Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://dx.doi.org/10.1590/1516-4446-2013-S108 http://repositorio.unifesp.br/handle/11600/35725 |
Resumo: | The objective of this narrative review of the literature is to describe the epidemiology, etiology, pathophysiology, diagnosis, and treatment of pediatric anxiety disorders. We aim to guide clinicians in understanding the biology of anxiety disorders and to provide general guidelines for the proper diagnoses and treatment of these conditions early in life. Anxiety disorders are prevalent, associated with a number of negative life outcomes, and currently under-recognized and under-treated. the etiology involves both genes and environmental influences modifying the neural substrate in a complex interplay. Research on pathophysiology is still in its infancy, but some brain regions, such as the amygdala and the prefrontal cortex, have been implicated in fear and anxiety. Current practice is to establish diagnosis based purely on clinical features, derived from clinical interviews with the child, parents, and teachers. Treatment is effective using medication, cognitive behavioral therapy, or a combination of both. An introduction to the neuroscience behind anxiety disorders combined with an evidence-based approach may help clinicians to understand these disorders and treat them properly in childhood. |
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Pediatric anxiety disorders: from neuroscience to evidence-based clinical practiceChildadolescentanxiety disordersobsessive-compulsive disorderThe objective of this narrative review of the literature is to describe the epidemiology, etiology, pathophysiology, diagnosis, and treatment of pediatric anxiety disorders. We aim to guide clinicians in understanding the biology of anxiety disorders and to provide general guidelines for the proper diagnoses and treatment of these conditions early in life. Anxiety disorders are prevalent, associated with a number of negative life outcomes, and currently under-recognized and under-treated. the etiology involves both genes and environmental influences modifying the neural substrate in a complex interplay. Research on pathophysiology is still in its infancy, but some brain regions, such as the amygdala and the prefrontal cortex, have been implicated in fear and anxiety. Current practice is to establish diagnosis based purely on clinical features, derived from clinical interviews with the child, parents, and teachers. Treatment is effective using medication, cognitive behavioral therapy, or a combination of both. An introduction to the neuroscience behind anxiety disorders combined with an evidence-based approach may help clinicians to understand these disorders and treat them properly in childhood.Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Anxiety Disorders Outpatient Program Child & Adol, Porto Alegre, RS, BrazilUniv Fed Rio Grande do Sul, Grad Program Med Sci Psychiat, Porto Alegre, RS, BrazilConselho Nacl Desenvolvimento Cientif & Tecnol CN, Natl Sci & Technol Inst Dev Psychiat Children & A, São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Dept Psychiat, Child & Adolescent Psychiat Unit, São Paulo, BrazilNIMH, Intramural Res Program Emot & Dev Branch, Bethesda, MD 20892 USAUniversidade Federal de São Paulo UNIFESP, Dept Psychiat, Child & Adolescent Psychiat Unit, São Paulo, BrazilWeb of ScienceCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundacao de Amparo a Pesquisa do Estado do Rio Grande do Sul (FAPERGS)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FAPERGSFundo de Incentivo a Pesquisa - Hospital de Clinicas de Porto Alegre - FIPE-HCPAAssoc Brasileira PsiquiatriaUniv Fed Rio Grande do SulConselho Nacl Desenvolvimento Cientif & Tecnol CNUniversidade Federal de São Paulo (UNIFESP)NIMHSalum, Giovanni AbrahaoDeSousa, Diogo AraujoRosario, Maria Conceicao do [UNIFESP]Pine, Daniel SamuelManfro, Gisele Gus2016-01-24T14:30:56Z2016-01-24T14:30:56Z2013-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionS3-S21application/pdfhttp://dx.doi.org/10.1590/1516-4446-2013-S108Revista Brasileira de Psiquiatria. São Paulo: Assoc Brasileira Psiquiatria, v. 35, p. S3-S21, 2013.10.1590/1516-4446-2013-S108S1516-44462013000500003.pdf1516-4446S1516-44462013000500003http://repositorio.unifesp.br/handle/11600/35725WOS:000325742100003engRevista Brasileira de Psiquiatriainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESP2024-08-01T04:27:48Zoai:repositorio.unifesp.br/:11600/35725Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestbiblioteca.csp@unifesp.bropendoar:34652024-08-01T04:27:48Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.none.fl_str_mv |
Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice |
title |
Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice |
spellingShingle |
Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice Salum, Giovanni Abrahao Child adolescent anxiety disorders obsessive-compulsive disorder |
title_short |
Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice |
title_full |
Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice |
title_fullStr |
Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice |
title_full_unstemmed |
Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice |
title_sort |
Pediatric anxiety disorders: from neuroscience to evidence-based clinical practice |
author |
Salum, Giovanni Abrahao |
author_facet |
Salum, Giovanni Abrahao DeSousa, Diogo Araujo Rosario, Maria Conceicao do [UNIFESP] Pine, Daniel Samuel Manfro, Gisele Gus |
author_role |
author |
author2 |
DeSousa, Diogo Araujo Rosario, Maria Conceicao do [UNIFESP] Pine, Daniel Samuel Manfro, Gisele Gus |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Univ Fed Rio Grande do Sul Conselho Nacl Desenvolvimento Cientif & Tecnol CN Universidade Federal de São Paulo (UNIFESP) NIMH |
dc.contributor.author.fl_str_mv |
Salum, Giovanni Abrahao DeSousa, Diogo Araujo Rosario, Maria Conceicao do [UNIFESP] Pine, Daniel Samuel Manfro, Gisele Gus |
dc.subject.por.fl_str_mv |
Child adolescent anxiety disorders obsessive-compulsive disorder |
topic |
Child adolescent anxiety disorders obsessive-compulsive disorder |
description |
The objective of this narrative review of the literature is to describe the epidemiology, etiology, pathophysiology, diagnosis, and treatment of pediatric anxiety disorders. We aim to guide clinicians in understanding the biology of anxiety disorders and to provide general guidelines for the proper diagnoses and treatment of these conditions early in life. Anxiety disorders are prevalent, associated with a number of negative life outcomes, and currently under-recognized and under-treated. the etiology involves both genes and environmental influences modifying the neural substrate in a complex interplay. Research on pathophysiology is still in its infancy, but some brain regions, such as the amygdala and the prefrontal cortex, have been implicated in fear and anxiety. Current practice is to establish diagnosis based purely on clinical features, derived from clinical interviews with the child, parents, and teachers. Treatment is effective using medication, cognitive behavioral therapy, or a combination of both. An introduction to the neuroscience behind anxiety disorders combined with an evidence-based approach may help clinicians to understand these disorders and treat them properly in childhood. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-01-01 2016-01-24T14:30:56Z 2016-01-24T14:30:56Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1516-4446-2013-S108 Revista Brasileira de Psiquiatria. São Paulo: Assoc Brasileira Psiquiatria, v. 35, p. S3-S21, 2013. 10.1590/1516-4446-2013-S108 S1516-44462013000500003.pdf 1516-4446 S1516-44462013000500003 http://repositorio.unifesp.br/handle/11600/35725 WOS:000325742100003 |
url |
http://dx.doi.org/10.1590/1516-4446-2013-S108 http://repositorio.unifesp.br/handle/11600/35725 |
identifier_str_mv |
Revista Brasileira de Psiquiatria. São Paulo: Assoc Brasileira Psiquiatria, v. 35, p. S3-S21, 2013. 10.1590/1516-4446-2013-S108 S1516-44462013000500003.pdf 1516-4446 S1516-44462013000500003 WOS:000325742100003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Revista Brasileira de Psiquiatria |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
S3-S21 application/pdf |
dc.publisher.none.fl_str_mv |
Assoc Brasileira Psiquiatria |
publisher.none.fl_str_mv |
Assoc Brasileira Psiquiatria |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da UNIFESP instname:Universidade Federal de São Paulo (UNIFESP) instacron:UNIFESP |
instname_str |
Universidade Federal de São Paulo (UNIFESP) |
instacron_str |
UNIFESP |
institution |
UNIFESP |
reponame_str |
Repositório Institucional da UNIFESP |
collection |
Repositório Institucional da UNIFESP |
repository.name.fl_str_mv |
Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP) |
repository.mail.fl_str_mv |
biblioteca.csp@unifesp.br |
_version_ |
1814268434754568192 |