 2009 and 2010. There were 37 hospitalized patients with influenza A (H1N1) in 2009 and 2 in 2010. In 2009, many of the hospitalized children had an underlying chronic disease and a lower median age than those not hospitalized. Of the hospitalized patients, 78% had a chronic disease, primarily pneumopathy (48%). The main signs and symptoms of influenza were fever (97%), cough (76%), and dyspnea (59%). Complications occurred in 81% of the patients. The median length of hospitalization was five days; 27% of the patients required intensive care, and two died. In 2010, two patients were hospitalized with influenza A (H1N1): one infant with adenovirus co-infection who had received one previous H1N1 vaccine dose and presented with respiratory sequelae and a 2-month-old infant who had a hospital-acquired infection. An impressive reduction in hospital admissions was observed in 2010 when the vaccination campaign took place in Brazil.
publishDate 2012
dc.date.none.fl_str_mv 2012-10-01
2015-06-14T13:44:59Z
2015-06-14T13:44:59Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.6061/clinics/2012(10)15
Clinics. Faculdade de Medicina / USP, v. 67, n. 10, p. 1215-1218, 2012.
10.6061/clinics/2012(10)15
S1807-59322012001000015.pdf
1807-5932
S1807-59322012001000015
http://repositorio.unifesp.br/handle/11600/7340
WOS:000309938100015
url http://dx.doi.org/10.6061/clinics/2012(10)15
http://repositorio.unifesp.br/handle/11600/7340
identifier_str_mv Clinics. Faculdade de Medicina / USP, v. 67, n. 10, p. 1215-1218, 2012.
10.6061/clinics/2012(10)15
S1807-59322012001000015.pdf
1807-5932
S1807-59322012001000015
WOS:000309938100015
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Clinics
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1215-1218
application/pdf
dc.publisher.none.fl_str_mv Faculdade de Medicina / USP
publisher.none.fl_str_mv Faculdade de Medicina / USP
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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