Vitamin D and its relation to bone mineral density in postmenopause women

• Autor(a) principal: Labronici, Pedro José [UNIFESP]
• Data de Publicação: 2013
• Outros Autores: Blunck, Saulo Santos, Lana, Flavius Ribeiro, Esteves, Bruno Bandeira, Franco, José Sergio, Fukuyama, Junji Miller, Pires, Robinson Esteves Santos
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNIFESP
• Texto Completo: http://dx.doi.org/10.1016/j.rbo.2012.07.004; http://repositorio.unifesp.br/handle/11600/7790
• topic: Vitamin D; Osteoporosis; Bone density; Fractures, bone; Vitamina D; Osteoporose; Densidade óssea; Fraturas ósseas

OBJECTIVE:Compare the level of vitamin D with the bone mineral density (BMD) in postmenopausal women, with or without fractures.METHODS:250 women with mean age of 71.1 were evaluated. The serum levels of vitamin D considered sufficient were ≥ 30 ng/mL, insufficient between 20 and 30 ng/mL and deficient < 20 ng/mL. The bone mineral density was measured and considered osteopenia when T value total of lumbar spine or hip was between -1 and -2.5 and osteoporosis < 2.5. The patients with fractures accounted for 25.2%.RESULTS:There was no significant difference in the vitamin D (ng/mL) levels among the age groups (p = 0.25), the levels of fractures (p = 0.79) and the levels of BMD (p = 0.76).CONCLUSION:82% of the patients presented deficient and insufficient blood levels of vitamin D. Ours results showed any significant correlation between vitamin D levels and bone mineral density after adjusting for age.