Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice

Detalhes bibliográficos
Autor(a) principal: Salum, Giovanni Abrahao
Data de Publicação: 2013
Outros Autores: DeSousa, Diogo Araujo, Rosario, Maria Conceicao do [UNIFESP], Pine, Daniel Samuel, Manfro, Gisele Gus
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNIFESP
Texto Completo: http://dx.doi.org/10.1590/1516-4446-2013-S108
http://repositorio.unifesp.br/handle/11600/35725
Resumo: The objective of this narrative review of the literature is to describe the epidemiology, etiology, pathophysiology, diagnosis, and treatment of pediatric anxiety disorders. We aim to guide clinicians in understanding the biology of anxiety disorders and to provide general guidelines for the proper diagnoses and treatment of these conditions early in life. Anxiety disorders are prevalent, associated with a number of negative life outcomes, and currently under-recognized and under-treated. the etiology involves both genes and environmental influences modifying the neural substrate in a complex interplay. Research on pathophysiology is still in its infancy, but some brain regions, such as the amygdala and the prefrontal cortex, have been implicated in fear and anxiety. Current practice is to establish diagnosis based purely on clinical features, derived from clinical interviews with the child, parents, and teachers. Treatment is effective using medication, cognitive behavioral therapy, or a combination of both. An introduction to the neuroscience behind anxiety disorders combined with an evidence-based approach may help clinicians to understand these disorders and treat them properly in childhood.
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spelling Pediatric anxiety disorders: from neuroscience to evidence-based clinical practiceChildadolescentanxiety disordersobsessive-compulsive disorderThe objective of this narrative review of the literature is to describe the epidemiology, etiology, pathophysiology, diagnosis, and treatment of pediatric anxiety disorders. We aim to guide clinicians in understanding the biology of anxiety disorders and to provide general guidelines for the proper diagnoses and treatment of these conditions early in life. Anxiety disorders are prevalent, associated with a number of negative life outcomes, and currently under-recognized and under-treated. the etiology involves both genes and environmental influences modifying the neural substrate in a complex interplay. Research on pathophysiology is still in its infancy, but some brain regions, such as the amygdala and the prefrontal cortex, have been implicated in fear and anxiety. Current practice is to establish diagnosis based purely on clinical features, derived from clinical interviews with the child, parents, and teachers. Treatment is effective using medication, cognitive behavioral therapy, or a combination of both. An introduction to the neuroscience behind anxiety disorders combined with an evidence-based approach may help clinicians to understand these disorders and treat them properly in childhood.Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Anxiety Disorders Outpatient Program Child & Adol, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Grad Program Med Sci Psychiat, Porto Alegre, RS, BrazilConselho Nacl Desenvolvimento Cientif & Tecnol CN, Natl Sci & Technol Inst Dev Psychiat Children & A, São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Dept Psychiat, Child & Adolescent Psychiat Unit, São Paulo, BrazilNIMH, Intramural Res Program Emot & Dev Branch, Bethesda, MD 20892 USAUniversidade Federal de São Paulo UNIFESP, Dept Psychiat, Child & Adolescent Psychiat Unit, São Paulo, BrazilWeb of ScienceCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundacao de Amparo a Pesquisa do Estado do Rio Grande do Sul (FAPERGS)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FAPERGSFundo de Incentivo a Pesquisa - Hospital de Clinicas de Porto Alegre - FIPE-HCPAAssoc Brasileira PsiquiatriaUniv Fed Rio Grande do SulConselho Nacl Desenvolvimento Cientif & Tecnol CNUniversidade Federal de São Paulo (UNIFESP)NIMHSalum, Giovanni AbrahaoDeSousa, Diogo AraujoRosario, Maria Conceicao do [UNIFESP]Pine, Daniel SamuelManfro, Gisele Gus2016-01-24T14:30:56Z2016-01-24T14:30:56Z2013-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionS3-S21application/pdfhttp://dx.doi.org/10.1590/1516-4446-2013-S108Revista Brasileira de Psiquiatria. São Paulo: Assoc Brasileira Psiquiatria, v. 35, p. S3-S21, 2013.10.1590/1516-4446-2013-S108S1516-44462013000500003.pdf1516-4446S1516-44462013000500003http://repositorio.unifesp.br/handle/11600/35725WOS:000325742100003engRevista Brasileira de Psiquiatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-01T04:27:48Zoai:repositorio.unifesp.br/:11600/35725Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-01T04:27:48Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false
dc.title.none.fl_str_mv Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
title Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
spellingShingle Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
Salum, Giovanni Abrahao
Child
adolescent
anxiety disorders
obsessive-compulsive disorder
title_short Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
title_full Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
title_fullStr Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
title_full_unstemmed Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
title_sort Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
author Salum, Giovanni Abrahao
author_facet Salum, Giovanni Abrahao
DeSousa, Diogo Araujo
Rosario, Maria Conceicao do [UNIFESP]
Pine, Daniel Samuel
Manfro, Gisele Gus
author_role author
author2 DeSousa, Diogo Araujo
Rosario, Maria Conceicao do [UNIFESP]
Pine, Daniel Samuel
Manfro, Gisele Gus
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Univ Fed Rio Grande do Sul
Conselho Nacl Desenvolvimento Cientif & Tecnol CN
Universidade Federal de São Paulo (UNIFESP)
NIMH
dc.contributor.author.fl_str_mv Salum, Giovanni Abrahao
DeSousa, Diogo Araujo
Rosario, Maria Conceicao do [UNIFESP]
Pine, Daniel Samuel
Manfro, Gisele Gus
dc.subject.por.fl_str_mv Child
adolescent
anxiety disorders
obsessive-compulsive disorder
topic Child
adolescent
anxiety disorders
obsessive-compulsive disorder
description The objective of this narrative review of the literature is to describe the epidemiology, etiology, pathophysiology, diagnosis, and treatment of pediatric anxiety disorders. We aim to guide clinicians in understanding the biology of anxiety disorders and to provide general guidelines for the proper diagnoses and treatment of these conditions early in life. Anxiety disorders are prevalent, associated with a number of negative life outcomes, and currently under-recognized and under-treated. the etiology involves both genes and environmental influences modifying the neural substrate in a complex interplay. Research on pathophysiology is still in its infancy, but some brain regions, such as the amygdala and the prefrontal cortex, have been implicated in fear and anxiety. Current practice is to establish diagnosis based purely on clinical features, derived from clinical interviews with the child, parents, and teachers. Treatment is effective using medication, cognitive behavioral therapy, or a combination of both. An introduction to the neuroscience behind anxiety disorders combined with an evidence-based approach may help clinicians to understand these disorders and treat them properly in childhood.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
2016-01-24T14:30:56Z
2016-01-24T14:30:56Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/1516-4446-2013-S108
Revista Brasileira de Psiquiatria. São Paulo: Assoc Brasileira Psiquiatria, v. 35, p. S3-S21, 2013.
10.1590/1516-4446-2013-S108
S1516-44462013000500003.pdf
1516-4446
S1516-44462013000500003
http://repositorio.unifesp.br/handle/11600/35725
WOS:000325742100003
url http://dx.doi.org/10.1590/1516-4446-2013-S108
http://repositorio.unifesp.br/handle/11600/35725
identifier_str_mv Revista Brasileira de Psiquiatria. São Paulo: Assoc Brasileira Psiquiatria, v. 35, p. S3-S21, 2013.
10.1590/1516-4446-2013-S108
S1516-44462013000500003.pdf
1516-4446
S1516-44462013000500003
WOS:000325742100003
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Revista Brasileira de Psiquiatria
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv S3-S21
application/pdf
dc.publisher.none.fl_str_mv Assoc Brasileira Psiquiatria
publisher.none.fl_str_mv Assoc Brasileira Psiquiatria
dc.source.none.fl_str_mv reponame:Repositório Institucional da UNIFESP
instname:Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
instname_str Universidade Federal de São Paulo (UNIFESP)
instacron_str UNIFESP
institution UNIFESP
reponame_str Repositório Institucional da UNIFESP
collection Repositório Institucional da UNIFESP
repository.name.fl_str_mv Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)
repository.mail.fl_str_mv biblioteca.csp@unifesp.br
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